1. © 2013 Pearson Education, Inc. Chapter 13: Viruses, Viroids, and Prions $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Viral Characteristics Viral Cultivation Viral Infections Viruses and Cancer Prions/Viroids FINAL ROUND

2. © 2013 Pearson Education, Inc. Topic 1: Viral Characteristics $100 Question Viruses differ from bacteria in that viruses a. do not have any nucleic acid. b. are obligate intracellular parasites. c. are filterable. d. are not composed of cells. ANSWER BACK TO GAME

3. © 2013 Pearson Education, Inc. Topic 1: Viral Characteristics $100 Answer Viruses differ from bacteria in that viruses a. do not have any nucleic acid. b. are obligate intracellular parasites. c. are filterable. d. are not composed of cells. BACK TO GAME

4. © 2013 Pearson Education, Inc. Topic 1: Viral Characteristics $200 Question Which of the following statements about spikes is FALSE? a. They are used for absorption. b. They are used for nucleic acid replication. c. They are found only on enveloped viruses. d. They may cause hemagglutination. BACK TO GAME ANSWER

5. © 2013 Pearson Education, Inc. Topic 1: Viral Characteristics $200 Answer Which of the following statements about spikes is FALSE? a. They are used for absorption. b. They are used for nucleic acid replication. c. They are found only on enveloped viruses. d. They may cause hemagglutination. BACK TO GAME

6. © 2013 Pearson Education, Inc. Topic 1: Viral Characteristics $300 Question Viruses that infect bacteria are called a. bacteriophages. b. prions. c. viroids. d. complex viruses. BACK TO GAME ANSWER

7. © 2013 Pearson Education, Inc. Topic 1: Viral Characteristics $300 Answer Viruses that infect bacteria are called a. bacteriophages. b. prions. c. viroids. d. complex viruses. BACK TO GAME

8. © 2013 Pearson Education, Inc. Topic 1: Viral Characteristics $400 Question Viruses range in size from a. 10 to 100 nm in length. b. 10 to 1000 nm in length. c. 20 to 100 nm in length. d. 20 to 1000 nm in length. BACK TO GAME ANSWER

9. © 2013 Pearson Education, Inc. Topic 1: Viral Characteristics $400 Answer Viruses range in size from a. 10 to 100 nm in length. b. 10 to 1000 nm in length. c. 20 to 100 nm in length. d. 20 to 1000 nm in length. BACK TO GAME

10. © 2013 Pearson Education, Inc. Topic 1: Viral Characteristics $500 Question Which of the following is NOT used as a criterion to classify viruses? a. biochemical tests b. size c. morphology d. number of capsomeres BACK TO GAME ANSWER

11. © 2013 Pearson Education, Inc. Topic 1: Viral Characteristics $500 Answer Which of the following is NOT used as a criterion to classify viruses? a. biochemical tests b. size c. morphology d. number of capsomeres BACK TO GAME

12. © 2013 Pearson Education, Inc. What is the most common method used to identify viruses? a. serological methods b. observation of cytopathic effects c. PCR d. morphology Topic 2: Viral Cultivation $100 Question BACK TO GAME ANSWER

13. © 2013 Pearson Education, Inc. Topic 2: Viral Cultivation $100 Answer What is the most common method used to identify viruses? a. serological methods b. observation of cytopathic effects c. PCR d. morphology BACK TO GAME

14. © 2013 Pearson Education, Inc. Viruses CANNOT be cultured in a. laboratory animals. b. cell culture. c. embryonated eggs. d. culture media. Topic 2: Viral Cultivation $200 Question BACK TO GAME ANSWER

15. © 2013 Pearson Education, Inc. Viruses CANNOT be cultured in a. laboratory animals. b. cell culture. c. embryonated eggs. d. culture media. Topic 2: Viral Cultivation $200 Answer BACK TO GAME

16. © 2013 Pearson Education, Inc. What is cell deterioration due to viral infections termed? a. transformation b. transduction c. cytopathic effect d. plaques Topic 2: Viral Cultivation $300 Question BACK TO GAME ANSWER

17. © 2013 Pearson Education, Inc. What is cell deterioration due to viral infections termed? a. transformation b. transduction c. cytopathic effect d. plaques Topic 2: Viral Cultivation $300 Answer BACK TO GAME

18. © 2013 Pearson Education, Inc. Topic 2: Viral Cultivation $400 Question BACK TO GAME ANSWER Continuous cell lines are a. transduced cells. b. cancerous cells. c. developed from human embryos. d. derived from tissue slices.

19. © 2013 Pearson Education, Inc. Topic 2: Viral Cultivation $400 Answer BACK TO GAME Continuous cell lines are a. transduced cells. b. cancerous cells. c. developed from human embryos. d. derived from tissue slices.

20. © 2013 Pearson Education, Inc. Topic 2: Viral Cultivation $500 Question A plaque is theoretically formed by a. a single virus. b. viruses infecting primary cell lines. c. viruses injected into the yolk sac. d. viruses injected into the amniotic cavity. BACK TO GAME ANSWER

21. © 2013 Pearson Education, Inc. Topic 2: Viral Cultivation $500 Answer A plaque is theoretically formed by a. a single virus. b. viruses infecting primary cell lines. c. viruses injected into the yolk sac. d. viruses injected into the amniotic cavity. BACK TO GAME

22. © 2013 Pearson Education, Inc. Topic 3: Viral Infections $100 Question Which of the following is an example of a persistent viral infection in humans? a. cold sores b. cervical cancer c. shingles d. leukemia BACK TO GAME ANSWER

23. © 2013 Pearson Education, Inc. Topic 3: Viral Infections $100 Answer Which of the following is an example of a persistent viral infection in humans? a. cold sores b. cervical cancer c. shingles d. leukemia BACK TO GAME

24. © 2013 Pearson Education, Inc. Topic 3: Viral Infections $200 Question Which of the following is an example of a latent viral infection in humans? a. smallpox b. polio c. shingles d. mumps BACK TO GAME ANSWER

25. © 2013 Pearson Education, Inc. Topic 3: Viral Infections $200 Answer Which of the following is an example of a latent viral infection in humans? a. smallpox b. polio c. shingles d. mumps BACK TO GAME

26. © 2013 Pearson Education, Inc. How is a persistent viral infection different from a latent viral infection? a. It remains in equilibrium with the host. b. It can be reactivated by immunosuppression. c. The infectious virus appears suddenly. d. The infectious virus gradually builds up over a long period of time. Topic 3: Viral Infections $300 Question BACK TO GAME ANSWER

27. © 2013 Pearson Education, Inc. Topic 3: Viral Infections $300 Answer How is a persistent viral infection different from a latent viral infection? a. It remains in equilibrium with the host. b. It can be reactivated by immunosuppression. c. The infectious virus appears suddenly. d. The infectious virus gradually builds up over a long period of time. BACK TO GAME

28. © 2013 Pearson Education, Inc. Topic 3: Viral Infections $400 Question What is the primary effect of HTLV-1? a. decreased CD4 + T cells b. rapid mental deterioration c. increased white blood cell growth d. skin and mucous membrane lesions BACK TO GAME ANSWER

29. © 2013 Pearson Education, Inc. Topic 3: Viral Infections $400 Answer BACK TO GAME What is the primary effect of HTLV-1? a. decreased CD4 + T cells b. rapid mental deterioration c. increased white blood cell growth d. skin and mucous membrane lesions

30. © 2013 Pearson Education, Inc. Topic 3: Viral Infections $500 Question SSPE is a type of _____ infection and is caused by the _____ virus. a. latent; herpes simplex virus b. latent; echovirus c. persistent; measles d. persistent; rubella BACK TO GAME ANSWER

31. © 2013 Pearson Education, Inc. Topic 3: Viral Infections $500 Answer SSPE is a type of _____ infection and is caused by the _____ virus. a. latent; herpes simplex virus b. latent; echovirus c. persistent; measles d. persistent; rubella BACK TO GAME

32. © 2013 Pearson Education, Inc. Topic 4: Viruses and Cancer $100 Question Cancer-causing alterations to cellular DNA affect parts of the genome called a. introns. b. oncogenes. c. exons. d. sense strand. BACK TO GAME ANSWER

33. © 2013 Pearson Education, Inc. Topic 4: Viruses and Cancer $100 Answer Cancer-causing alterations to cellular DNA affect parts of the genome called a. introns. b. oncogenes. c. exons. d. sense strand. BACK TO GAME

34. © 2013 Pearson Education, Inc. Topic 4: Viruses and Cancer $200 Question Sarcoma is a cancer of _____ tissue. a. nervous b. epithelial c. muscular d. connective ANSWER BACK TO GAME

35. © 2013 Pearson Education, Inc. Topic 4: Viruses and Cancer $200 Answer Sarcoma is a cancer of _____ tissue. a. nervous b. epithelial c. muscular d. connective BACK TO GAME

36. © 2013 Pearson Education, Inc. Topic 4: Viruses and Cancer $300 Question Which of the following viruses have reverse transcriptase? a. Hepadnaviridae and Retroviridae b. bacteriophage families c. Herpesviridae and Retroviridae d. Retroviridae and Picornaviridae BACK TO GAME ANSWER

37. © 2013 Pearson Education, Inc. Topic 4: Viruses and Cancer $300 Answer Which of the following viruses have reverse transcriptase? a. Hepadnaviridae and Retroviridae b. bacteriophage families c. Herpesviridae and Retroviridae d. Retroviridae and Picornaviridae BACK TO GAME

38. © 2013 Pearson Education, Inc. Topic 4: Viruses and Cancer $400 Question a.T antigens appear in the nucleus of the cell. b.Cells lose their ability to divide. c.Cells tend to exhibit chromosomal abnormalities. d.Tumor-specific transplantation antigens appear on the cell. BACK TO GAME ANSWER Which of the following is NOT an effect of transformation?

39. © 2013 Pearson Education, Inc. Topic 4: Viruses and Cancer $400 Answer a.T antigens appear in the nucleus of the cell. b.Cells lose their ability to divide. c.Cells tend to exhibit chromosomal abnormalities. d.Tumor-specific transplantation antigens appear on the cell. BACK TO GAME Which of the following is NOT an effect of transformation?

40. © 2013 Pearson Education, Inc. Topic 4: Viruses and Cancer $500 Question After being transformed by viruses, what do many tumor cells contain on their cell surface? a. TSTA b. PrP c. PFU d. ICTV BACK TO GAME ANSWER

41. © 2013 Pearson Education, Inc. Topic 4: Viruses and Cancer $500 Answer After being transformed by viruses, what do many tumor cells contain on their cell surface? a. TSTA b. PrP c. PFU d. ICTV BACK TO GAME

42. © 2013 Pearson Education, Inc. Topic 5: Prions/Viroids $100 Question A viroid is a a. provirus. b. naked, infectious piece of RNA. c. capsid without a nucleic acid. d. complete, infectious virus particle. BACK TO GAME ANSWER

43. © 2013 Pearson Education, Inc. Topic 5: Prions/Viroids $100 Answer A viroid is a a. provirus. b. naked, infectious piece of RNA. c. capsid without a nucleic acid. d. complete, infectious virus particle. BACK TO GAME

44. © 2013 Pearson Education, Inc. Topic 5: Prions/Viroids $200 Question Viroids infect a. animals. b. insects. c. plants. d. bacteria. BACK TO GAME ANSWER

45. © 2013 Pearson Education, Inc. Topic 5: Prions/Viroids $200 Answer Viroids infect a. animals. b. insects. c. plants. d. bacteria. BACK TO GAME

46. © 2013 Pearson Education, Inc. Topic 5: Prions/Viroids $300 Question Scrapie is an example of an infection caused by a a. prion. b. viroid. c. difficult-to-detect virus. d. difficult-to-grow bacterium. BACK TO GAME ANSWER

47. © 2013 Pearson Education, Inc. Topic 5: Prions/Viroids $300 Answer BACK TO GAME Scrapie is an example of an infection caused by a a. prion. b. viroid. c. difficult-to-detect virus. d. difficult-to-grow bacterium.

48. © 2013 Pearson Education, Inc. Topic 5: Prions/Viroids $400 Question One human disease caused by a prion is a. mad cow disease. b. Creutzfeldt-Jakob disease. c. scrapie. d. tularemia. BACK TO GAME ANSWER

49. © 2013 Pearson Education, Inc. Topic 5: Prions/Viroids $400 Answer One human disease caused by a prion is a. mad cow disease. b. Creutzfeldt-Jakob disease. c. scrapie. d. tularemia. BACK TO GAME

50. © 2013 Pearson Education, Inc. Topic 5: Prions/Viroids $500 Question It is hypothesized that viroids evolved from a. viruses. b. exons. c. introns. d. prions. BACK TO GAME ANSWER

51. © 2013 Pearson Education, Inc. Topic 5: Prions/Viroids $500 Answer It is hypothesized that viroids evolved from a. viruses. b. exons. c. introns. d. prions. BACK TO GAME

52. © 2013 Pearson Education, Inc. FINAL ROUND Question Which type of viral nucleic acid functions as mRNA? a. RNA, double-stranded b. RNA, – strand c. RNA, + strand d. RNA, reverse transcriptase BACK TO GAME ANSWER

53. © 2013 Pearson Education, Inc. FINAL ROUND Answer Which type of viral nucleic acid functions as mRNA? a. RNA, double-stranded b. RNA, – strand c. RNA, + strand d. RNA, reverse transcriptase BACK TO GAME