1. Lymph System
Types of Immunity

2. Immune Cells Macrophages T cells B cells Helper T Memory T Killer T
Suppressor T
B cells
Plasma
Memory B

3. 1- Innate immunity: ~basic resistance to disease that a species
Types of Immunity
1- Innate immunity: ~basic resistance to disease that a species
is born with 3

4. 4 types of innate immunity
1. 1st line of defense
Skin, mucous, oil, sweat, tears and saliva
2. Inflammation response
Damaged cells and WBC release histamine dilating blood vessels allowing fluid to enter area
3. Genetic Immunity Pathogens can affect certain host species but not others
4. Cell mediated
destruction of foreign particles by T-cells and Macrophages 4

5. Steps to: CELL MEDIATED IMMUNITY
1- foreign invader is engulfed by MACROPHAGE
2- macrophage presents antigen on surface to
HELPER T-CELL
3- HELPER T-CELL is activated and calls in
KILLER T-CELLS, SUPPRESSOR T-CELLS,
MEMORY T-CELLS
4- KILLER T-cells go into circulation and hunt
down bad guys—destroy by LYSIS of cell membrane
5- SUPPRESSOR T-CELLS stop response once antigen is destroyed

6. http://cell mediated immune animation6

7. ~gradually building up resistance using
2- Acquired immunity:
~gradually building up resistance using
antibodies
~defends against SPECIFIC individual
pathogens

8. 2 types of Acquired immunity
1. Passive – antibodies from another source
mom to unborn baby
placenta and through milk
2. Active-individual produces own antibodies
a. Vaccines: injections of weakened, dead or incomplete pathogens
b. Antibody Mediated: exposed to antigen, your body will produce
antibodies
Passive- artificial – ex. Snake bites, rabies, antiserum 8

9. ANTIBODY MEDIATED 1- Antigen is engulfed by a MACROPHAGE
2- macrophage/antigen stimulates HELPER T-CELL
3- HELPER T-cell will make SUPPRESSOR T activates B-cells in
lymph tissue
4- Activated B-cell makes memory B-cells and plasma cells
5- Plasma cell secretes ANTIBODIES
6- Antibodies bind to pathogen and mark for macrophages to
engulf OR antibodies destroy pathogen themselves
7- Once pathogen is destroyed, Suppressor T-cells stop immune
response 9

10. antibody mediated immune animation10