1. 1 Trieste: from Research Projects to Innovation Alberto Steindler – COO eHealth & eGovernment integrated solutions

2. 2 Friuli Venezia Giulia a Region of Excellence 3 Universities (UniTS - UniUD - SISSA) 4 Science & Technology parks Area Science Park the main Italian Scientific campus Friuli Innovazione Polo Tecnologico Pordenone Agemont 30+ Research Centres and International Institutions The FVG Region scores 8.8 researchers out of 1,000 workers ITALY 3.3 EU 5.4 OECD average 6.9 USA 9.6 Japan 10.4

3. 3 TRIESTE City of Science Trieste 38.5 researchers per 1,000 workers University of Trieste SISSA International School for Advanced Studies INAF Astronomical Observatory of Trieste LBM Marine Biological Laboratory ICTP International Centre for Theoretical Physics TWAS Academy of Sciences for the developing world CIB Interuniversity Consortium for Biotechnologies ICGEB International Centre for Genetic Engineering and Biotechnology INFN National Institute for Nuclear Physics ICS UNIDO International Centre for Science and High Technology ELETTRA Synchtrotron and Free-electron laser light TASC National Laboratory for Advanced Technology and Nanoscience CNR Institute for the Structure of Matter OGS National Institute for Oceanography and Geophysics This fertile background gave birth to bright examples of excellence in local industry, such as TBS Group

4. 4 Born from the research project ACMAGEST, was established in the ‘80s as an advanced clinical engineering service provider From 2000 it began investing in its growth abroad (esp. EU) widening its range of activities Leader in the services for Medical Equipment & Devices Reference player for e-Health & e-Government systems and solutions HQ - AREA Science Park (Trieste) Operates in 13 countries through over 20 subsidiaries (Austria, Belgium, China, France, Germany, India, UK, Italy, The Netherlands, Portugal, Saudi Arabia, Serbia and Spain) 2200+ highly qualified staff and 197,5M revenues (2011) 330 workshops, 45 Regional operational centres, 25 competence centres 300 laboratories on site, connected to more than 1.000 European and Extra-european Hospitals Listed on the Stock Exchange AIM Italy since 2009 TBS Group

5. 5 TBS Group: from Trieste to Europe… and Beyond PCSGmbH www.pcs.at TBSBETelematic&BiomedicalServicesBvba www.tbsbe.com TBSFRTelematic&BiomedicalServicesSarl www.tbsfr.com SubitecGmbH www.subitec.de MSIMedServInternationalDeutschlandGmbH www.medservinternational.com TBSGroupS.p.A. www.tbsgroup.com EBMSrl www.ebm.it Insiel Mercato S.p.A www.insielmercato.it TeSANS.p.A. www.tesan.it CRIMOItaliaSrl www.crimo.it Caribelsrl www.caribel.it SLT srl www.slt.eu.com SurgicalTechnologiesBV www.surgical.nl TBSPT(STBServiçosTelemáticoseBiomédicosUnipessoalLDA) www.tbspt.com TBSG.B.Telematic&BiomedicalServicesLtd www.tbsgb.com TBS Group, Area Science Park, Trieste Arab Health TBS Saudi SinopharmTBS (China) TBSES(Telematic&BiomedicalServicesSL) www.tbses.com MNE Technologies Private Ltd. www.mneindia.com Tesan Televita srl www.tesantelevita.it

6. 6 Why Innovate? …to create VALUE The WHY of innovation is simple: change is accelerating and we don’t know what’s coming in the future: we must innovate to both prepare for change …and …to make change. CARE (Social and Healthcare Systems) CARE (Social and Healthcare Systems)

7. 7 New products/services New “state of the art” technologies New business models & sales partnerships Intensified cooperation with other businesses and PROs (Public Research Organizations) Enhance culture within the company and outwards: -integrated care -genomics, proteomics, nutrigenomics (and other –omics) and personalized medicine R&D – Overall Aims INNOVATION

8. 8 R&D and INNOVATION in TBS Process innovation to optimize the way in which products and services are created Develop new Telemedicine product & services Develop new medical & bio – informatics solutions for the personalization of medicine (integration of clinical and genetic data) Innovation of processes to better fulfill or even anticipate the requirements of our customer GOAL strengthen our position as a reference player in the markets and as a crucial actor for the new scopes of healthcare - such as the Proactive Medicine - increasing the quality of social and healthcare services provided to the population

9. Our latest and most significant R&D projects CASE EXAMPLES

10. 10 CHRONIUS: management of chronic patients (COPD and Kidney disease) at their home. Several tools such as wearable sensors, and others for lifestyle monitoring, smart clinical decision support system. FEARLESS: detecting potential situation of risk in domestic environment with automatic alarms. Fall alarms, imaging analysis alarms; flood, gas, smoke alarms. Telemedicine … we are not Dreaming only! I-DON’T-FALL: ICT Platform for the prevention and management of falls with personalized solutions for vulnerable patients. HEALTH AT HOME: design and development of a home monitoring system for Chronic Heart Failure patients. IN PISTA: consolidation and extension of support standards to interoperability and integration of social and health information systems.

11. 11 Pharma PHI: integrated molecular data EPR for more personalized and thus efficient drugs. SYMPAR: EPR for the management of neurodegenerative disease protocols (Parkinson). D.NAMICA: IT integrated platform for the personalized medicine (genothypic and phenotypic data). Nutraceutics & Nutrigenomics a path to personalized diet: functional foods and services that improve the health of individuals and reduce the occurrence of disease. Medical & Bio- Informatics

12. 12 phi-Technology: open source platform for the design-generation-implementation of healthcare web applications (process/model driven & sevice oriented architecture) 25+ running contracts Further effects of R&D Telemedicine in the VCO Verbania Cusio Ossola Multi-pathology unified platform The first real-time Telemedicine experience in the Piedmont Region for 300 home patients affected by cancer- diabetes - COPD – Heart Failure. Genotype and Phenotype integrated EPR Telemedicine in the Veneto Region telemonitoring of people who live situations of social and/or health care risk (2,400 users), electronic detection falls (1,200 users), remote monitoring vital signs (1,200 users) now 246 active users. NHS’ Whole System Demonstrator Programme (partecipation in KENT) the largest randomized control trial of telehealth and telecare in the world, involving 6191 patients (diabetes, Heart Failure and COPD) and 238 GP.

13. 13 CLINICAL PATHWAYS: to standardize care processes and improve quality in healthcare. INTEGRATED CARE: to overcome the fragmented delivery of health and social services - more coordinated and integrated forms of care provision (diagnosis, treatment, care, rehabilitation and health promotion). PROACTIVE MEDICINE: shift from reactive medicine (waits for the disease and then provides treatment) Proactive medicine provides a platform for maximizing prevention and aims at treating the root causes of the disease process improving the care of chronic disease and boosting the self care model What’s coming next?

14. 14 R&D plays an important role leveraging the INNOVATION process which is increasingly vital to current and future profits. Innovation brings new or improved products and services to the market place (more customers, more satisfied customers). Innovation allows to participate in new markets. It results in high quality jobs, elevating knowledge among employees. R&D provides a better position to achieve and maintain competitive advantage in the increasingly challenging global market place. R&D IS OUR EYE ON THE FUTURE So… why is R&D so crucial? Our experience…

15. 15 Free reconstruction from “Metamorphose” by M.C. Escher