1. Establishment of BUSM and Affiliated Hospitals on the Medical Campus 1848 New England Female Medical College founded 1855 Mass. Homeopathic Hospital founded (1918 Mass. Memorial Hosp.; 1965 University Hosp.) 1866 Boston City Hospital founded 1873NEFMC merges with BU to become Boston University School of Medicine

2. New England Female Medical College Becomes BUSM 1873 Group of 7 MD’s led by Israel Tisdale Talbot expulsed from Mass. Med. Soc. for practicing homeopathy 1873 Talbot negotiates transfer of NEFMC to Boston University 1873 Talbot appointed Dean, BUSM (tenure 1873-1897) 1886 BUSM students allowed to train at BCH under supervision of “regular” physicians 1918BUSM drops association with homeopathy 1930 BU Medical Service is established at BCH

3. Robert Dawson Evans

4. The Bequest of Maria Antoinette Evans 1910 Original gift to fund first building (opened 3/6/1912) 1912 $60,000 for endowment 1913 $100,00 added to endowment 1918 Securities of unspecified value added on Mrs. Evans’ death

5. Mrs. Evans’ Vision Regarding her Bequests The Evans Department of Clinical Research should combine clinical research, research training, and public education Clinical research, clinical care, and teaching should be closely interrelated Hospital beds for patient care should be directed by researchers Laboratories should be restricted to research activities

6. Directors of the Evans Memorial Frank C. Richardson1912 - 1919 Henry M. Pollock1918 - 1930 Allan Rowe1930 - 1934 Reginald Fitz1934 - 1939 Chester S. Keefer1939 - 1961 Robert W. Wilkins1962 - 1972 Norman G. Levinsky1972 - 1997 Joseph Loscalzo1997 - 2005 Thomas Moore (ad interim)2005 - 2006 David Coleman2006 - present

7. Chester Keefer, M.D.

8. Evans 1 1912 Evans 2 1942 Evans 3 1971

9. Dr. Chester Keefer’s Core Faculty Robert Wilkins, M.D. – Hypertension/Cardiology Franz Ingelfinger, M.D. – Gastrointestinal Diseases Charles Burnett, M.D. – Metabolic Diseases Francis Lowell, M.D. – Pulmonary Diseases Louis Weinstein, M.D. – Infectious Diseases Joseph Ross, M.D. – Radioisotopes Arnold Relman, M.D. – Renal Diseases Charles Emerson, M.D. – Hematology

12. Hollander W, Wilkins RW. Chlorothiazide: a new type of drug for the treatment of arterial hypertension. Boston Medical Quarterly 1957; 8(3):69-75. Wilkins RW, Hollander W, Chobanian AV. Chlorothiazide in hypertension. Studies on its mode of action. Annals NY Acad Sci 1958;71:473. Freis ED, Wilson, IM. Potentiating effect of chlorothiazide (Diuril) in combination with antihypertensive agents. Preliminary report. Med Assoc District of Columbia 1957;26:468. Freis ED. Chlorothiazide in hypertensive and normotensive patients. Ann NY Acad Sci 1958;71:450.

14. Selected Faculty Appointments during the Wilkins Tenure Norman G. Levinsky, M.D.Edward A. Alexander, M.D. Jay D. Coffman, M.D.Edgar M. Cathcart, M.D. Alan S. Cohen, M.D.Sidney Cooperband, M.D. Thomas R. Dawber, M.D.Robert Levin, M.D. Robert Donaldson, M.D.Roger Lester, M.D. Jacob Lemman, Jr., M.D.Judith Vaitukaitis, M.D. James Melby, M.D.Leah Lowenstein, M.D. Thomas Ryan, M.D.Donald Small, M.D. Gordon Snider, M.D.Louis Sullivan, M.D. Herbert Teager, M.D.Aram V. Chobanian, M.D.

18. Special Article Annual Discourse – The Boston City Hospital: A Tale of Three “Cities” Ephraim Friedman, M.D. New England Journal of Medicine 1973; 289:503-506

21. Boston VA and BU Medical Service Affiliation of VA with BUSM, HMS and TUSM in 1952 Merger of VA facilities in 1998 to create Boston VA Health Care System. The VA is a key institution for the education of BUSM medical students and residents and helps support more than 100 BUSM faculty. Major BUSM research programs exist currently at the VA

22. Payor Mix for Boston Medical Center (1996 projected) Payment SourcesBCHBUMCHNew BMC Medicare15%44%29% Medicaid27%8%18% BC/BS2%13%7% HMO9%16%12% Other commercial4%9%7% Self-pay and others43%8%27%

26. Growth of Faculty in the Evans Department of Medicine

27. Professors, Department of Medicine Edward Alexander, MDDeborah Cotton, MDAlice Jacobs, MDRichard Saitz, MD Karen Antman, MDWilliam Cruickshank, PhDMichael Klein, MDDavid Salant, MD Caroline Apovian, MDRavin Davidoff, MBBChBernard Kreger, MDJeffrey Samet, MD Gary Balady, MDR. Curtis Ellison, MDNancy Kressin, PhDVaishali Sanchorawala, MD Clinton Baldwin, PhDJerrold Ellner, MDRobert Lafyatis, MDPaul Schroy, MD Emelia Benjamin, MDL. Jack Faling, MDAdam Lerner, MDJohn Schwartz, MD Jeffrey Berman, MDHarrison Farber, MDRobert Levin, MDDavid Seldin, MD, PhD John Bernardo, MDFrancis Farraye, MDRobert Levine, MDRebecca Silliman, MD, PhD Shalender Bhasin, MDLindsay Farrer, PhDSharon Levine, MDRobert Simms, MD Victoria Bolotina, PhDDavid Felson, MDChang-seng Liang, MD, PhDMartha Skinner, MD Lewis Braverman, MDAlan Fine, MDJoseph Mizgerd, ScDAvrum Spira, MD Jerome Brody, MDSusan Fried, PhDThomas Moore, MDMartin Steinberg, MD Wellington Cardoso, MD, PhDRobert Friedman, MDJohn Murphy, PhDMaria Trojanowska, PhD Phyllis Carr, MDIrene Gavras, MDGeorge O‘Connor, MDJoseph Vita, MD Joel Caslowitz, MDHaralambos Gavras, MDJay Orlander, MDKenneth Walsh, PhD Tai Chen, PhDCaroline Genco, PhDThomas Perls, MDDonald Weiner, MD Aram Chobanian, MDJianlin Gong, PhDSusan Perrine-Faller, MDLewis Weintraub, MD Hyon Choi, MD, DPHKevan Hartshorn, MDVasan Ramachandran, MDLee Wetzler, MD David Chui, MDVictora Herrera, MDKatya Ravid, PhDRobert Witzburg, MD Richard Cohen, MDWarren Hershman, MDRahul Ray, PhDVassilis Zannis, PhD David Coleman, MDMichael Holick, MD, PhDSayon Roy, PhDYuging Zhang, DSc Wilson Colucci, MDTien Hsu, PhDNeil Ruderman, MD, DPhil Barbara Corkey, PhDElaine Hylek, MDNelson Ruiz-Opazo, PhD

28. Cardiovascular MedicineHematology/Oncology Wilson S. Colucci, MDDavid Seldin, MD, PhD Clinical Epidemiology Research and Training UnitHypertension David Felson, MD, MPHHaralambos Gavras, MD Computational BiomedicineInfectious Diseases Avrum Spira, MDJerrold J. Ellner, MD Endocrinology, Diabetes, Nutrition, and WeightNephrology Alan Farwell, MD, Interim Section ChiefDavid J. Salant, MD GastroenterologyPreventive Medicine and Epidemiology David Nunes, MD, Interim Section ChiefVasan S. Ramachandran, MD General Internal MedicinePulmonary, Allergy, and Critical Care Medicine Jeffrey H. Samet, MD, MPH,David M. Center, MD Genetics ProgramRheumatology Lindsay A. Farrer, PhDRobert W. Simms, MD GeriatricsVascular Biology Lisa B. Caruso, MD, MPH, Interim Section ChiefRichard A. Cohen, MD Molecular Medicine Herbert T. Cohen, MD Section Chiefs, Department of Medicine