2. Anatomy and Physiology  Lymph vessels, ducts, and nodes  Protects body from infection  Filters bacterial and nonbacterial products  Prevents waste products from entering circulatory system 2

3. Anatomy and Physiology  Dependent on vascular system  Lymph is clear fluid 3

4. Anatomy and Physiology  Two divisions of lymph system Left lymphatic duct also called thoracic duct Right lymphatic duct drains lymph from head, upper torso, and right arm Rest of body drains through left lymphatic duct 4

5. Anatomy and Physiology  Organs related to lymph system are tonsils, thymus gland, and spleen 5

6. Common Signs and Symptoms  Enlarged lymph glands or nodes, fever, fatigue, and weight loss  Most diseases of lymphatic system related to diseases of other systems  Lymphocytosis - increased WBCs  Lymphcytopenia - decreased WBCs 6

7. Diagnostic Tests  CBC with differential  Lymphangiography - X-ray of lymph system after dye injection  MRI  CT  Biopsy of lymph nodes 7

8. Common Diseases of the Lymphatic System  Lymphadenitis - inflammation of lymph glands characterized by swelling, pain, and tenderness 8

9. Common Diseases of the Lymphatic System  Lymphangiitis - swelling of the lymph vessels due to inflammation caused by strep infections following a trauma Characterized by red streak at bacterial entry extending to area of lymph node 9

10. Common Diseases of the Lymphatic System  Lymphangiitis Other symptoms: fever, chills, malaise, cellulitis Treatment: antibiotics; warm, moist packs; and elevation of affected area 10

11. Common Diseases of the Lymphatic System  Lymphedema Abnormal collection of lymph fluid in extremities Diagnosis confirmed by lymphangiography Treatment includes antibiotics or surgical intervention depending on cause 11

12. Common Diseases of the Lymphatic System  Lymphoma Neoplasms affecting lymphoid tissue Affects normal lymphocyte production leading to impaired immunity Symptoms: night sweats, fever, weight loss Treatment may include chemotherapy, radiation, bone marrow transplantation 12

13. Common Diseases of the Lymphatic System  Mononucleosis Viral infection Somewhat contagious “Kissing disease” 13

14. Rare Diseases  Kawasaki Disease  Mucocutaneous lymph node syndrome 14

15. Rare Diseases  Kawasaki Disease  Symptoms Rash similar to scarlet fever Edema of feet and hands Lethargy, congestion 15

16. Rare Diseases  Kawasaki Disease  Symptoms Irritability and fever Dry skin Red lips, tongue, and mucous membrane  Treatment is supportive 16