2. DNA STANDS FOR DEOXYRIBONUCLEIC ACID. THIS IS JUST A CHEMICAL WHICH IS PART OF THE HUMAN BODY. OFF THIS STRAND OF DNA, YOU WILL SEE A BASE. THIS IS WHERE ALL OF THE CHEMICALS SUCH AS ADDONINE AND GUYNINE WILL BE FOUND. HERE IS A BASE WHERE THE CHEMICALS WILL COME OFF.

3. Genes are what make you up as a person. A hereditary unit consisting of a sequence of DNA that occupies a specific location on a chromosome and determines a particular characteristic in an organism. Genes undergo mutation when their DNA sequence changes

4. Genes are passed on through chromosomes These come from the parents The parents chromosomes which they pass onto there child come from there parents and so on.

5. The genomics: GTL program is DOE next step in genomics building on data and resources from the Human Genome Project, the Microbial Genome Program, and systems biology to accelerate understanding of dynamic living systems for energy and environmental applications. The Human Project ends in 2003 with the completion of the human genetic sequence. A working draft of the entire human genome sequence was announced in June 2000, with analyses published in February 2001. An important feature of this project is the federal government long- standing dedication.

6. Osteogenesis Imperfecta (OI) Osteogenesis Imperfecta is a genetic condition which affects the development of collagen, a protein in the bone, skin and other tissues. In OI, defective collagen means that the bones are extremely fragile and can fracture as a result of everyday movements. Simple movements such as opening a door or turning over in one’s sleep can cause these fractures.

7. How Is OI Passed On? The pattern of inheritance in many in many families with OI is autosomal dominant. Each and every child of an affected parent has a 50% chance of inheriting the faulty gene and of having OI. However, there are several hundred different mutations which can give rise to OI and many people with OI have no family history of the condition. This can be a result of spontaneous genetic mutation or been inherited in a different way.

8. How People Can Be Affected In children with severe OI, a specially adapted wheelchair may be their only chance of mobility as they are unlikely to stand or walk. People with OI may have blue whites to their eyes, discoloured or fragile teeth, loose joints, bruising and nose bleeds. They may also have problems with their hearing, with their spine and respiratory problems. The peak time for fractures is the first 15 years of life.

9. Credits By Arjun Kumar Thomas Spurway Tony Mabbutt Stefan Bertin Dilir Habibi