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Introduction to NMR Spectroscopy and Imaging Review (Spring Term, 2011) Department of Chemistry National Sun Yat-sen University 核磁共振光譜與影像導論.

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Presentation on theme: "Introduction to NMR Spectroscopy and Imaging Review (Spring Term, 2011) Department of Chemistry National Sun Yat-sen University 核磁共振光譜與影像導論."— Presentation transcript:

1 Introduction to NMR Spectroscopy and Imaging Review (Spring Term, 2011) Department of Chemistry National Sun Yat-sen University 核磁共振光譜與影像導論

2 Basics of NMR and NMRI Magnetic field Magnetic moment, spin, quadrupolar nucleus Rotation, precession, nutation Pulse

3 1D NMR Spectroscopy Chemical shift (shielding, down/up field, effects of bonding, isotope, temp, pH…) J coupling (bonding, Karplus equation, strong coupling) T1, T2 measurement Polarization transfer, DEPT

4 2D NMR Basics COSY (TOCSY) NOESY HSQC HMBC

5 Solid State NMR Basics Magic Angle Spinning Cross Polarization Multi-quantum MAS Decoupling and Recoupling Applications to materials (inorganic compound, polymer, liquid crystal, nanomaterial) and biomedicine

6 Basic NMR Imaging General aspects of imaging Gradient fields Phase and frequency encoding Weighted images (T1, T2, Chemical shift, diffusion, diffusion tensor, temp, pH, biochemical events/processes …)


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