1. Astrobiology: The Nature of Life (Chapter 3) Properties of Living Systems Evolution as a Unifying Theme Structural Features of Living Systems Biochemical and Molecular Features of Living Systems Instructional Features of Living Systems Evolution as a Unifying Theme Extremophiles on Earth and Elsewhere Define Life (homework assignment and rappateur session)

2. Properties of Living Systems Not laws From Bennett et al.: –Order (hierarchy) –Reproduction –Growth and development –Energy use –Response to the environment (open systems) –Evolution and adaptation

3. Properties of Living Systems From Taylor: –Hierarchical organization and emergent properties –Regulatory capacity leading to homeostasis –Diversity and similarity –Medium for life: water (H 2 O) as a solvent –Information Processing

4. Properties of Living Systems: Order Define “random” Define “order” in an abiotic system Why is “order” and important property” Examples of “order” in living systems –Level of a biomolecule –Level of the cell –Level of the organelle –Level of an ecosystem Relate to hierarchical

5. Properties of Living Systems: Reproduction Define “reproduction” in abiotic terms –E.g., fire, crystals Define “reproduction” in biotic terms –Why is it important property of living systems? Examples in living systems –Microbes (fission) –Cells (mitosis) –Whole organisms Donkey

6. Properties of Living Systems: Growth and Development Define “growth” Define “development” Why are “growth and development” important properties of living systems Examples in living systems –Organisms grow –Organisms develop Examples in abiotic systems –Ice crystals –Fire

7. Properties of Living Systems: Energy Use Definitions –Energy capture Autotrophs (photoautotrophs, chemoautotrophs) Heterotrophs (saprovores, carnivores, omnivores, etc.) –Energy utilization (1 st and 2 nd Laws of Thermodynamics) –Energy storage Chemical bonds (covalent C-C bonds) and exothermic reactions ATP (adenosine triphosphate) and ADP (adenosine diphosphate) –Energy dissipation (2 nd Law of Thermodynamics) Why is “energy use” and important property of living systems?

8. Properties of Living Systems: Response to the Environment Define an “open” versus “closed” system –Interaction with the environment –Stimulus followed by a response Why is “response to the environment” an important property? Examples in living systems –Leaf orientation to the sun –Eyes –Ears

9. Properties of Living Systems: Evolution and Adaptation Define “evolution” Define “adaptation” Why is “evolution and adaptation” an important property in living systems? Examples of evolution in living systems –Macroscale: origin of species and taxa –Microscale: microbes resistant to antibiotics moths resistant to air pollution Examples of adaptation –Articulation of the joints in animals –Planar structure of leaves

10. Properties of Living Systems: Hierarchical Organization Define “hierarchical organization” –diagram of atoms to biomolecules to organelles to cells to tissues, etc. Define “emergent properties” –Emergence of “novel and unanticipated” properties with each step of hierarchy Examples in living systems –Hierarchy –Emergent properties

11. Properties of Living Systems: Regulatory Capacity Define “regulatory capacity” –Relate to open systems Define “homeostasis” –Role of feedbacks (positive and negative) and cybernetics Why is “regulatory capacity and homeostasis” and important property of living systems? Examples –Molecular biology: gene regulation –Biochemistry: enzymes –Organisms: temperature –Globe: “Parable of the Daiseyworld”

12. Properties of Living Systems: Diversity and Similarity Define “diversity” –Hallmark of all life (1.5 M known species; 100 M expected) Define “similarity” –Hallmark of all life Why are “diversity and similarity” important properties of living systems? Examples of similarity Biochemistry Structure and Morphology DNA and RNA

13. Properties of Living Systems: Medium for Metabolism Define a “medium for metabolism” and why an important property of living systems? Role of “water” as medium –Physical properties Abundance in universe, state as a f unction of temperature, freezing properties –Chemical properties Bonding, polarity, diffusion, osmosis

14. Properties of Living Systems: Information Define “information” and relate to order Why is “information” an important property of living systems” Necessary states of “information” –Storage –Translation –Template/Copying –Correcting (spell check) Examples –DNA –RNA

15. Astrobiology: The Nature of Life (Chapter 3) Properties/Characteristics of Living Systems Evolution as a Unifying Theme Structural Features of Living Systems Biochemical and Molecular Features of Living Systems Instructional Features of Living Systems Evolution as a Unifying Theme Extremophiles on Earth and Elsewhere Define Life

16. Evolution as a Unifying Theme Darwin’s Origin of Species (1850) –Observations while on the HMS Beagle –Model: Evolution Individuals vary in their fitness in the environment Struggle for existence and survival of the most fit Origin of species via incremental changes in form and function (relate back to observation while on the Beagle) Link to Mendel and the Particulate Model of Inheritance (1860’s) Link to Watson and Crick (1956) and the discovery of DNA Examples of evolution in action Significance of evolution as a theory in Biology

17. Structural Features of Living Systems Ubiquitous nature of “cells” and its hierarchy –Physical, chemical and biological basis for a cell (adaptation) –Suggestion of a common progenitor/ancestor –Physical dimensions of a cell (maximum size) Ubiquitous nature of “organelle” –Efficacy of metabolism (random) –Diversity of function –Diversity of structure –Similarity of structure

18. Structural Features of Living Systems (continued) Evolution of cell types –Prokaryotes Cell, membranes but no nucleus Examples: bacteria –Eukaryotes Cell, membrane, and nucleus All higher plants and animals

19. Biochemical Features of Living Systems Carbon-based economy –Abundance in the universe –Atomic structure (electrons, protons, etc.) –Chemical properties (bonding) Metabolism –Catabolism and biosynthesis –Energy capture and utilization ATP and ADP

20. Biochemical Features of Living Systems (continued) Biochemicals or Bio-macromolecules –Define polymer again Carbohydrates Lipids Proteins Nucleic Acids

21. Out-of-Class Assignment Define living systems –1 sentence description (clean, concise) –2 page supporting statement of why you selected the key properties that you did and why other were ignored –Due next Thursday –Fare game: discussion but not communal writing Rappateur session (Thursday of next week) –Volunteers (4) for 20 minute session –Template for comparison and discussion