2. 1990-1996 University of Nebraska-Lincoln PhD. in Biochemistry Protein synthesis initiation in eukaryotic system 1997-2001 Vanderbilt University School of Medicine, Nashville Research Fellow Epidermal Growth Factor (EGF) mediated signal transduction 2001-2002 Cellomics Inc., Pittsburgh Knowledge Engineer 2002- 2006 Information Specialist in Molecular Biology and Genetics HSLS, University of Pittsburgh Ansuman Chattopadhyay, Ph.D. ansuman@pitt.edu 2006- Present Head, Molecular Biology Information Service HSLS, University of Pittsburgh http://www.hsls.pitt.edu/molbio

3. Genomic achievements since the Human Genome Project http://www.hsls.pitt.edu/molbio

4. Progress in Genomics Source: Eric Green; HGP10 Symposium http://www.hsls.pitt.edu/molbio

5. DNA Sequencing Cost http://www.hsls.pitt.edu/molbio

6. Big DATA Biology http://www.hsls.pitt.edu/molbio

7. Growth of PubMed Citations Lu et al. Database (Oxford). 2011: baq036 266 K Breast Cancer 104K Schizophrenia 9.9K BRCA1 67K. p53 Aug 20 th 2013 http://www.hsls.pitt.edu/molbio

9. What are Browser Enhancers ? Bookmarklets : bookmarks stored in a web browser that contains JavaScript commands to extend the browser's functionality. a bookmarklet might allow the user to select text on a page, click the bookmarklet, and be presented with a search engine results page for the search term selected. Wikipedia

10. Example : Library Proxy Server Bookmarklets

11. Example: Mendeley’s Web Importer

13. Molecular Biology Information Service License Commercial Software Workshops One-on-one consultations http://www.hsls.pitt.edu/molbio Bioinformatics

14. Challenges for Biomedical Scientists 5669 Journals 23 million Citations Molecular Databases Microarray NGS Tech GWAS Cancer Genome High Throughput Technologies

15. Challenges for Biomedical Scientists

16. how is it calculated ? what is its function ? what is its structure? Challenges for Biomedical Scientists

17. InfoBoosters www.hsls.pitt.edu/infoboosters

18. InfoBoosters

20. Infoboosters

22. InfoBoosters How is it calculated ? What is its function ? What is its structure?

23. Data Integration InfoBoosters

25. Create Your Own InfoBooster WWW.hsls.pitt.edu/infoboosters

26. InfoBooster Generator Clinical Trials.gov

27. InfoBooster Generator Go to the Clinical Trials.gov Website and do a search with a one-word search term, such as asthma 1 1

28. InfoBooster Generator COPY the URL from the search result page 2 2

29. InfoBooster Generator 3 3 4 4 5 5 WWW.hsls.pitt.edu/molbio/infoboosters

30. InfoBooster Generator

32. WWW.hsls.pitt.edu/infoboosters

33. InfoBooster Generator

34. InfoBoosters Pros 1.SIMPLE— Easy to use, create, & install 2.UNIVERSAL— Compatible w/most OS & browsers 3.SEAMLESS— Integrates published lit & other databases

35. Thank you! Any questions? Ansuman Chattopadhyay ansuman@pitt.edu http://www.hsls.pitt.edu/guides/genetics