1. WG 3: Impact assessment ► Conceptual framework for impact assessment for xenobiotics in the urban water cycle ► Biotests as analytical tool ► Are we measuring the right thing? COST 636 Xenobiotics in the Urban Water Cycle – Vienna 25-27 September 2006 45

2. WG3 in Vienna ► Why biotests? ► Which tests? ► How to perform them? (WET, fractions, in situ) ► Sampling ► Biotest results in a regulatory context ► The TGD-RA paradigm for complex samples ► Links to WFD COST 636 Xenobiotics in the Urban Water Cycle – Vienna 25-27 September 2006 45

3. WG3 in Vienna: Discussion with other WGs  Source tracking – gaining knowledge about composition  Phys-chem interactions – which “form” has XOCs  Treatment efficiency – toxicity before and after cleaning after treatment: Use of biotests  Concentrations – continuous discharge vs. intermittent discharges: Biological effects of pulses  Chemicals vs effects – biotest as screening tools for identification & ranking  extrapolation  Detection vs availability (presence, uptake, effects)  QSARs/QSPRs COST 636 Xenobiotics in the Urban Water Cycle – Vienna 25-27 September 2006 45

4. Action plan 2007-2008: Aims and output of WG3 ► Gaps in knowledge + expertises in WG3 (+other) = new projects ► Output of WG3 = Projects  Research projects  Mobility of HR  Courses COST 636 Xenobiotics in the Urban Water Cycle – Vienna 25-27 September 2006 45

5. Expertises in WG3 45

6. Action plan 2007-2008 ► Plan for 2007  Meeting in March 2007 – in Karlsruhe  Meeting in autumn 2007 – where? ► Activities 2007 & 2008  Themes – 2 meeting/yr  Conceptual framework – building blocks and context COST 636 Xenobiotics in the Urban Water Cycle – Vienna 25-27 September 2006 45

7. Action plan 2007-2008: Themes ► Effects of selected chemicals in WG1/WG4 – which compounds? ► Treatment (solid & aq. waste streams) and relation to effect assessment ► Background concentrations and reference conditions ► The role of impact assessment in urban water management ► Basic definitions in relation to conceptual impacts assessment framework – focus:  Communication and concrete facts  Strategy  Test systems – Fraunhofer Institute (invited speaker?) ► Bioavailability! – Vera distributes document ► Sediments ► How to derive environmental quality criterias  EU vs US vs Canada COST 636 Xenobiotics in the Urban Water Cycle – Vienna 25-27 September 2006 45

8. Action plan 2007-2008: Mobility and dissemination ► Identification of opportunities for exchange of human resources ► Identification of common topics for training courses  Aim  Structure  Target group ► Case scenarios – ”internal short-course” for WG3/4 meeting  Real data  ”a real regulator’s” perspective  Theory in practice  WG interaction!  Task force: Anders, Ivana 1or2, Ralph COST 636 Xenobiotics in the Urban Water Cycle – Vienna 25-27 September 2006 45

9. Action plan 2007-2008: WG3 & WG4 common meeting ► Next meeting:  Chemical analyses vs. Biotest for hazard identification, ranking and risk assessment  Monitoring and the regulatory context – gaps and beyond!  ”The Game of Gaps”  Invited speaker… WFD – in practice & with a chemical perspective COST 636 Xenobiotics in the Urban Water Cycle – Vienna 25-27 September 2006 45