1. Cell Structure & Function Introduction to Cells Eukaryotic Cells Prokarytoic Cells

2. Introduction to Cells l History –Robert Hooke (1600’s) first described cells in thin sections of cork that he examined under microscope –Robert Brown (1820) first to describe that a nucleus seemed to be associated with all cells (at least eukaryotic cells)

3. Introduction to Cells l History (continued) –Theodore Schwann & Matthias Schleiden (1839) advanced cell theory »All organisms are composed of cells »The cell is the basic unit of life »All cells arise from preexisting cells

4. Introduction to Cells l Cell Types –Prokaryotic –Eukaryotic l Sizes –Prokaryotic 0.2 to 2.0 microns –Eukaryotic10 to 100 microns

5. Introduction to Cells l Size Determinants –Cell surface to volume relationships govern cell size –The smaller the cell the more efficiently materials can be transported into and within the cell –Cell must also be large enough to deal with information and metabolic requirements

6. Introduction to Cells

7. l Common Components to All –Plasma membrane – phospholipid bilayer that controls movement of substances into and out of cells –Ribosomes – site of protein synthesis – note ribosomes have both RNA & protein –Cytoplasm –matrix on interior of cell consisting of water soluble proteins and other materials –Nuclear material – DNA/Protein complex that stores information »Prokaryotic – circular »Eukaryotic – linear and in chromosomes

8. Eukaryotic Cells l Eukaryotic Cells –Larger than prokaryotic –More complex than prokaryotic –All multicellular organisms composed of eukaryotic cells –Eukaryotic cells composed of many internal structures called organelles

9. Eukaryotic Cells l Endosymbiotic theory (Lynn Margullis – 1967) l Evidence: –Mitochondria & chloroplasts replicate via binary fision –Mitochondria & chloroplasts have circular DNA –Mitochondria & chloroplasts have 70S (bacterial ribosomes) –Mitochondria & chloroplasts start protein synthesis in the same way as prokaryotic cells –Mitochondria & chloroplasts DNA sequences of similar genes show greater relationships to prokaryotic genes

10. Eukaryotic Cells l Nucleus l Mitochondria l Chloroplast l Endoplasmic reticulum (R & S) l Golgi body l Lysosome l Peroxisome l Centrioles l Vacuoles l Flagella & cilia

11. Eukaryotic Cells

13. l Nucleus –Regulates growth and reproduction of cell –Contains DNA and chromosomes l Nucleolus –Ribosomal RNA synthesis

14. Eukaryotic Cells l Mitochondria –Energy production in cell –Contains its own DNA (circular)

15. Eukaryotic Cells l Endoplasmic reticulum (rough and smooth) –Site of protein synthesis in cells –Start of protein export process –Connected to nuclear pores and Golgi body

16. Eukaryotic Cells l Golgi body –Sorting center for proteins in cell –Produces vesicles which fuse with plasma membrane

17. Eukaryotic Cells l Lysosome –Only in animal cells –Production of intracellular digestive enzymes –Involved with phagocytosis

18. Eukaryotic Cells l Peroxisomes –Peroxisomes are small rounded organelles found free floating in the cell cytoplasm. –Contain at least 50 enzymes and are separated from the cytoplasm by a lipid bilayer single membrane barrier. – Produce hydrogen peroxide which is toxic but is rapidly degraded by catalase

19. Eukaryotic Cells l Flagella & cilia –Involved with motility of cells –Composed of microtubules

20. Eukaryotic Cells l Vacuoles –Found only in plants –Large central organelle in plant cells –Regulates water in plant cells

21. Eukaryotic Cells l Chloroplast –Site of photosynthesis in plant cells –Has own DNA (circular) –Found only in plants

22. Eukaryotic Cells l Endosymbiotic theory (Lynn Margullis – 1967) l Evidence: –Mitochondria & chloroplasts replicate via binary fision –Mitochondria & chloroplasts have circular DNA –Mitochondria & chloroplasts have 70S (bacterial ribosomes) –Mitochondria & chloroplasts start protein synthesis in the same way as prokaryotic cells –Mitochondria & chloroplasts DNA sequences of similar genes show greater relationships to prokaryotic genes