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Topics in Human Pathophysiology Fall 2009 Instructor: Theresa Martin (CSM) Gilead Drug Safety and Public Health.

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Presentation on theme: "Topics in Human Pathophysiology Fall 2009 Instructor: Theresa Martin (CSM) Gilead Drug Safety and Public Health."— Presentation transcript:

1 Topics in Human Pathophysiology Fall 2009 Instructor: Theresa Martin (CSM) Gilead Drug Safety and Public Health

2 Course website

3 Levels of Body Organization Atoms Molecules Cells Tissues Organs Organ Systems Organism

4 Figure 1.1

5 Figure 3.1

6 Cell Structure and Function Cells are the basic unit of life Cells are composed of chemicals Human cells have a membrane, cytoplasm, and nucleus

7 Figure 3.14

8 Water a polar molecule

9 Properties of Water A great solvent A great reactant Good at holding temperature High heat of vaporization

10 Figure 2.9

11 Figure 3.14

12 The Cell Membrane Composed of phospholipid bilayer with embedded proteins that serve a variety of functions Semipermeable Allows passive transport and also has active transport (pumps) Has important communication functions

13 13 Figure 02.04 The Cell (Plasma) Membrane

14 Diffusion

15 Figure 3.8

16 Figure 3.9a

17 Figure 3.10 Bulk Transport

18 Figure 21.2a

19 Figure 3.11 19

20 Cytoplasm Contains cytosol and organelles Organelles have specific functions Enzymes catalyze most reactions

21 Figure 3.14

22 Figure 2.23 Proteins in the cells have a variety of functions including structural proteins, and enzymes. Enzymes catalyze almost all cellular reactions “metabolism” Enzymes

23 Figure 3.14

24 Cell Nucleus Contains genetic material - DNA DNA has genes on it. DNA is a double strand with two chains of nucleotides linked up anti-parallel

25 25


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