1. Synapse and Catapult– New NIH OTT Technology Transfer Tools Ajoy K. Prabhu, M.S., M.B.A. Group Leader, Marketing Office of Technology Transfer National Institutes of Health U.S. Department of Health & Human Services Federal Lab Consortium Mid-Atlantic Regional Meeting October 22, 2007

2. NIH Office of Technology Transfer Tech. Transfer Service Center Cancer Infectious Diseases & Medical Devices General Medicine Marketing Group NIH OTT Technologies Available for Licensing Brand Awareness & Networking New Inventions

3. NIH Office of Technology Transfer New Inventions Tech. Transfer Service Center Brand Awareness & Networking NIH OTT Technologies Available for Licensing Marketing Group Cancer Infectious Diseases & Medical Devices General Medicine

4. NIH Office of Technology Transfer NIH OTT Technologies Available for Licensing Companies Synapse

5. NIH Office of Technology Transfer Synapse SM 5

6. NIH Office of Technology Transfer Synapse SM has made it possible for OTT to reach a wider business market by matching its portfolio to the research interests of biotechnology and pharmaceutical companies. OTT is able to proactively market and provide individualized and targeted information to companies that were unaware of the scientific possibilities available to them at NIH and FDA. Synapse SM can also be used to address other research and development challenges, including patent prosecution and enforcement, searching for experts, and portfolio management. Synapse SM Benefits 6

7. NIH Office of Technology Transfer Synapse SM draws from several databases:  TechTracS ®, the internal database containing NIH and FDA intramural research portfolios  U.S. Patent and Trademark Office (USPTO) patent applications and issued patents  CRISP (Computer Retrieval of Information on Scientific Projects), the database of millions of records of HHS/NIH funded biomedical research projects conducted at universities, hospitals, and other research institutions.  RaDiUS ® (Research and Development in the United States), a database maintained by the RAND Corp. that includes all research grants and contracts awarded by federal agencies  Medline ®, a database containing abstracts or full text of 16 million articles published in nearly 5000 journals  Millions of records of biomedical news stories. Data Sources The data are transformed and stored to allow for seamless—and rapid—cross-linking between databases. 7

8. NIH Office of Technology Transfer Analyze ~7,000 NIH IP for licensing Help find licensing partners Search IP for VCs and Angel Investors Search USPTO for NIH-complimentary IP Extramural grantees  intramural IP Synapse SM – Current Uses 8

9. NIH Office of Technology Transfer Synapse Dem Synapse Demonstration Synapse Demonstration

10. For further information http://www.ott.nih.gov Science. Ideas. Breakthroughs.