2. Lesson 2 Preventing Communicable Diseases How might behaviors such as wearing appropriate safety equipment help protect you from pathogens?

3. Lesson 2 Lesson Objectives Examine the ways the body protects itself against invading pathogens Develop strategies for caring for your immune system and preventing disease Analyze the ways in which technology has impacted the world in the prevention of communicable diseases Identify health-related community services related to disease prevention In this lesson, you will learn to:

4. Lesson 2 The Body’s Defense System Every day your body is exposed to millions of pathogens. Your body manages to stay free of infection because of your immune system.immune system Physical and chemical barriers protect against a wide variety of invaders. Physical and Chemical Barriers

5. Lesson 2 Physical and Chemical Barriers—The Body’s First Line of Defense The Immune System Few pathogens can pass through the tough layer of dead skin cells that surrounds the body. Tears and saliva contain enzymes that destroy or disable many pathogens. Mucus secreted by mucous membranes carries trapped pathogens to other areas of the body for disposal. Cilia sweep mucus and pathogens to the throat, where they can be swallowed or coughed out. Gastric juice in the stomach destroys many pathogens that enter the body through the nose and mouth.

6. Lesson 2 Defense Strategies of the Immune System The immune system has two major defense strategies. 1.The inflammatory response is general, or nonspecific; it works against all types of pathogens.inflammatory response 2.Specific defenses work against particular pathogens. The Immune System

7. Lesson 2 The Inflammatory Response The purpose of an inflammatory response is to prevent further tissue injury and to halt invading pathogens. In response to invasion by microorganisms and to tissue damage, blood vessels near the site of an injury expand to allow more blood flow to the area. As blood vessels expand, fluid and cells from the bloodstream leak into the area. The collection of fluid and white blood cells causes swelling and pain because of pressure on nerve endings. The Immune System

8. Lesson 2 The Inflammatory Response and Specific Defenses One type of cell that responds to injury is called a phagocyte. Phagocytes engulf pathogens and then destroy them with chemicals.phagocyte Pus, a collection of dead white blood cells and damaged tissue, may collect at the site of inflammation as a response to bacteria. After the pathogens are killed and tissue damage is under control, tissue repair can begin. However, regardless of whether pathogens survive the inflammatory response, specific defenses are activated. This activation is an effort to prevent this same infection from occurring again. The Immune System

9. Lesson 2 Reaction of Specific Defenses to Invasion Specific defenses react to invasion as a result of the body’s ability to recognize certain pathogens and destroy them. During the immune response, certain types of white blood cells react to antigens.antigens Antigens are found on the surfaces of pathogens and in toxins. Macrophages are a type of phagocyte that destroys pathogens by making antigens recognizable to white blood cells. The result of the immune response is immunity.immunity Specific Defenses

10. Lesson 2 The Immune Response Specific Defenses

11. Lesson 2 Lymphocytes There are two types of lymphocytes, T cells and B cells.lymphocytes Helper T cells trigger the production of B cells and killer T cells. Killer T cells attack and destroy infected body cells. Suppressor T cells coordinate the activities of other T cells. They “turn off” or suppress helper T cells when the infection has been cleared. Lymphocytes called B cells produce antibodies. Each B cell is programmed to make one type of antibody, specific to a particular pathogen.antibody Specific Defenses

12. Lesson 2 Memory Cells Some T cells and B cells that have been activated by antigens become memory cells. When memory cells recognize a former invader, the immune system uses antibodies and killer T cells in a quick defense to stop it. If it enters your body again, antibodies will attack the virus immediately, protecting you from becoming ill. The Role of Memory Lymphocytes

13. Lesson 2 Nonspecific Defense Click image to view movie. The Role of Memory Lymphocytes

14. Lesson 2 Active and Passive Immunity Active Immunity The immunity your body develops to protect you from measles and from other diseases is called active immunity. Naturally acquired active immunity develops when your body is exposed to antigens from invading pathogens. Artificially acquired active immunity develops in response to a vaccine.vaccine Passive Immunity The Role of Memory Lymphocytes

15. Lesson 2 Strengthening Your Immune System Follow a sensible eating plan to maintain your overall health and to keep your immune system strong. Get plenty of rest. Get about an hour of physical activity each day. Avoid sharing personal items such as towels, toothbrushes, hairbrushes, and makeup. Avoid tobacco, alcohol, and other drugs. Avoid sexual contact. Keep your immunizations up to date. Care of the Immune System

16. Lesson 2 Vaccines to Aid the Body’s Defenses 1.Live-virus vaccines are made to lose most of their disease-causing properties while stimulating the production of antibodies. 2.Killed-virus vaccines use inactivated pathogens. The organism stimulates an immune response and antibodies are produced. 3.Toxoids are inactivated toxins from pathogens. They can be used against pathogens that are not harmful themselves but produce toxins that cause sickness. 4.New and second-generation vaccines are being developed by scientists using new technologies. Four Types of Vaccines

17. Lesson 2 Vaccination If you are vaccinated against a disease, you can’t spread that disease to others. Some vaccines require more than one dose over time, or “booster shots.” Your family physician and your local health department can advise you on the immunizations you need. Immunization for All

18. Lesson 2 Quick Review Q. Which of the following is NOT a physical and chemical barrier that pathogens encounter when they try to enter the human body? Choose the appropriate option. 1.Skin 2.Tears and saliva 3.Mucous membranes 4.Cortisone

19. Lesson 2 Click Next to attempt another question. A. 4. cortisone Physical and chemical barriers that pathogens encounter when they try to enter the human body do NOT include cortisone. Quick Review - Answer

20. Lesson 2 Quick Review True False Q. The immunity your body develops to protect you from measles and other diseases is called active immunity. You also can be protected from pathogens by passive immunity—receiving antibodies from another person or an animal. Choose the appropriate option.

21. Lesson 2 Click Next to attempt another question. A. True. The immunity your body develops to protect you from measles and other diseases is called active immunity. You also can be protected from pathogens by passive immunity—receiving antibodies from another person or an animal. Quick Review - Answer

22. Lesson 2 Quick Review True False Q. Vaccines have influenced the health status of individuals, families, communities, and the whole world. Choose the appropriate option.

23. Lesson 2 Click Next to attempt another question. A. True. Vaccines have influenced the health status of individuals, families, communities, and the whole world. Quick Review - Answer

24. Lesson 2 End of Lesson 2 Click Home to view the Main menu.

25. Lesson 2 Active and Passive Immunity Passive immunity is receiving antibodies from another person or an animal. Natural passive immunity occurs when antibodies pass from mother to child during pregnancy or while nursing. Artificial passive immunity results from the injection of antibodies produced by an animal or a human who is immune to the disease. Active ImmunityPassive Immunity The Role of Memory Lymphocytes

26. Lesson 2 The Body’s Defense System Every day your body is exposed to millions of pathogens. Your body manages to stay free of infection because of your immune system.immune system Physical and chemical barriers protect against a wide variety of invaders. The immune system is a network of cells, tissues, organs, and chemicals that fights off pathogens. Physical and Chemical Barriers

27. Lesson 2 Defense Strategies of the Immune System The immune system has two major defense strategies. 1.The inflammatory response is general, or nonspecific; it works against all types of pathogens.inflammatory response 2.Specific defenses work against particular pathogens. The inflammatory response is a reaction to tissue damage caused by injury or infection. The Immune System

28. Lesson 2 One type of cell that responds to injury is called a phagocyte. Phagocytes engulf pathogens and then destroy them with chemicals.phagocyte Pus, a collection of dead white blood cells and damaged tissue, may collect at the site of inflammation as a response to bacteria. After the pathogens are killed and tissue damage is under control, tissue repair can begin. However, regardless of whether pathogens survive the inflammatory response, specific defenses are activated. This activation is an effort to prevent this same infection from occurring again. The Inflammatory Response and Specific Defenses A phagocyte is a white blood cell that attacks invading pathogens. The Immune System

29. Lesson 2 Reaction of Specific Defenses to Invasion Specific defenses react to invasion as a result of the body’s ability to recognize certain pathogens and destroy them. During the immune response, certain types of white blood cells react to antigens.antigens Antigens are found on the surfaces of pathogens and in toxins. Macrophages are a type of phagocyte that destroys pathogens by making antigens recognizable to white blood cells. The result of the immune response is immunity.immunity An antigen is a substance that is capable of triggering an immune response. Specific Defenses

30. Lesson 2 Reaction of Specific Defenses to Invasion Specific defenses react to invasion as a result of the body’s ability to recognize certain pathogens and destroy them. During the immune response, certain types of white blood cells react to antigens.antigens Antigens are found on the surfaces of pathogens and in toxins. Macrophages are a type of phagocyte that destroys pathogens by making antigens recognizable to white blood cells. The result of the immune response is immunity.immunity Immunity is the state of being protected against a particular disease. Specific Defenses

31. Lesson 2 Lymphocytes There are two types of lymphocytes, T cells and B cells. Helper T cells trigger the production of B cells and killer T cells. Killer T cells attack and destroy infected body cells. Suppressor T cells coordinate the activities of other T cells. They “turn off” or suppress helper T cells when the infection has been cleared. Lymphocytes called B cells produce antibodies. Each B cell is programmed to make one type of antibody, specific to a particular pathogen. A lymphocyte is a specialized white blood cells that provide the body with immunity. Specific Defenses

32. Lesson 2 Lymphocytes There are two types of lymphocytes, T cells and B cells. Helper T cells trigger the production of B cells and killer T cells. Killer T cells attack and destroy infected body cells. Suppressor T cells coordinate the activities of other T cells. They “turn off” or suppress helper T cells when the infection has been cleared. Lymphocytes called B cells produce antibodies. Each B cell is programmed to make one type of antibody, specific to a particular pathogen. An antibody is a protein that acts against a specific antigen. Specific Defenses

33. Lesson 2 Active and Passive Immunity Active Immunity The immunity your body develops to protect you from measles and from other diseases is called active immunity. Naturally acquired active immunity develops when your body is exposed to antigens from invading pathogens. Artificially acquired active immunity develops in response to a vaccine. Passive Immunity A vaccine is a preparation of dead or weakened pathogens, which are introduced into the body to stimulate an immune response. The Role of Memory Lymphocytes

34. Lesson 2 A. Correct! Physical and chemical barriers that pathogens encounter when they try to enter the human body do NOT include the following: cortisone. Quick Review - Answer

35. Lesson 2 You have answered the question incorrectly. Go back to try again, or click Next to view the correct answer. Quick Review - Answer

36. Lesson 2 A. Correct! The immunity your body develops to protect you from measles and other diseases is called active immunity. You also can be protected from pathogens by passive immunity—receiving antibodies from another person or an animal. Quick Review - Answer

37. Lesson 2 You have answered the question incorrectly. Go back to try again, or click Next to view the correct answer. Quick Review - Answer

38. Lesson 2 A. Correct! Your family physician and your local health department are available to advise you on the immunizations you need. Quick Review - Answer

39. Lesson 2 You have answered the question incorrectly. Go back to try again, or click Next to view the correct answer. Quick Review - Answer

40. Lesson 2 A. Correct! Vaccines have influenced the health status of individuals, families, communities, and the whole world. Quick Review - Answer