1. The Federal Life Sciences Budget: Update and Outlook Matt Hourihan March 25, 2015 for the San Antonio Life Sciences Institute Academy Innovation Forum AAAS R&D Budget and Policy Program http://www.aaas.org/program/rd-budget-and-policy-program http://www.aaas.org/program/rd-budget-and-policy-program

17. Major Funding Priorities for FY16 Advanced Manufacturing Low-carbon energy Climate research and earth observation Agricultural R&D Infrastructure R&D Antibiotic Resistance* Precision Medicine* Discovery Science: Neuroscience; advanced computing COMPETES Agencies R&D: $12.1 billion, +6.6% *New for FY16

18. National Institutes of Health $1 billion increase (+3.3%) Largest relative increases: Alzheimer’s research, translational science New initiatives: Antibiotic Resistance: $100 million for NIAID $200 million for Precision Medicine Large increase for Big Data BRAIN Initiative contribution increases to $135 million Success rate: 19.3%

19. NIAID

20. National Science Foundation Total Budget: +5.2% Highest relative changes: SBE: +7.1%; Engineering: +6.4% EHR: +11.2% New priority areas: Food-water- energy; climate resilience; several cross-agency initiatives boosted BIO: +2.3% Most of the increase in Division of Emerging Frontiers BioMaPS: +12.1% Neuroscience + BRAIN Initiative

22. Defense, Veterans and Energy Defense Dept: 8.3% cut to basic research; mixed bag for medical programs Veterans: 3.2% increase in medical & prosthetics research resources DOE BER: Biological sciences programs trimmed (-1.9%) Focus is on climate research instead

23. Looking Ahead Budget resolutions out…ultimate spending levels still TBD Efforts to get around the caps… American Cures Act and American Innovation Act (Durbin) Would fund several science agencies at 5% above inflation, in excess of sequester levels Accelerating Biomedical Research Act (DeLauro, Mikulski) NIH spending cap exemption Medical Innovation Act (Warren) Would require large drug companies that settle with the government for wrongdoing to pay a small portion of their annual profits for five years for NIH and FDA; the “swear jar” approach War funding? Reserve funds?

27. Looking Ahead: Appropriations Labor, HHS, Education subcommittee (governs NIH) House: Cole; DeLauro Senate: Blunt; Murray Commerce, Justice, Science (NSF) House: Culberson; Fattah Senate: Shelby; Mikulski Energy & Water House: Simpson; Kaptur Senate: Alexander; Feinstein Defense House: Frelinguysen; Visclosky Senate: Cochran; Durbin

28. 3. agency notes R&D STEM

29. For more info… mhouriha@aaas.org 202-326-6607 http://www.aaas.org/program/rd -budget-and-policy-program