1. Lives Saved Tool (LIST): What is modeled? By: Ingrid Friberg Updated May 2010

2. Risk Factors

3. Multiple micronutrient supplementation IUGR Balanced energy supplementation IPTp

4. Water connection in the home Diarrheal incidence Improved H 2 O source within 30 minutes Improved excreta disposal (latrine, toilet) Hand washing with soap Hygienic disposal of children’s stools

5. Stunting Zinc Diarrhea incidence IUGR Complementary Feeding Complementary feeding education and/or supplementation

6. Wasting Therapeutic Feeding

7. Mortality

8. Tetanus Mortality Disease Specific Treatments Disease Specific Preventions Risk factors Tetanus toxoid Clean delivery (home) Essential childbirth care for all women (including BEmOC and CEmOC)

9. IUGR Asphyxia Mortality Disease Specific Treatments Disease Specific Preventions Risk factors Neonatal resuscitation Essential childbirth care for all women (including BEmOC and CEmOC) Full supportive care (oxygen, iv fluids, antibiotics, etc.)

10. Prematurity Mortality Disease Specific Treatments Disease Specific Preventions Risk factors Full supportive care (oxygen, iv fluids, antibiotics, etc.) Newborn resuscitation Essential childbirth care for all women (including BEmOC and CEmOC) Kangaroo mother care Preventive post natal care (healthy practices and illness detection) Antibiotics for pPRoM Antenatal corticosteroids

11. IUGR Neonatal Diarrheal Mortality ORS Disease Specific Treatments Disease Specific Preventions Risk factors Breast Feeding Promotion

12. Neonatal Sepsis/ Pneumonia Mortality Breast Feeding Prevalence IUGR Breast Feeding Promotion Essential childbirth care for all women (including BEmOC and CEmOC) Full supportive care (oxygen, iv fluids, antibiotics, etc.) Disease Specific Treatments Disease Specific Preventions Risk factors Oral antibiotics Antibiotics for pPRoM Preventive post natal care (healthy practices and illness detection) Syphilis detection and treatment Clean delivery (home) Injectable antibiotics

13. Congenital Anomaly Mortality Disease Specific Treatments Disease Specific Preventions Risk factors Periconceptual folic acid supplementation or fortification

14. Neonatal Other Mortality Disease Specific Treatments Disease Specific Preventions Risk factors Full supportive care (oxygen, iv fluids, antibiotics, etc.)

15. Malaria Mortality Disease Specific Treatments Disease Specific Preventions Risk factors ITNs Antimalarials Stunting Wasting

16. Measles Mortality Disease Specific Treatments Disease Specific Preventions Risk factors Vitamin A Stunting Measles vaccine Wasting

17. Pneumonia Mortality Breast Feeding Promotion Stunting Oral antibiotics Disease Specific Treatments Disease Specific Preventions Risk factors Pneumococcal vaccine Hib vaccine Zinc Wasting

18. Pertussis Mortality DPT Oral antibiotics Disease Specific Treatments Disease Specific Preventions Risk factors Zinc

19. Meningitis Mortality Disease Specific Treatments Disease Specific Preventions Risk factors Pneumococcal vaccine Hib vaccine

20. Stunting Breast Feeding Promotion Post-Neonatal Diarrheal Mortality Vitamin A Zinc Disease Specific Treatments Disease Specific Preventions Risk factors Antibiotics for dysentery ORS Rotavirus vaccine Zinc Water connection in the home or Improved H 2 O source within 30 minutes Improved excreta disposal (latrine, toilet) Hand washing with soap Hygienic disposal of children’s stools Wasting

21. AIDS Mortality Disease Specific Treatments Disease Specific Preventions Risk factors Cotrimoxizole Infant Feeding (exclusive breast, mixed breast, replacement) Child ART PMTCT (neviripine, 2ARV or 3ARV for prevention, 3ARV for treatment)

22. Complete diagram For Post Neonatal diarrhea only

23. Stunting Post-Neonatal Diarrheal Mortality Rotavirus vaccine Vitamin A Zinc Water/Sanitation Zinc Antibiotics for dysentery ORS Disease Specific Treatments Disease Specific Preventions Risk factors IUGR Syphilis detection and treatment IPTp Maternal energy and/or micronutrient supplementation Zinc Complementary Feeding Complementary feeding education and/or supplementation Diarrhea incidence Improved H 2 O source within 30 minutes Hand washing with soap Water connection in the home Improved excreta disposal (latrine, toilet) Hygienic disposal of children’s stools Distal Factors Breast Feeding Breast Feeding Promotion Wasting Therapeutic Feeding

24. Maternal Mortality

25. Antepartum Hemorrhage Disease Specific Treatments Disease Specific Preventions Risk factors Access to BEmOC Access to CEmOC

26. Postpartum hemorrhage Disease Specific Treatments Disease Specific Preventions Risk factors Active Management of the 3 rd stage of labor Access to BEmOC Access to CEmOC

27. Hypertensive Diseases of Pregnancy Disease Specific Treatments Disease Specific Preventions Risk factors Pre-eclampsia case management with MgSO4 Calcium supplementation Access to CEmOC Management of eclampsia with MgSO4

28. Sepsis Mortality Disease Specific Treatments Disease Specific Preventions Risk factors Sepsis Case management Antibiotics for pPRoM Clean delivery (home) Essential childbirth care for all women (including BEmOC and CEmOC)

29. Post abortion case management Safe abortion (including D&C, vacuum aspiration, medical) Abortion-related Mortality

30. Obstructed labor Disease Specific Treatments Disease Specific Preventions Risk factors Access to BEmOC Access to CEmOC

31. Ectopic pregnancy Disease Specific Treatments Disease Specific Preventions Risk factors Case management of ectopic pregnancy at BEmOC level Case management of ectopic pregnancy at CEmOC level

32. Other direct causes of mortality Disease Specific Treatments Disease Specific Preventions Risk factors

33. Maternal Malaria mortality Disease Specific Treatments Disease Specific Preventions Risk factors Case management of malaria during pregnancy IPTp

34. Other indirect causes of mortality Disease Specific Treatments Disease Specific Preventions Risk factors Tetanus toxoid

35. Notes on Maternal Mortality Modelling Anemia –Too much confounding to use as a risk factor currently Age of mother –Has not yet been considered in way to separate the individual causes of mortality