1. e-Prints What are they?! How do they relate to CombeChem? Simon Coles CombeDay (08/01/2004)

2. Combichem Combechem The need for e-Prints DATAPUBLICATION DISSEMINATION

3. The need for e-Prints 100s of structures How do we disseminate? National Crystallography Service

4. Current e-Prints

6. Crystallographic e-Prints Set up data collection Collect data Process + correct images Solve structure Refine structure CIF RAW DATA DERIVED DATA RESULTS DATA 1 2 3 4 5 6

7. Crystallographic e-Prints EPrint (Local) EBank (World) JOURNAL PUBLICATION DATA HOLDING INVESTIGATION RAW DERIVED RESULTS CIF STRUCTURE REPORT DATASET (Contains DATAFILES) REPORT (EPrint) EBank REPORT

8. Crystallographic e-Prints

10. To conclude Recent advances through CombiChem, CombeChem & NCS activities have led to very high throughput crystallography These advances have shifted the experimental bottleneck from data acquisition to publication and dissemination e-Prints and e-Bank are the answer! They are also generic and therefore applicable to all aspects of CombeChem Thanks to Les Carr, Chris Bailey & Chris Gutteridge (IAM Group, ECS) and the UKOLN team (Bath University)