1. ©2007 NIRT: Evaluating Oversight Mechanisms for Active Nanostructures and Nanosystems: Learning from Past Technologies in a Societal Context Grant No. 0608791 Susan M. Wolf, JD 1 ; Efrosini Kokkoli, PhD 2 ; Jennifer Kuzma, PhD 3 ; Jordan Paradise, JD 1 ; Gurumurthy Ramachandran, PhD 4 1. Law School and Consortium on Law and Values in Health, Environment & the Life Sciences; 2. Department of Chemical Engineering and Materials Science; 1. Law School and Consortium on Law and Values in Health, Environment & the Life Sciences; 2. Department of Chemical Engineering and Materials Science; 3. Hubert H. Humphrey Institute of Public Affairs; 4. School of Public Health, University of Minnesota, Minneapolis, MN, 55455 3. Hubert H. Humphrey Institute of Public Affairs; 4. School of Public Health, University of Minnesota, Minneapolis, MN, 55455 Project Goals (Phases I-III) Assessment of oversight approaches in 6 historical case studies utilizing expert elicitation, multi-criteria assessment of oversight models, literature review, and consensus processes. Case studies are: >drugs >medical devices >chemicals in the environment >chemicals in the workplace >gene transfer research (“gene therapy”) >genetically engineered organisms in the food supply Application of oversight lessons to nanobio Development of oversight models for nanobio products and research Anticipated Products: Publication of individual papers analyzing the 6 historical case studies Collaborative publication of comparative analysis across the 6 studies Publication of group-authored consensus paper on lessons for nanobiotechnology oversight Wide dissemination of policy analysis and normative oversight recommendations through hard copy, web-based resources, and targeted efforts to reach key stakeholders Creation of workshop series for law and public policy students Public conference to present consensus report and papers authored by Investigators and Working Group members and to seek public input Presentation of work by Investigators at outside conferences Project-Related Publications and Works in Progress: J. Kuzma. Nanotechnology Oversight: Just do it. Environmental Law Reporter. 2006;12:10913-23. M. Kandlikar, G. Ramachandran, A.D. Maynard, B. Murdock, W.A. Toscano. Health Risk Assessment for Nanoparticles: A case for using expert judgment. Journal of Nanoparticle Research. 2007;9:137-56. J. Paradise, S.M. Wolf, E. Kokkoli, G. Ramachandran, R. Hall, J. Kuzma. Developing Oversight Frameworks for Nanobiotechnology. Minnesota Journal of Law, Science & Technology. 2007;9: __ (forthcoming). J. Kuzma, J. Paradise, G. Ramachandran, J. Kim, A. Kokotovich, S.M. Wolf. An Integrated Approach to Oversight Assessment for Emerging Technologies. (submitted to Risk Analysis, September 2007). J. Kuzma, A. Kokotovitch. Upstream Oversight Assessment for Agrifood Nanotechnology: A Case Studies Approach. (submitted to Risk Analysis, May 2007). Phase I (Current Phase): Developing Criteria for Assessment of Historical Oversight Models