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Chapter 11: Introduction to Genetics

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1 Chapter 11: Introduction to Genetics
Section 11.2

2 Probability Probability is the likelihood that something will happen
Example: Flipping a coin Example: Choosing the right question on a multiple choice test Probability can be used to predict traits

3 Dominant vs. Recessive Alleles are represented by letters
Dominant alleles are represented by a capital letter R Recessive traits are represented by a lower case letter r Dominant alleles are expressed over recessive alleles If you have to alleles together the dominant one will always be expressed or “visable” Example: Height Example: Brown hair

4 Key Words Homozygous: organisms that have 2 identical alleles for a particular gene Homozygous dominant (2 dominant alleles) RR Homozygous recessive (2 recessive alleles) rr Heterzgous: organisms that have 2 different alleles Have a dominant allele (written first) and a recessive allele Rr

5 Practice Label the following as either homozygous or heterozygous EE
Tt Zz YY Yy pp bb NN

6 Key Words Phenotype: physical expression of alleles, the traits, “what you see” Genotype: genetic make-up, you cannot see it, this is the letter representation of the phenotype YY, Ff, ff

7 Example Phenotype: Brown Genotype Bb

8 Practice In people, brown eyes (B) are dominant to blue (b), from the following phenotypes identify possible genotypes: bb BB or Bb BB or Bb bb

9 What are your traits? Curley (H) hair is dominant to straight (h)
Widow’s peak (W) is dominant to no widow’s peak (w) Free ear lobes (F) are dominant to attached ear lobes (f) Hair Widow’s Peak Ear lobes Phenotype Straight Yes Free Possible Genotypes hh WW or Ww FF or Ff

10 Punnet Squares Punnet Squares: use probability to help predict genotypes and phenotype combinations (ratios) in genetic crosses Monohybrid Cross: examine the inheritance of only one specific trait.

11 Completeing Punnet Squares
Start with the Parents: Find the genotype of the parents Figure out the Gametes: Determine the alleles that each parent could pass on to their offspring Set-up the Table: Draw the Punnet Square and place the alleles and parents on the top and the left side of the square Complete the Punnet Square: Fill in the table with offspring’s possible genotypes Interpret the results

12 Step 1: Start with Parents
Long fins (L) in fish are dominant to short (l). You are breeding a homozygous dominant long fin male to a homozygous recessive short fin female. What are the possible genotypes of the F1 offspring? What are the genotypes of the parents Male: LL Female: ll

13 Step 2: Figure out the gametes
What alleles can the male and female possibly give to their offspring? Male Genotype: LL Can give an L allele or an L allele Female Genotype: ll Can give an l allele or an l allele LL L L ll l l

14 Step 3: Set up the Punnet Square
L L l

15 Step 4: Fill in Punnet Square

16 Step 4: Completed Punnet Square
L L l Ll Ll Ll Ll

17 Step 5: Interpret Results
What were the possible genotypes from the cross? Ll (heterozygous dominant) What are the possible phenotypes from the cross? All offspring will have long fins

18 Step 5: Interpret Results
What is the probability that the genotype will be Ll? 4/4 = 100% What is the probability that the genotype will be ll? 0/4 = 0%

19 Step 5: Interpret the Results
What is the probability that the offspring will have long fins? 4/4 = 100% What is the probability that the offspring will have short fins 0/4=0%

20 Testcross A testcross is a cross between an organism with an unknown genotype and an organism with the recessive phenotype If you have an organism with the dominant phenotype and you need to determine the possible genotype you can perform a test cross. If you cross your Dominant organism with a recessive and produce recessive offspring you know the unknown organism must be heterozygous. If no recessive offspring are produced can you be sure of the genotype of the unknown organism? NO

21 Testcross Example Cattle are either horned or polled (no horns)
Horns are dominant to polled Polled cattle are worth more so want genotypes that carry the polled allele Ranchers will test cross cattle with horns to determine if they are heterozygous or homozygous dominant

22 Questions??????


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