1. BPA, Baby Bottles and prevention of cancer Dr Carl Albrecht Head of Research 11 August 2010

2. What is this all about? Clash of ideas

3. What are the opposing ideas? Pro-BPA BPA is a valuable chemical, used widely, and poses no health danger to mankind Anti-BPA BPA is a dangerous chemical that should be banned, especially where it is a contamination threat to babies

4. Bisphenol A (BPA) is a man- made chemical Small Symmetric White powder

5. BPA binds to oestrogen receptor

6. BPA + Order = Chaos (Cancer) Highly regulated process Unregulated, haphazard process BPA is an EDC Endocrine Disrupting Compound Happens at very low concentrations –ng/ml

7. DES was given to pregnant women rather than BPA (because it is more active) BPA – Bisphenol ADES - Diethylstibesterol DES was given to 7 million pregnant women for 40 years to prevent miscarriages before it was discovered that DES causes vaginal cancer in the daughters Note how similar BPA and DES are.

8. Effect of a low dose of BPA on breast tissue Control milk duct in mouse breast tissue Mice treated with 25 ng BPA/kg body weight per day 25 ng is 1000-times lower than the FDA safety limit of 25 ug.

9. 92% Americans have BPA in their blood. BPA has been linked to: Increased breast cancer risk Increased prostate cancer risk Early puberty Diabetes Brain dysfunction Thyroid dysfunction Heart disease Infertility in males and females Obesity 25 % of all cancers

10. Conclusion Endocrine disrupting compounds such as DES and BPA (proven and possible cancer threat respectively) must be avoided especially during pregnancy and in 0-3 year old children

11. The danger of man-made endocrine disrupting compounds – “a spanner in the works”. Endocrine Disrupting Compounds LIVING SYSTEMS Chaos …cancer

12. POLYCARBONATE ENTERS THE PICTURE Heat resistant Impact resistant Shatterproof Clear Easily worked Easily moulded Easily thermoformed Discovered that BPA-carbonates when strung together form polycarbonate.

13. Anatomy of Polycarbonate BPA carbonate Polycarbonate Free BPA - plasticiser

14. Other items where polycarbonate or BPA is used

15. The Penny Drops….there is BPA in the baby bottle! The Baby Bottle seems so innocent!

16. World-wide rejection of BPA in Baby Bottles Canada Denmark France Various US States PC

17. Why are children (0-3 yrs) more susceptible to BPA? 1. Brains still developing 2. Lack enzymes to inactivate BPA 3. Eat ten-times more than adults per day per body weight than adults

18. Is the Baby Bottle the Tipping Point against man-made chemical carcinogens?

19. Summary CANSA has studied the pro- and anti-BPA scientific evidence over the past three years and is convinced that BPA, which is hormonally active, poses a threat to human health - specifically by increasing the risk of breast or prostate cancer In order to reduce this increased risk CANSA supports reasonable processes to significantly limit exposure to BPA - especially of pregnant women and our babies who are more vulnerable One such process is to replace polycarbonate baby bottles containing BPA with BPA-free bottles

20. No need to trash the world – trash BPA Baby Bottles

21. CANSA is a watchdog and the Smart Choice logo helps to educate the public. Placing the CANSA Smart Choice logo on BPA- Free baby bottles makes good sense

22. Thank You