1. Approach to Paroxysmal Supraventricular Tachycardias
M.V.Jorat MD
1389

2. Definition
Narrow QRS complex supraventricular tachycardia (SVT) is a tachyarrhythmia with a rate more than 100 beats/min and a QRS duration of less than 120 milliseconds.
A narrow QRS complex (<120 msec) reflects rapid activation of the ventricles via the normal His-Purkinje system, which in turn suggests that the arrhythmia originates above or within the atrioventricular (AV) node (ie, a supraventricular tachycardia).

3. Differential Diagnosis of Narrow QRS Complex Tachycardias
Sinus tachycardia
Inappropriate sinus tachycardia
Sinoatrial nodal reentrant tachycardia (SNRT)
Atrial tachycardia (AT)
Multifocal AT
Atrial fibrillation (AF)
Atrial flutter (AFL)
Junctional ectopic tachycardia (JET)
Nonparoxysmal junctional tachycardia
Atrioventricular nodal reentrant tachycardia (AVNRT)
Atrioventricular reentrant tachycardia (AVRT)

5. Sites of origin in Supraventricular Tachyarrhythmias

6. Tachycardia Narrow QRS tachycardia Wide QRS Tachycardia Regular
Irregular
AV node dependent
AV node
independent
AF, AT/AFL with variable AV conduction, multifocal AT
Sinus tachycardia
Junctional tachycardia AT
AFL
AVNRT
AVRT

7. The estimated prevalence in the normal population: 2.25/1,000
Paroxysmal SVT is the term generally applied to intermittent SVT other than AF, AFL, and multifocal AT.
The major causes are:
AVNRT (approximately 50% to 60% of cases),
AVRT (approximately 30% of cases),
and AT (approximately 10% of cases).
The estimated prevalence in the normal population: 2.25/1,000
Incidence: 35/100,000 person-years.
Age: In the absence of structural heart disease it can present at any age but most commonly first presents between ages 12 and 30 years.
Sex: Females/ males: 2

8. Proportion of paroxysmal supraventricular tachycardia mechanism by age
This trend is similar for both gender

9. Initial Evaluation
History, physical examination, and an ECG constitute an appropriate initial evaluation of paroxysmal SVT.
Clinical symptoms are not usually helpful in distinguishing different forms of paroxysmal SVT.
Different methods of electrocardiographic evaluation helps for detection of arrhythmias.

10. Clinical Presentation
Onset and offset:
Abrupt or gradual (warm up and cool down) onset and termination of palpitation
Abnormal automacity or reentrant mechanism
Duration: from minutes to several hours
Commonly is associated with dizziness
Rapid ventricular rates can be associated with:
Dyspnea, weakness, angina, or even frank syncope, and can at times be disabling.
Neck pounding (AVNRT)
Patients often learn to use certain maneuvers such as carotid sinus massage or the Valsalva maneuver to terminate the arrhythmia

11. Physical examination
In patients without structural heart disease, the physical examination is usually remarkable only for a rapid, regular heart rate.
At times, because of the simultaneous contraction of atria and ventricles, cannon A waves can be seen in the jugular venous waveform.
In patients with an AT exhibiting AV block, usually of the Wenckebach type, the ventricular rate is irregular.

12. An echocardiographic examination should be considered in patients with documented sustained SVT to exclude the possibility of structural heart disease.
Exercise testing is less often useful for diagnosis unless the arrhythmia is clearly triggered by exertion.
Invasive EP testing with subsequent catheter ablation may be used for diagnosis and therapy in cases with a clear history of paroxysmal regular palpitations.

13. Clinical history of palpitation
12 lead ECG in normal sinus rhythm
Preexitation
YES NO
Suspected to AVRT
Asses arrhythmia
pattern by clinical history
Irregular
palpitation
Suspected AF,
MAT,
AFL or AT by
variable block
Syncope
Sustained
regular palpitation
Event recorder
and follow up
Refer to Electrophysiologist

14. ELECTROCARDIOGRAPHIC FEATURES

15. Ambulatory 24-hour Holter recording may be used for:
12 lead ECG: 12-lead ECG only during tachycardia can be helpful for defining the mechanism of paroxysmal SVT.
Ambulatory 24-hour Holter recording may be used for:
Documentation of the arrhythmia in patients with frequent (i.e., several episodes per week) but self-terminating tachycardias.
A cardiac event monitor is often more useful than a 24-hour recording in patients with less frequent arrhythmias.
Implantable loop recorders can be helpful in selected cases with rare episodes associated with severe symptoms of hemodynamic instability (e.g., syncope).

16. Heart Monitoring Options
12-Lead
10 Seconds
Holter Monitor
2 Days
Typical Event
Recorder
7 Days
MCOT External
Loop Recorder
30+ Days
ILR
36 Months
ILR = insertable loop recorder
MCOT= mobile cardiac outpatient telemetry 16

17. Typical Wearable ‘Event’ Recorders17

18. External Mobile Cardiac Outpatient Telemetry (MCOT) ECG Recorder
PDA stores ECG data and symptom status. Wireless transmission capability provided.
Patient
Indicates symptoms on PDA.
Abnormal ECG transmitted automatically
Monitor center receives, reviews and transmits data to physician.
Pre-determined ‘urgency’ criteria determine timing of physician alerts
Physician receives and acts upon data as medically appropriate
Cardionet Inc., San Diego, CA 18

19. Insertable Loop Recorder (ILR)
An ECG monitoring system that is implanted subcutaneously
Capable of recording, storing, and if necessary remotely transmitting ECG signals
Patient-activated and/or automatically-activated
Longevity of current ILRs up to 36 months
Indicated for
Patients with unexplained syncope / TLOC
Patients who experience transient symptoms that may suggest a cardiac arrhythmia
Patients at increased risk of cardiac arrhythmias 19

20. Insertable Loop Recorders (ILR)
Reveal® system,
Medtronic Inc., Minneapolis, MN
manual/auto trigger
remote download (CareLink®)
Sleuth®,
Transoma Inc., St Paul, MN
manual/auto trigger
wireless data transmission
Confirm®,
St Jude Medical
St Paul, MN
manual/auto trigger
remote download 20

21. ILR Symptom-Rhythm Correlation: Case Examples
These are examples of ECG recordings obtained by the Reveal® ILR system in 2 symptomatic patients.
The gold standard for determining if a syncope episode is due to an arrhythmia is to record the rhythm during symptoms, ie, symptom-rhythm correlation. The ILR may help rule-in or rule-out arrhythmogenic causes.
These strips depict findings from an ILR interrogation as they appear on the programmer screen. In order to view the event in greater detail, one taps the screen over the ECG of interest.
On-screen calipers are available at every zoom level to measure cycle length in milliseconds or beats per minute.
Note that the ‘A’ represents an auto-activated event; the P indicates when the patient activated the device.
Upper strip: Infra-Hisian AV block: dual chamber pacemaker.
Lower strip: VT and VF: ICD, meds.
Case: 56 year old woman with refractory syncope accompanied with ‘seizures’.
Case: 65 year old man with syncope accompanied by brief retrograde amnesia.
*Medtronic data on file 21

22. Baseline ECG Evaluation

23. Baseline ECG

24. PR dispersion for determination of Preexitation
Tracings from the 12-lead ECG illustrating the principle of PR dispersion.
Lead II has the least pre-excited QRS complex with the longest PR interval (180 ms),
whereas lead V5 is the most pre-excited with the PR interval of 100 ms.
Thus, the PR dispersion was calculated as =80 ms.

25. Use aVR for excludion of preexitation
Four patterns of the QRS complexes in lead V6 and corresponding patterns in lead aVR in the same patient.
Positive delta wave obscuring septal activation.
Isoelectric delta wave resulting in pseudo-septal R wave.
Overt pre-excitation without any isoelectric line between P wave and positive delta wave.
Manifest septal Q wave.

26. Stepwise algorithm to exclude or confirm pre-excitation on a 12-lead ECG
Europace (2010) 12, 119–123

27. Identification of the Atrial Activity during arrhythmia

28. Most SVTs are associated with a regular ventricular rate.
If the rhythm is irregular, the ECG should be scrutinized for discrete atrial activity and for any evidence of a pattern to the irregularity (e.g., grouped beating typical of Wenckebach periodicity).
If the rhythm is irregularly irregular (i.e., no pattern can be detected), the mechanism of the arrhythmia is either multifocal AT or AF.

29. Multifocal AT is an irregularly irregular atrial rhythm characterized by:
More than three different P wave morphologies,
The P waves separated by isoelectric intervals
Varying P-P, R-R, and PR intervals

30. Multifocal Atrial Tachycardia

31. Atrial Fibrillation
AF is characterized by rapid and irregular atrial fibrillatory activity and, in the presence of normal AVN conduction, by an irregularly irregular ventricular response.
P waves cannot be detected in AF, although coarse fibrillatory waves and prominent U waves can sometimes give the appearance of P waves.
The fibrillatory activity sometimes is so fine as to be undetectable.

32. Atrial Fibrillation

33. Chronic AF

34. Paroxysmal AF

35. Naroow QRS tachycardia
Regular tachycardia?
Visible P wave?
AF, AT/AFL with variable AV conduction, multifocal AT
Atrial rate>ventricular rate?
AFL or AT
Analyze RP interval
RP<PR (short RP tachycardia)
RP>PR (long RP tachycardia)
RP interval <70 ms
RP interval>70 ms
AT,
PJRT,
atypical AVNRT
AVRT AVNRT AT
Typical AVNRT

36. Identification of the Atrial Activity
If the patient's rhythm is regular or has a clearly discernible pattern, the ECG should next be assessed for P waves (atrial activity).
The P waves may be easily discernible; however, frequently, comparison with a normal baseline ECG is needed and can reveal a slight alteration in the QRS, ST segment, or T or U waves, suggesting the presence of the P wave.
If the P waves cannot be clearly identified, carotid sinus massage or the administration of intravenous adenosine may help clarify the diagnosis.
These maneuvers may also terminate the SVT.

37. Atrial Flutter

38. P wave in Sinus rhythm and during SVT

39. Carotid Sinus Massage
Temporary decrease in the atrial rate in patients with:
Sinus tachycardia
Automatic AT.
Slowing of AVN conduction and AVN block, which can unmask atrial electrical activity that is, reveal P waves or flutter waves in patients with: AT
AFL

40. CSM during AT

41. Carotid Sinus Massage
3. With some SVTs that require AVN conduction, especially AVNRT and AVRT, the transient slowing of AVN conduction can terminate the arrhythmia by interrupting the reentry circuit;
Less commonly, carotid sinus massage can cause some ATs to slow and terminate.
4. In some cases, no effect is observed.

42. Adenosine Administration
Adenosine results in slowing of the sinus rate and AVN conduction.
In the setting of SVT, the effects of adenosine are similar to those seen with carotid sinus massage.

43. For intravenous adenosine administration, the patient should be supine and should have ECG and blood pressure monitoring.
The drug is administered by rapid intravenous injection over 1 to 2 seconds at a peripheral site, followed by a normal saline flush.
The usual initial dose is 6 mg, with a maximal single dose of 18 mg.
If a central intravenous access site is used, the initial dose should not exceed 3 mg and may be as little as 1 mg.
Adenosine can precipitate AF and AFL because it shortens atrial refractoriness.
In patients with Wolff-Parkinson-White (WPW) syndrome and AF, adenosine can result in a rapid ventricular response that can degenerate into VF.

44. Use of adenosine for diagnosis and termination of regular SVTs, including AVRT, is appropriate as long as close patient observation and preparedness to treat potential complications are maintained.

45. Termination of the Arrhythmia.
Carotid sinus massage or adenosine can terminate the SVT, especially if the rhythm is AVNRT or AVRT.
A continuous ECG tracing should be recorded during these maneuvers, because the response can aid in the diagnosis.
Termination of the tachycardia with a P wave after the last QRS complex is most common in AVRT and typical AVNRT and is rarely seen with AT.
Termination of the tachycardia with a QRS complex is more common with AT, atypical AVNRT, and permanent junctional reciprocating tachycardia (PJRT).
If the tachycardia continues despite development of AV block, the rhythm is almost certainly AT or AFL; AVRT is excluded and AVNRT is very unlikely.

47. Spontaneous Termination during AVRT

48. Atrial Rate
An atrial rate more than 250 beats/min is almost always caused by AFL.
However, overlap exists, and AT and AVRT can occasionally be faster than 250 beats/min.
AVRT tends to be faster than AVNRT and AT.

49. P Wave Morphology P wave morphology identical to sinus P wave:
Sinus tachycardia
Inappropriate sinus tachycardia
Sinoatrial nodal reentrant tachycardia
AT arising close to the region of the sinus node.
An abnormal P wave morphology:
AVNRT (P wave is concentric)
AVRT (P wave can be eccentric or concentric)
AT (P wave can be eccentric or concentric)
AFL (lack of distinct isoelectric baselines between atrial deflections is suggestive of AFL but can also be seen occasionally in AT.

50. The P waves may not be discernible on ECG, which suggests:
Typical AVNRT
Less commonly, AVRT (especially in the presence of bundle branch block [BBB] contralateral to the BT).

51. Characterization of the P/QRS Relationship RP/PR Intervals
SVTs are classified as short or long RP interval SVTs.
In short RP SVTs:
The ECG will show P waves inscribed within the ST-T wave with an RP interval that is less than half the tachycardia RR interval.
Such SVTs include:
Typical AVNRT (most common)
Orthodromic AVRT
AT with prolonged AV conduction
Slow-slow AVNRT
A very short RP interval (less than 70 milliseconds) excludes AVRT.

52. RP Interval

53. Typical AVNRT
Because of the relatively simultaneous atrial and ventricular activation the P wave may distort:
Distort the initial portion of the QRS (Pseudo q) mimicking a q wave in inferior leads
Within the QRS (in apparent)
Distort the terminal portion of the QRS (Pseudo s wave in inferior leads or pseudo r′ in V1

54. AVNRT

56. AVRT

57. Long RP SVTs Include: AT Atypical (fast-slow) AVNRT
AVRT using a slowly conducting AV BT (e.g., PJRT)
If the PR interval during the SVT is shorter than that during normal sinus rhythm (NSR), AT and AVRT are very unlikely, and atypical AVNRT, which is associated with an apparent shortening of the PR interval, is the likely diagnosis.
ATs originating close to the AV junction are also a possibility

58. Long RP Atrial tachycardia

59. PJRT

60. A/V Relationship
SVTs with an A/V ratio of 1 (equal number of atrial and ventricular events) include:
AVNRT
AVRT AT
A/V ratio during the SVT of more than 1 (indicates the presence of AV block and that the ventricles are not required for the SVT circuit)
Excluding AVRT
Suggesting:
AT (most common)
AVNRT (rare)

61. QRS Morphology
The QRS morphology during SVT is usually the same as in NSR.
Functional aberration can occur at rapid rates.
Functional aberration occurs frequently in AF, AFL, and AVRT
Is less common in AT
Is very uncommon in AVNRT

62. 240 msec
270 msec

63. Electrophysiologic Testing

64. Goals of EP test Evaluation of baseline cardiac electrophysiology
Induction of SVT
Mode of initination
Atrial activation sequence
Effect of BBB on arrhythmia
Arrhythmia circuit components
Ablation of arrhythmia

65. Thanks for your attention