1. Antibiotics Versus Conservative Surgery for Treating Diabetic Foot Osteomyelitis: A Randomized Comparative Trial Featured Article: José Luis Lázaro-Martínez, Javier Aragón- Sánchez, and Esther García-Morales Diabetes Care Volume 37: 789-795 March, 2014

2. STUDY OBJECTIVE To compare the treatment outcomes of diabetic foot osteomyelitis in patients treated exclusively with antibiotics versus patients who underwent conservative surgery Follow-up occurred for 12 weeks after healing Lázaro-Martínez J. L. et al. Diabetes Care 2014;37:789-795

3. STUDY DESIGN AND METHODS Prospective randomized comparative trial was carried out in diabetes patients with neuropathic foot ulcers complicated by osteomyelitis Patients were randomized into two groups: Antibiotics group (AG) Surgical group (SG) Antibiotics were given for 90 days in AG SG received conservative surgery with postoperative antibiotic treatment for 10 days Lázaro-Martínez J. L. et al. Diabetes Care 2014;37:789-795

4. RESULTS 18 patients (75%) achieved primary healing in AG and 19 (86.3%) in SG Median time to healing was 7 weeks in AG and 6 weeks in SG Conditions of four patients from AG worsened (16.6%), and they underwent surgery Three patients from SG required reoperation No difference was found between the two groups regarding minor amputations Lázaro-Martínez J. L. et al. Diabetes Care 2014;37:789-795

8. CONCLUSIONS Antibiotic therapy and surgical treatment had similar outcomes in terms of healing rates, time to healing, and short-term complications Lázaro-Martínez J. L. et al. Diabetes Care 2014;37:789-795