1. Lesson 4

2.  Describe the structure of an amino acid  Describe the formation and breakage of peptide bonds  Explain the term primary structure

3.  Draw the structure of a protein and label it in as much detail as you can

4.  Use the diagram of the amino acid to make a model using molymods

5. R Group Acid Group Amino Group

6. Valine Phenylalanine

7. + H 2 0 Condensation Reaction Hydrolysis Reaction Peptide Bond

8.  Make another model of an amino acid to make a model using of peptide bond formation

9.  The function of each protein is determined by its structure  A protein’s structure is firstly determined by its amino acid sequence

10.  The specific sequence of amino acids that make up a protein

11.  DNA strands code for protein structure  3 bases code for a specific amino acid, this is known as a codon or triplet code  Use the look up table to create a DNA strand that will code for a 10 amino acid protein, it needs to start with Methionine and end with a stop code  Swap with the person next to you  Convert their DNA strand into a polypeptide chain

12.  The covalent bond that forms the peptide bond is strong, it must be broken apart by an enzyme  Enzymes that breakdown proteins are called proteases  Examples of protease activity other than digestion:  Hormone regulation  Ageing P101 in book

13.  Jan 2010 Q4a

14. 1. Draw a results table 2. Add sample to a test tube. 3. Add biuret reagent 4. Identify which sample contains protein 5. What colour is a positive test? What colour is a negative test? Practical Skills: Qualitative Drawing Results Table

15. 1. Add sample to a test tube. 2. Add biuret reagent 3. Positive result shown by lilac

16. MarkComplete? Appropriate column and row headings Ruled rows and columns Separate conclusions and observation columns All tests and results recorded Correct conclusions for all test results

17.  Describe the structure of an amino acid  Describe the formation and breakage of peptide bonds  Explain the term primary structure

18.  Draw the structure of a protein and label it in as much detail as you can

19.  Complete the first part of the summary table