1. European Research in Nanosciences and Nanotechnologies and Perspectives for International Co-operation Disclaimer: Note that this presentation is not legally binding and does not represent any commitment on behalf of the European Commission http://cordis.europa.eu/nanotechnology/ nicholas.deliyanakis@ec.europa.eu Nicholas Deliyanakis European Commission DG Research - G4 : Nano S&T and Converging Science and Technologies

2. Nanotechnology Medicine and Health Information Technology Materials Science Food, Water and the Environment InstrumentsEnergy Production / Storage GMR Hard Disk Hydrogen Fuel Cells Lightweight and strong Drug delivery Tunneling microscopy Remediation methods Potential to serve society by addressing important problems to support industrial competitiveness

3.  More knowledge  Research  Infrastructures  Education  Capacity of application  Innovation  Patents  Regulation Issues to be addressed: Funding and Policy  Reliability  Metrology  Standards  Risk assessment  Societal acceptance  Balance and perception of risks and benefits  Conformity to ethical principles  Expected response to society needs, to people’s expectations and concerns some issues are better addressed at local, national, EU or global level

4. Nanosciences and Nanotechnologies: An Action Plan for Europe 2005-2009 http://cordis.europa.eu/nanotechnology/actionplan.htm Actions to be implemented by Commission and Member States for integrated, safe and responsible policy: 1.Research & Development 2.Infrastructures 3.Human Resources 4.Industrial Innovation 5.Integrating the Societal Dimension 6.Public Health, Safety, Environmental and Consumer Protection 7.International Co-operation 8.Co-ordination of activities

5. Background: Nanotechnology R&D in FP6 More than 1.3 billion Euro in more than 550 projects EC funding by FP6 programme, M€

6. Nanotechnology R&D in the World 2004 ~8 Billion $ 2005 ~10.5 Billion $ Global figures for 2005 M$ (1€ ~ 1.25$) Source: EC, Lux Research

7. NMP FP6 projects, e.g. Examples of FP6 projects CANAPE: Carbon Nanotubes for Applications in Electronics, Catalysis, Composites and Nano-Biology – University of Cambridge (UK) NAIMO: Nanoscale Integrated processing of self-organizing Multifunctional Organic Materials - Université Libre de Bruxelles (BE) NANOFUN-POLY: Nanostructured and functional polymer-based materials and nanocomposites - Consorzio Interuniversitario Scienza e Tecnologia dei Materiali (IT) RADSAS: Rational Design and Characterisation of Supramolecular Architectures on Surfaces - Eidgenössische Materialprüfungs- und Forschungsanstalt (CH) BIOMACH: Molecular Machines - Design and Nano-Scale Handling of Biological Antetypes and Artificial Mimics - Forschungszentrum Karlsruhe GmbH (DE) Cornea engineering: Three-dimensional reconstruction of human corneas by tissue engineering” - Centre National de la Recherche Scientifique / Rhône Alpes (FR) Ambio: Advanced nanostructured surfaces for the control of biofouling - University of Birmingham (UK) ANVOC: Application of nanotechnologies for separation and recovery of volatile organic compounds from waste air streams – S&T Research Council of Turkey (TR) NANOSAFE2: Safe production and use of nanomaterials - Commissariat à l'Energie Atomique (FR) Nanologue: Facilitating dialogue between research, business and the civil society to improve the quality of life, create wealth and reduce impacts to society - Wuppertal Institute for Climate, Energy and the Environment (DE)

8. Examples of FP6 projects addressing impact NANOTOX IMPARTwww.impart-nanotox.org NANOSAFE2www.nanosafe.org PARTICLE RISKwww.iom-world.com/particlerisk POLYSOApolysoa.web.psi.ch ANTISTORMantistorm.isac.cnr.it DIPNA CELLNANOTOX NANOSH SAPHIR NANOINTERACT Total Funding for EHS in FP6 ~25 M€

9. CO-OPERATION 32413 -Health6100 -Food, Agriculture and Biotechnology1935 -Information and Communication Technologies9050 -Nanosciences, Nanotechnologies, Materials and new Production Technologies3475 -Energy2350 -Environment (including Climate Change)1890 -Transport (including Aeronautics)4160 -Socio-economic Sciences and Humanities 623 -Space1430 -Security1400 IDEAS (European Research Council) 7510 PEOPLE 4750 CAPACITIES 4097 JRC 1751 FP7 (EC) Budget, M€ 50521 M€

10. 7 th FRAMEWORK PROGRAMME 2007-2013 New features of FP7 include:  Longer duration (7 years)  Large increase in annual budget (from ~4,500 to ~7,000M€)  Integration of International Co-operation into all four programmes  Simplification of operation  Focus on developing research that meets the needs of European industry, through the work of Technology Platforms and the new Joint Technology Initiatives  Establishment of a European Research Council, funding European research on the sole basis of excellence

11. NMP-2007-1.1-1 CP Nano-scale mechanisms of bio/non-bio interactions NMP-2007-1.1-2 CP Self-assembling and self-organisation NMP-2007-1.1-3 CSA Support to ICPC researchers in nanotechnology and creation of a free and open electronic archive of nanosciences and nanotechnologies scientific and technical publications NMP-2007-1.1-4 CSA Development of methodology, collection and elaboration of scientific-technical and socio-economic data and studies on nanosciences and nanotechnologies, including risk assessment, and establishment of an observatory NMP-2007-1.1-5 CSA (ERANET) ERANET Plus in nanosciences Funding for Nanotechnology R&D in FP7 More than 50 activities in the calls opened in 2007 are directly relevant Many more activities are indirectly relevant (e.g. in Health) 300-400M€ estimated in 2007 Doubling of the FP6 funding expected over duration of FP7 Nanoscience

12. NMP-2007-1.2-1 Large CP Pilot lines to study, develop and up-scale nanotechnology- based processes from laboratory NMP-2007-1.2-2 SME-targeted CP Equipment and methods for nanotechnology NMP-2007-1.2-4 CSA Coordination in nanometrology NMP-2007-1.2-5 CSA Examining capacity building in nanobiotechnology NMP-2007-3.4-1 SME-targeted CP Rapid Manufacturing Concepts for Small Series Industrial Production NMP-2007-3.5-1 Large CP Processes and Equipment for High Quality Industrial Production of 3-Dimensional Nanosurfaces NMP-2007-3.5-2 Large CP Production Technologies and equipment for Micro- Manufacturing NMP-2007-4.0-2 SME-targeted CP Application of new materials including bio-based fibres in high-added value textile products Technology development

13. NMP-2007-1.3-1 Large CP Specific, easy-to-use portable devices for measurement and analysis NMP-2007-1.3-2 CP Risk assessment of engineered nanoparticles on health and the environment NMP-2007-1.3-3 CSA Scientific review on the data and studies on the potential impact on health, safety and the environment of engineered nanoparticles NMP-2007-1.3-4 CSA Creation of a critical and commented database on the health, safety and environmental impact of nanoparticles NMP-2007-1.3-5 CSA Coordination in studying the environmental, safety and health impact of engineered nanoparticles and nanotechnology based materials and products HEALTH-2007- 1.3-4 CP Alternative testing strategies for the assessment of the toxicological profile of nanoparticles used in medical diagnostics SiS-2007-1.2.3.2- CT CSA Science in Society: Nanoscience and Nanotechnology Impact assessment and societal issues

14. NMP-2007-2.1.1 Large CP Nanostructured polymer-matrix composites NMP-2007-2.1.2 CP Nanostructured coatings and thin films NMP-2007-2.1.3 CSA Characterisation of nanostructured materials NMP-2007-2.2-1 Large CP Organic materials for electronics and photonics NMP-2007-2.2-2 CP Nanostructured materials with tailored magnetic properties NMP-2007-2.2.-3 CP Advanced material architectures for energy conversion NMP-2007-2.4-2 CP Nanostructured catalysts with tailor-made functional surfaces NMP-2007-2.4-3 CP Renewable materials for functional packaging applications NMP-2007-2.5-2 CP Modelling of microstructural evolution under work conditions and in materials processing Nanomaterials

15. ENERGY-2007.1.2.4 CP Novel nanostructured materials for hydrogen storage ENERGY-2007.1.1.1 CP Basic research for materials and processes for Polymer Electrolyte Membrane Fuel Cells (PEMFC) ENERGY-2007.1.1.2 CP Basic research on materials and processes for High Temperature Fuel Cells (SOFC & MCFC) ENERGY-2007.1.2.1 CP New materials and processes for advanced electrolysers ENERGY-2007.1.2.2 CP New materials and processes for advanced multi-fuel processors AAT-2007.1.1.2 CP, CSA Aerostructures Nanomaterials –cont’d ICT-2007.3.1 CP, NoE, CSA Next generation nanoelectronics components and electronics integration ICT-2007.8.1 CP, CSA (CA only) Nano-scale ICT devices and systems Nanoelectronics

16. NMP-2007-4.0-4 Large CP Substantial innovation in the European medical industry: development of nanotechnology-based systems for in- vivo diagnosis and therapy (in coordination with topics HEALTH-2007-2.4.1-7 and HEALTH-2007-1.2-3) HEALTH-2007-2.4.1- 7 CP Improving targeted drug delivery to cancer cells for cancer therapeutics other than gene therapy HEALTH-2007-1.2.3 Large CP Novel targeted imaging probes for early in vivo diagnosis and/or evaluation of response to therapy NMP-2007-2.3.-1 Large CP Highly porous bioactive scaffolds controlling angiogenesis for tissue engineering NMP-2007-1.2-3 CSA Analysis of the ethical, regulatory, social and economic environment of nanomedicine ICT-2007-5.1 Large CP, CSA Personal Health Systems for Monitoring and Point-of-Care diagnostics HEALTH-2007-1.4.4 Large CP 2 nd call Development of emerging gene therapy tools and technologies for clinical application Nanomedicine NB: Many more activities in the Health theme are relevant to nanomedicine,Health theme e.g. imaging, stem cells and translating research for human health

17. ICT-2007.3.6 CP, NoE, CSA 2 nd call Micro/nanosystems ICT-2007.3.5 CP, NoE, CSA 2 nd call Photonic components and subsystems ICT-2007-C CP, CSA (CA only) FET (Future and Emerging Technologies) Open (Open call for bottom-up activities) AAT-2007.6.1.4 CP, CSA Life-cycle [of air vehicles, including increased use of nanotechnologies] KBBE-2007-2-3-04 CP Nano-devices for quality assurance, food safety and product properties KBBE-2007-2-4-04 CP Innovative and safe packaging KBBE-2007-2-5-02 CP Converging technologies and their potential for the food area Other Important Topics Please consider also opportunities within COSTCOST actions (funding for co-ordination activities) http://www.cost.esf.org/

18. Ideas – European Research Council Human Resources Infrastructures & SMEs PEOPLE-2007-1-1- ITN Marie Curie Initial Training Networks (all research areas) PEOPLE-2007-5-2- Awards Marie Curie Awards (all research areas) ERC-2007-StGERC Starting Independent Researcher Grants (all research areas) Expected in 2 nd call ERC Advanced Investigator Grants (all research areas) Please consider also the opportunities in educational programmes managed by DG EACeducational programmes http://ec.europa.eu/education/programmes/programmes_en.html INFRA-2007- 2.2.1.27 Combination CP/CSA PRINS, Pan-European Research Infrastructures for Nano- structures (from 2006 ESFRI Roadmap) FP7-SME-2007-1Research for the benefit of SMEs

19. a) Optimising the use and development of the best research infrastructures existing in Europe Co-ordinated calls dedicated to nanotechnology are envisaged b) Pooling of resources (national, private, European) to support the emergence of new facilities required by the scientific community within the next 10-20 years -European Strategy Forum on Research Infrastructures (ESFRI): http://www.cordis.europa.eu/esfri/ -Integration through Networks of Excellence Infrastructures actions

20. a)Workshop on research training in N&N, 14-15 April 2005 cordis.europa.eu/nanotechnology/src/educationworkshop.htm b)Educational programmes (Erasmus Mundus, Socrates- Erasmus) e.g. Erasmus Mundus Masters course in N&N c)Nanotechnology Award (ongoing discussions with Science and Society directorate) d)Joint initiatives with Marie Curie actions in FP7 are envisaged Human Resources actions

21. a)Better co-operation between industry and R&D organisations, encouragement of entrepreneurship  NanoForum, a European N&N gateway www.nanoforum.org  NanoRoadSME, NanoRoadmap projects  Exploitation Strategy Seminars  Risk-Sharing Finance Facility (RSFF)  Competitiveness and Innovation Programme (CIP) b)Increased involvement of industry in EU R&D projects, in particular of SMEs  3 Integrated Projects dedicated to SMEs Industrial Innovation actions

22. c)Digital N&N library  Implementation by a support or coordination action in FP7 d) Pre-normative R&D and metrology for nanotechnology  Two projects in NMP, Nano-Strand and Nanotransport; also addressed in IST e) Patent systems  Cooperation with EPO Working Group on Nanotechnology e.g. patent regime, patent analysis, expert exchange, patent monitoring Industrial Innovation actions

23. Industrial Innovation Patents: In 500 FP5 projects (Growth Programme), an average of 0.9 patents per projects were applied for and 0.4 were granted. In FP6 so far (sample of 35 projects), about 3 patents per project have been (or will be) filed ~45% from IPs ~55% from STREPs Most patents in: Nanobiotechnology, esp. nanomedicine, self-assembly, nanotubes, organic electronics, sensors and instruments

24. ADDRESSING EXPECTATIONS AND CONCERNS: ADDRESSING EXPECTATIONS AND CONCERNS: A real partnership between science, society and policy is a key element of governance: Open dialogue with open results. a)Ethical reviews of projects carried out, where needed b)European Group of Ethics is assessing Nanomedicine (opinion in autumn 2006) Societal Dimension actions

25. c)Studies and foresight activities  NanoRoadSME projectwww.nanoroad.net  NanoRoadMap projectwww.nanoroadmap.it d)Social dialogue undertaken through funded projects and events  Nanologue projectwww.nanologue.net  Nanodialogue projectwww.nanodialogue.org  “Communicating Science, A survival kit for Scientists” ec.europa.eu/research/science-society/ pdf/communicating-science_en.pdf e)Publicity material in many languages http://cordis.europa.eu/nanotechnology/src/pressroom.ht m Societal Dimension actions

26. a) Declaration or “code of good conduct” – dedicated international dialogue (global meetings in Alexandria (US), 2004, Tokyo, 2006, and Brussels, 2007) b) Issues of mutual benefit - (i) a new ISO group is operational, (ii) OECD is becoming increasingly active and (iii) a co-ordinated EU/USA call for proposals in (eco)toxicology is being negotiated c) Database of publications: Addressed in the first FP7 call for proposals International Cooperation actions

27. General principles on international co-operation l The Commission seeks international debate on nanotechnology-related issues such as public health, safety, environment, consumer protection, risk assessment, metrology, norms, …; l The EU R&D programmes are open to the World; Europe even funds research teams in Third Countries; l Europe promotes the monitoring and sharing at international level of information related to the scientific, technological, economical & social development of nanotechnology; l Europe strives for an international “code of conduct” for the responsible development of nanotechnology, and to avoid a “nano-divide”.

28. Main International Fora and Initiatives on Nanotechnology ISO, IEEE, Int. Comm. Weights & Measures standardisation, metrology IRGC, ICON about risks industry-led OECD CSTP proposed WP on nanotechnology OECD NESTI nanotechnology indicators UNESCO ethics incl. risk assessment G8 Carnegie Group coordination by ICGB OECD JM CHEMICALS WP safety nanomaterials characterisation, metrology, toxicity, … OECD Global Science Forum World Social Forum Global (informal) governmental dialogue on responsible nanotechnology incl. governance & societal dialogue Observatory? World Economic Forum APEC, ANF, NEPAD macro-regions INC industry-led Meridian Inst., UNIDO, NEPAD against « divide »

29. a) Creation of a Commission Interservice Group to monitor and oversee the implementation of the Action Plan, see cordis.europa.eu/nanotechnology/src/contacts.htm  It is important to have a regular interaction with Member States (currently: Council Research working party; a “nano” group for international cooperation; and groups for regulation) b) Reporting: We plan to issue a report at the end of 2007 and one at the end of 2009 c) Activities to foster beneficial applications: addressed in proposals for FP7 calls for proposals Co-ordination actions

30. Inter-institutional activity The Commission’s approach has received strong support from  Council of Ministers (European Strategy on Nanotechnology)  European Economic and Social Committee –Opinion CESE 582/2006  European Parliament –Resolution (2006)392, Sep 06

31. References http://cordis.europa.eu/nanotechnology/src/eu_funding.htm FP7: FP7: http://cordis.europa.eu/fp7/home_en.htmlhttp://cordis.europa.eu/fp7/home_en.html FP7 calls: FP7 calls: http://cordis.europa.eu/fp7/dc/index.cfm http://cordis.europa.eu/fp7/dc/index.cfm Nanotechnology homepage: http://cordis.europa.eu/nanotechnology/ Nanosciences and Nanotechnologies: An Action Plan for Europe 2005-2009 http://cordis.europa.eu/nanotechnology/actionplan.htm Additional information on nanotechnology: