2. 29/08/2003 Midterm Review Meeting Helsinki

3. 29.08.2003Midterm Review Meeting, Helsinki2 Overall Objective Research Infrastructure The establishment of a synergistic European network that bundles and coordinates existing competence in clinically oriented research on Parkinsons disease. Network management (WP 1) – committees voting rules publication policy

4. 29.08.2003Midterm Review Meeting, Helsinki3 Who are we? Neurologists with long-term experience and expertise in movement disorders and clinical research from 11 European countries and an IT- partner

5. 29.08.2003Midterm Review Meeting, Helsinki4 EuroPa: Work Packages Overview x – involved partner, xx – responsible partner, (xx) – in collaboration responsible

6. 29.08.2003Midterm Review Meeting, Helsinki5 What are we aiming for? Recruitment of clinically well described patients - unified clinical documentation - minimal data set (WP 3) - registry Web-data entry system (WP 2) - including data management Main achievement will be a central patient registry Advantage for EuroPa in planning and conducting multinational, multicentre clinical trials (WP 4)

7. 29.08.2003Midterm Review Meeting, Helsinki6 What are we aiming for? Spread of Good Clinical Practice (WP 4) Accelerate the standardization of diagnostic and therapeutic strategies EuroPa is qualified to conduct - epidemiological studies (WP 4) - socio-economical studies (WP 5) with impact on patients, the health care system and the society To raise funds for sustainability (WP 6) Long term goal: clinical research organisation for European multicentre clinical trials

8. 29.08.2003Midterm Review Meeting, Helsinki7 EuroPa: Timetable Reference: EuroPa - Technical Annex Pages: 13-14 EuroPa - Proposal Part B Pages: 18-20

9. 29.08.2003Midterm Review Meeting, Helsinki8 Where are we now? More than half of the project funding period is over We have proceeded within schedule Important milestones have been reached in time Participants increasingly identify themselves with EuroPa Details of project progress will be presented by the work package leaders

10. 29.08.2003Midterm Review Meeting, Helsinki9 Summary Main project achievements so far: Establishment of a functioning management structure Data protection and ethical approvals in most centres Patient registry with web-based data capture is working – on-line About 350 patients have been entered Concept of EuroPa clinical trial and research organisation (CREO) is finalized A call for proposals for the first EuroPa study has just been sent out to all participants Possible organisational forms for EuroPa are under evaluation in order to ensure our sustainability