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Capsules for Drug Delivery Stepwise Adsorption of Polyelectrolyte Molecules on Dissolvable Templates Final Product: The Polyeelctrolyte Capsule Removal.

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Presentation on theme: "Capsules for Drug Delivery Stepwise Adsorption of Polyelectrolyte Molecules on Dissolvable Templates Final Product: The Polyeelctrolyte Capsule Removal."— Presentation transcript:

1

2 Capsules for Drug Delivery

3 Stepwise Adsorption of Polyelectrolyte Molecules on Dissolvable Templates Final Product: The Polyeelctrolyte Capsule Removal of the Core Fabrication of Polyelectrolytes on Soluble Templates

4 12.719.8 20.6 26.972.6382.6 0 1.4 a b cd ef g h Core Removal

5 Empty Capsules Exclude Polymers

6 Monodisperse Capsules Obtained on Melamin Templates

7 Scanning Electron Microscopy of Capsules - Big and Small

8 10 m   

9 Threeedimensional Replicas of Cells - The Echinocyte The Replica – a Polyelectrolyte Capsule The Template

10 10 m  10 min 1h 4h Adjusting the Permeability by Charging the Wall Permeation of Fluorescein through highly charged walls

11 Filled Capsules Crystals everywhere Only in Capsules

12 The Building Blocks PAH PSS

13 Enzyme Encapsulation by Changing the Wall Permeability 5 m   A FITC-Labelled Protein is encapsulated

14 Osmotic Swelling And Shrinking Layer Mechanics Tailored Polymers for Adsorption und Nucleation Catalysis on Nanopartiicles or Polymeric Catalysts Optical sensors for pH Labelled polymers or Copolymers Microreactors Microsensors Micromechanics Mikrocarriers

15 (a)(b) (c) Capsules with Remains

16 Capsules filled by Synthesis of Polymers inside

17 5 µm Writing on Capsules Reduction of Silver Ions on the Capsule Surface by Laser /

18 Scanning Force Microscopy – The Texture

19 Capsules with Oil inside

20 Coated Colloids – Surface Engineering

21 Reversibel Osmotic Swelling and Shrinking


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