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Cortical vs. subcortical loops. Lateral inhibition in striatum.

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Presentation on theme: "Cortical vs. subcortical loops. Lateral inhibition in striatum."— Presentation transcript:

1 Cortical vs. subcortical loops

2 Lateral inhibition in striatum

3 Switching from one action to another

4 Direct and indirect pathways

5 Hyperdirect pathway

6 Lesions that cause hemiballism

7 Direct pathway

8 Indirect pathways

9 Loops through the basal ganglia Circuit nameBasal ganglia regions: Connected with:Functions to control: SkeletomotorPutamen; GPi, and SNpr VL/VA; motor cortex, prefrontal cortex Actions OculomotorBody of the caudate, SNpr Intralaminar nuclei, MD, VA; frontal and parietal eye fields; superior colliculus Gaze and orienting movements Dorsolateral prefrontal Head of the caudate, GPi and SNpr VA, VL and MD;Executive function, strategic planning OrbitofrontalCaudate, SNpr, ventral pallidum MD; orbitofrontal cortexMotivation, ability to play well with others Anterior cingulate aka limbic Ventral striatum, ventral pallidum MD; anterior cingulumEmotionality, motivated behavior


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