1. Agnes Scott College Department of Chemistry (an American Chemical Society approved program) Program in Biochemistry and Molecular Biology (BMB)

2. Why Major in Chemistry or BMB?  Career Opportunities  Research (industry, biomedical fields)  Academic chemist (biomedical, biological)  Medical school  MD  MD/PhD  Teaching (MAT)  Law school  Library science

3. What do our majors do?  Sara B. – second year graduate student at Northwestern University  DeeDee S. – third year graduate student at Northwestern University  Patrice B. – 2003, Ph.D. Purdue University, Dreyfus Fellow, Ga. Instit. Tech.  Nina T. – Research Fellowship, CDC  Abena F. – Rollin’s School of Public Health  Sara S. – CDC Fellowship in Namibia  Mary F. – 1 st year graduate student at Emory

4. Chemistry Faculty  Doug Fantz, Assistant Professor  Biochemistry, organic chemistry, first year seminar  Lilia Harvey, Associate Professor  Organic chemistry, senior seminar  Ruth Riter, Assistant Professor  Analytical chemistry, introductory chemistry, quantitative analysis, environmental chemistry  Leon Venable, Associate Professor  Introductory chemistry, bioinorganic chemistry, advanced inorganic chemistry  Patrice B., sabbatical replacement for 06-07  Sara Winget, Visiting Professor  Physical chemistry, introductory chemistry

5. Courses of Study  Regular Chemistry Major  ACS (American Chemical Society) Approved Chemistry Major  Chemistry Minor  Biochemistry & Molecular Biology (interdisciplinary major with biology) (interdisciplinary major with biology)

6. Chemistry Curriculum non-ACS degree ClassDescriptionHoursNon-Chem Pre/corequisites 101/101LMatter and Rxns4 102/102LPeriodicity4 201/201LOrganic I4 202/202LOrganic II4 301/301LP. Chem. I4Math 118,119,220(R); Physics 110,111 302P. Chem. II4 311Quant. Chem. Anal.4 312Instrumental4Physics 242,243 (electronics (2 hr each)) 342L/343LPhys. and Inst. Meth.1/1 431/LMod. Inorg.4 VariableAny advanced chem.4 Total Hours42Total hours w/ prereqs62 ; 66(R) ACS certified degree -addition of Biochem. I Minor 2 courses beyond 202

7. BMB Curriculum Courses Required Biology Chemistry BIO 191 : Molecular and Cellular BiologyCHE 101/101L : Fund. Concepts of Matter and Reactions BIO 192 : Genetics and Developmental BiologyCHE 102/102L : Periodicity and Chemical Reactions BIO 316 : Molecular BiologyCHE 201/201L : Organic Chemistry I BIO 300 / CHE 300* : Biochemistry ICHE 202/202L : Organic Chemistry II CHE 300 / BIO 300* : Biochemistry I plus one of the following BIO courses:CHE 301 : Physical Chemistry I CHE 342L : Physical and Instrumental Methods of Exp. I CHE 400 : Biochemistry II BIO 301 : Microbiology BIO 309 : Cells and Tissuesplus one of the following CHE courses: BIO 315 : Genetics BIO 317: Immunology BIO 318 : Developmental BiologyCHE 210 : Bio-inorganic Chemistry CHE 302 : Physical Chemistry II CHE 311 : Quantitative Chemical Analysis * Note: BIO 300 and CHE 300 are cross-listed courses, and either (but not both) can be taken to satisfy the major. ** Note: CHE 301 requires MAT 118 & 119 as well as PHY 110 & 111. Research Requirement

8. Course features  Small classes  Small labs  Labs are taught by Ph.D. chemists  Hands-on access to equipment  Collaborative research opportunities

9. Research Opportunities  Research with chemistry and biology faculty members  Interdisciplinary research with faculty from other disciplines  Research collaborations (interdisciplinary or strictly chemical) with scientists at other institutions

10. Doug Fantz- Biochemistry  Investigation of the Ras pathway using C. elegans as a model organism C. elegans lin-3 let-23 sem-5 let-60 lin-45 mek-2 mpk-1 lin-1 1˚ vulval fates H. sapiens EGF EGFR GRB2 RAS RAF MAPKK MAPK Elk-1 proliferation

11. Lilia Harvey – Organic Chemistry Photochemistry of Alpha-(Aryloxy) Acetophenone and Derivatives

12. Ruth E. Riter – Analytical Chemistry Photoinduced Electron Transfer Across Reverse Micellar Interfaces

13. T. Leon Venable – Inorganic Chemistry (1)Synthesis and Characterization of Ru-B Clusters as Potential Cancer Therapy Agents (2)Synthesis and Characterization of Cu-Amino Acid Complexes

14. Sarah Winget – Physical Chemistry - use of vibrational spectroscopy to design and characterize surface and interface chemistries SEM image from Zhao et al, International Journal of Nanoscience, 1, (2002) 87-97

15. New Equipment  ~ $750,000 worth of new equipment and equipment upgrades  Spectroscopy: UV-VIS, FT-IR, Laser, Raman  Separatory/analytical: GC, GC/MS, HPLC, CE  Structural/analytical: NMR – 400 MHz  Probe microscopy: STM/AFM  Data acquisition

16. Scanning Tunneling Microscopy STM / Atomic Force Microscopy AFM 2.5 Å STM Image of Graphite Molecular Model of Graphite

17. NMR Nuclear Magnetic Resonance –Same process as used in MRI (Magnetic Resonance Imaging) 400 MHz –Greater sensitivity –Can study proteins –Other resonances C-13, B-11, P-31, etc.

18. Student Affiliates of the American Chemical Society  Active student chemistry organization  Four-time national award winners for chapter activities  Outreach activities  Tutoring  Chemistry shows & demonstrations  Campus open-house activities

19. Questions?  Dr. Douglas Fantz  SC301W  x-5067  dfantz@agnesscott.edu