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* Plus–minus values are means ±SD. † Race was determined by the investigator. ‡ The body-mass index is the weight in kilograms divided by the square of.

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Presentation on theme: "* Plus–minus values are means ±SD. † Race was determined by the investigator. ‡ The body-mass index is the weight in kilograms divided by the square of."— Presentation transcript:

1 * Plus–minus values are means ±SD. † Race was determined by the investigator. ‡ The body-mass index is the weight in kilograms divided by the square of the height in meters. § To convert values for LDL, HDL, and total cholesterol to millimoles per liter, multiply by 0.02586. To convert values for triglycerides to millimoles per liter, multiply by 0.01129. P Barter, et al. NEJM 2007;357:1301-10 The TNT HDL Study: Baseline Characteristics of the Patients According to Quintile of HDL Cholesterol Level at Month 3*

2 The TNT HDL Study: Multivariate Analysis of the Relationship between HDL Cholesterol Levels at Month 3 and the Risk of Major Cardiovascular Events - Results for all patients Philip Barter, et al. N Engl J Med 2007;357:1301-10

3 The TNT HDL Study: Multivariate Analysis of the Relationship between HDL Cholesterol Levels at Month 3 and the Risk of Major Cardiovascular Events - Results for for the 10-mg and 80-mg atorvastatin groups Philip Barter, et al. N Engl J Med 2007;357:1301-10

4 The TNT HDL Study: Multivariate Analysis of the Relationship between Major Cardiovascular Events and Quintiles of HDL Cholesterol Levels Patients were stratified according to specific cutoff points of LDL cholesterol levels in patients receiving statins Philip Barter, et al. N Engl J Med 2007;357:1301-10

5 The TNT HDL Study: Multivariate Analysis of the Relationship between Major Cardiovascular Events and Quintiles of HDL Cholesterol Levels Patients in thelowest stratum of LDL-C during statin treatment (<70 mg per deciliter) were analyzed according to quintile of HDL-C level during treatment Philip Barter, et al. N Engl J Med 2007;357:1301-10

6 The TNT HDL Study: Relationship between Major Cardiovascular Events and Ratio of LDL Cholesterol to HDL Cholesterol at Month 3 Philip Barter, et al. N Engl J Med 2007;357:1301-10

7 The TNT HDL Study: Relationship between Major Cardiovascular Events and Ratio of Total Cholesterol to HDL Cholesterol at Month 3 Philip Barter, et al. N Engl J Med 2007;357:1301-10

8 The TNT HDL Study: Relationship between HDL Cholesterol Levels and the Risk of Major Cardiovascular Events Philip Barter, et al. N Engl J Med 2007;357:1301-10


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