1. 2012 MRL Safety Inspection Pre-Inspection Meeting - Feb 08, 2012

2. Time for general lab clean up, time to get your lab safety up to date. Commonly cited items last year Inspection criteria Common issues and particular things that we’ll be looking for Incidents Time for questions & discussion about: Inspections, LSMs, CHPs, SOPs, Chem. inventories, Incidents, etc. Overview

3. 2011 Safety Inspection: Items cited >20 times Door signs: out of date, hazard sections not completed Cluttered labs/aisles Missing equipment guards, panels Blocked electrical panels Electrical cord placement/routing/condition Lack of first aid kits, spill kits Lack of Lab Safety Manuals, incl. CHPs, SOPs, chemical inventories, emergency procedures & shutdown instructions PPE use, availability (eye protection, lab coats) Chem. storage by compatibility Chem. storage: secondary containment

4. 2011 Safety Inspection: Items cited >20 times Door signs: out of date, hazard sections not completed Cluttered labs/aisles Missing equipment guards, panels Blocked electrical panels Electrical cord placement/routing/condition Lack of first aid kits, spill kits Lack of Lab Safety Manuals, incl. CHPs, SOPs, chemical inventories, emergency procedures & shutdown instructions PPE use, availability (eye protection, lab coats) Chem. storage by compatibility Chem. storage: secondary containment

5. 2011 Safety Inspection: Items cited >20 times Door signs: out of date, hazard sections not completed Cluttered labs/aisles Missing equipment guards, panels Blocked electrical panels Electrical cord placement/routing/condition Lack of first aid kits, spill kits Lack of Lab Safety Manuals, incl. CHPs, SOPs, chemical inventories, emergency procedures & shutdown instructions PPE use, availability (eye protection, lab coats) Chem. storage by compatibility Chem. storage: secondary containment

6. 2011 Safety Inspection: Items cited >20 times Door signs: out of date, hazard sections not completed Cluttered labs/aisles Missing equipment guards, panels Blocked electrical panels Electrical cord placement/routing/condition Lack of first aid kits, spill kits Lack of Lab Safety Manuals, incl. CHPs, SOPs, chemical inventories, emergency procedures & shutdown instructions PPE use, availability (eye protection, lab coats) Chem. storage by compatibility Chem. storage: secondary containment

7. 2011 Safety Inspection: Items cited >20 times Door signs: out of date, hazard sections not completed Cluttered labs/aisles Missing equipment guards, panels Blocked electrical panels Electrical cord placement/routing/condition Lack of first aid kits, spill kits Lack of Lab Safety Manuals, incl. CHPs, SOPs, chemical inventories, emergency procedures & shutdown instructions PPE use, availability (eye protection, lab coats) Chem. storage by compatibility Chem. storage: secondary containment

8. Door signs: out of date, hazard sections not completed Cluttered labs/aisles Missing equipment guards, panels Blocked electrical panels Electrical cord placement/routing/condition Lack of first aid kits, spill kits Lack of Lab Safety Manuals, incl. CHPs, SOPs, chemical inventories, emergency procedures & shutdown instructions PPE use, availability (eye protection, lab coats) Chem. storage by compatibility Chem. storage: secondary containment 2011 Safety Inspection: Items cited >20 times

9. Door signs: out of date, hazard sections not completed Cluttered labs/aisles Missing equipment guards, panels Blocked electrical panels Electrical cord placement/routing/condition Lack of first aid kits, spill kits Lack of Lab Safety Manuals, incl. CHPs, SOPs, chemical inventories, emergency procedures & shutdown instructions PPE use, availability (eye protection, lab coats) Chem. storage by compatibility Chem. storage: secondary containment 2011 Safety Inspection: Items cited >20 times

10. Door signs: out of date, hazard sections not completed Cluttered labs/aisles Missing equipment guards, panels Blocked electrical panelsclearance requirement: 3 feet Electrical cord placement/routing/condition Lack of first aid kits, spill kits Lack of Lab Safety Manuals, incl. CHPs, SOPs, chemical inventories, emergency procedures & shutdown instructions PPE use, availability (eye protection, lab coats) Chem. storage by compatibility Chem. storage: secondary containment

11. 2011 Safety Inspection: Items cited >20 times Door signs: out of date, hazard sections not completed Cluttered labs/aisles Missing equipment guards, panels Blocked electrical panels Electrical cord placement/routing/condition Lack of first aid kits, spill kits Lack of Lab Safety Manuals, incl. CHPs, SOPs, chemical inventories, emergency procedures & shutdown instructions PPE use, availability (eye protection, lab coats) Chem. storage by compatibility Chem. storage: secondary containment

12. 2011 Safety Inspection: Items cited >20 times Door signs: out of date, hazard sections not completed Cluttered labs/aisles Missing equipment guards, panels Blocked electrical panels Electrical cord placement/routing/condition Lack of first aid kits, spill kits Lack of Lab Safety Manuals, incl. CHPs, SOPs, chemical inventories, emergency procedures & shutdown instructions PPE use, availability (eye protection, lab coats) Chem. storage by compatibility Chem. storage: secondary containment

13. 2011 Safety Inspection: Items cited >20 times Door signs: out of date, hazard sections not completed Cluttered labs/aisles Missing equipment guards, panels Blocked electrical panels Electrical cord placement/routing/condition Lack of first aid kits, spill kits Lack of Lab Safety Manuals, incl. CHPs, SOPs, chemical inventories, emergency procedures & shutdown instructions PPE use, availability (eye protection, lab coats) Chem. storage by compatibility Chem. storage: secondary containment

14. 2011 Safety Inspection: Items cited >15 times Door signs: out of date, hazard sections not completed Cluttered labs/aisles Missing equipment guards, panels Blocked electrical panels Electrical cord placement/routing/condition Lack of first aid kits, spill kits Lack of Lab Safety Manuals, incl. CHPs, SOPs, chemical inventories, emergency procedures & shutdown instructions PPE use, availability (eye protection, lab coats, gloves) Chem. storage by compatibility Chem. storage: secondary containmen t

15. 2011 Safety Inspection: Items cited >20 times Door signs: out of date, hazard sections not completed Cluttered labs/aisles Missing equipment guards, panels Blocked electrical panels Electrical cord placement/routing/condition Lack of first aid kits, spill kits Lack of Lab Safety Manuals, incl. CHPs, SOPs, chemical inventories, emergency procedures & shutdown instructions PPE use, availability (eye protection, lab coats) Chem. storage by compatibility Chem. storage – use of secondary containment

16. 2011 Safety Inspection: Items cited >15 times Door signs: out of date, hazard sections not completed Cluttered labs/aisles Missing equipment guards, panels Blocked electrical panels Electrical cord placement/routing/condition Lack of first aid kits, spill kits Lack of Lab Safety Manuals, incl. CHPs, SOPs, chemical inventories, emergency procedures & shutdown instructions PPE use, availability (eye protection, lab coats, gloves) Chem. storage by compatibility Chem. storage: secondary containment Unsecured gas cylinders Improper labeling of chemicals

17. 2011 Safety Inspection: Improvements Less accumulation of waste chemicals before processing for disposal Storage of toxics/carcinogens not used Storage of large quantities when less is sufficient

18. Common issues Particular things that we’ll be looking for…

19. Disposing old equipment Take responsibility to find out if there are any ‘items of concern’ in equipment that you’re going to dispose. Can’t simply throw everything away any more. Toxic materials, such as PCBs, dyes, batteries, etc. must be disposed properly. New State Law: No electronics may be thrown in the trash. If you are unsure, contact us. The safety committee can help.

20. Syringes Considered PIMW* – must not be disposed in trash. Waste transfer station workers can’t tell the difference. Syringes must always be disposed in a Sharps container... Syringes of any material Any part of a syringe (needles, bodies, plungers) Regardless of use includes unused syringes * Potentially Infected Medical Waste Sharps containers & their disposal are free.

21. Alcatel Vacuum pumps Oil-sealed rotary vane vacuum pumps subject to recall. ( See ref. slides)

22. Water lines Water lines must be reinforced tubing. Connections must be clamped. Secured Nylon reinforced PVC

23. Water lines Water lines that aren’t pressurized are exempt but must still be secure. Example: water lines that free-flow into the drain. Secured BadGood

24. Incidents…

25. UCLA fatal tert-butyl lithium fire - Dec, 2008 Very brief summary While dispensing t-BuLi, syringe plunger popped out of syringe body, material splashed onto her clothes. The material ignited. (It’s pyrophoric) Knocked over an open flask of Hexane – which also ignited. Fire ignited her polyester sweater, severely burning her arms and upper torso.

26. UCLA fatal tert-butyl lithium fire - Dec, 2008 Complex case, nonetheless a few basic lessons can be related: PPE! No lab coat worn Amount of material vs. capacity of container 50mL/60mL Unrelated chemicals in work area Know the location of, and use emergency equipment Think about what else you’re wearing: Synthetic materials like polyester described as being “analogous to solid gasoline.”* Don’t take things for granted (more later) Undoubtedly more. * Neal Langerman, founder of Advanced Chemical Safety in an ACS report http://pubs.acs.org/cen/news/87/i04/8704news1.html

27. UCLA fatal tert-butyl lithium fire - Dec, 2008 Consequences: Injuries were fatal Questions of training, hazard identification, lab safety practices, supervision. Felony charges have been filed against UC and against professor http://www.latimes.com/news/local/la-me-1228-ucla-death-20111228,0,7543387.story

28. Texas Tech Nickel hydrazine perchlorate explosion – Jan, 2010 Very brief summary Students synthesized 10 grams of material instead of 100 milligrams max. 5 th year grad student removing ‘lumps’ in 5g portion of the material with a mortar & pestle. Set the materials down and removed goggles. Returned to give it one more stir, neglecting to don goggles. Material exploded, causing the loss of 3 digits on left hand, lacerating right hand, perforating left eye, scratching right eye, etc.

29. Texas Tech Nickel hydrazine perchlorate explosion – Jan, 2010 Complex case, nonetheless a few basic lessons can be related: PPE! Removed eye protection before last ‘stir’ then failed to put it back on. Researcher’s space was disorganized, items not labeled. Conflicts over space, cleanliness, use of chemicals. Students were apparently told there was a 100mg limit – no documentation to support this. No notes taken during the experiment, uncertainty over the material synthesized. Undoubtedly more.

30. Consequences: Injuries Questions of training, supervision Documentation of training and restrictions imposed on students essentially nonexistent. TTU overhauls its safety structure. Acknowledgement that lab standards focus on health and exposure hazards, but physical hazard information is way behind, or missing Texas Tech Nickel hydrazine perchlorate explosion – Jan, 2010 These two incidents focusing attention to lab safety in academia.

31. Seemingly endless, minute safety details make sense and protect researchers, but are not necessarily complete. Familiarity can be the enemy – you do some things every day. Almost inevitably, perception of risk may change, but the risks do not. One of the big challenges in keeping safety measures prominent in the minds of researchers Lessons - in a broad sense.

32. Try not to take things for granted. Reporting of incidents and near misses are a way for everyone to learn. SOP template includes a signature line for documentation of training – this isn’t by chance. Without documentation, essentially no training has occurred in the eyes of investigating bodies. Lessons - in a broad sense.

33. Questions? http://mrl.illinois.edu/safety Inspection calendar:

34. Reference slides…

35. Alcatel Vacuum pumps Affected Models These pumps include models in the ALCATEL PASCAL Series ‐ in sizes from 5 to 21 m3/h (cubic meters per hour). Specific models include: 1005, 1010, 1015, 1021: ‐ including those with "SD" or "C1" suffixes 2005 SD, I, C1, or H1 2010 SD, I, C1, or C2 2015 SD, I, C1, C2, or H1 2021 SD, I, C1, or C2 Affected models all have serial numbers BELOW 408960.

36. UCLA t-BuLi fire http://pubs.acs.org/cen/science/87/8731sci1.html - Includes numerous links for more info. http://pubs.acs.org/cen/news/87/i04/8704news1.html http://www.latimes.com/news/local/la-me-1228-ucla-death- 20111228,0,7543387.story TTU Ni hydrazine perchlorate explosion http://www.csb.gov/investigations/detail.aspx?SID=90&Type=2&pg=1&F_All=y http://cen.acs.org/articles/88/i34/Texas-Tech-Lessons.html Video covering both incidents (and trimethylmercury poisoning incident) http://www.csb.gov/videoroom/detail.aspx?VID=61 * * Well done – recommended (Consider showing it to your group)

37. Long form 1/3

38. Long form 2/3

39. Long form 3/3

40. Office Insp. form

41. Short Form

42. Door sign http://www.drs.illinois.edu/gls/forms/pdf/emergencycontactsign.pdf

43. MRL safety page: http://mrl.illinois.edu/safety e-mail: Safety@mrl.illinois.edu Lab Inspection short form: http://mrl.illinois.edu/sites/default/files/pdfs/ShortFormForLabSelfInspections.pdf Lab inspection full form & instructions: http://mrl.illinois.edu/sites/default/files/pdfs/UofILabSafetyInspectionForm.pdf http://mrl.illinois.edu/sites/default/files/pdfs/UofILabSafetyInspectionFormInstructions.pdf MRL Office inspection form: http://mrl.illinois.edu/sites/default/files/pdfs/2009MRLOfficeInspectionForm.pdf University of Illinois Lab Safety Manual Template: http://www.drs.illinois.edu/factsheets/index.aspx University of Illinois Chemical Hygiene Plan template: http://mrl.illinois.edu/sites/default/files/pdfs/UofICHPNotebook.pdf U of I CHP page: http://www.drs.illinois.edu/css/guidesplans/chyp Blank MRL Chemical Inventory form: http://mrl.illinois.edu/sites/default/files/pdfs/ChemicalInventoryForm-blank.doc University of Illinois Laboratory Door Sign Editable PDF form: http://www.drs.illinois.edu/gls/forms/pdf/emergencycontactsign.pdf Links