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Urinary system: imaging diagnosis

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1 Urinary system: imaging diagnosis
唐光健

2 Questions to think of Which diagnostic imaging modality is the most suitable for the urinary system and why? What urinary diseases are suitable for imaging examination? What imaging method should be chosen with different sort of disease considered clinically? What information we expect to get from the imaging?

3 Urinary System Characteristics: poor natural contrast
Luminal Structure calyces, pelvic, ureter, bladder -UROGRAPHY Parenchyma Kidney-cortex, medulla -TOMOGRAPHIC IMAGING

4 Imaging modalities: plane film(KUB)-limited effective Urography
Intravenous pyelography IVP Retrograde pyelography Cystography Urethrography show morphous of the lumen indirectly -overall view of the urinary tract -affected by the renal function & lumen construction Ultrasonography USG real time, convenient, low cost, available -good characteristic of stone, fluid CT Computed Tomography high resolution of high density & low density -contrast enhancement MRI Magnetic Resonant Imaging -good contrast of soft tissues

5 Normal Manifestations
KUB: contour of kidney -edge, density, size, position…

6 Normal Manifestations
IVP –compress the ureter, picture 15’-30’ after contrast administration renal papilla Vtx body formix major calyx-neck minor calyx fundament renal pelvic ureter bladder

7 Normal Manifestations
IVP –compress the ureter, picture 15’-30’ after contrast administration renal papilla Vtx body formix major calyx-neck minor calyx fundament renal pelvic ureter

8 Normal Manifestations
IVP-normal variant branching ampullary

9 Normal Manifestations
retrograde pyelogram back flow-collecting duct BF, renal sinus BF, perivein BF, lymph duct BF

10 Normal Manifestations
B-mode sonography- renal sinus, renal parenchyma, renal profile…

11 Normal Manifestations
CT– without/with contrast ~cortical phase, parenchymal phase, excrete phase ~profile, density, enhancement… Parenchymal phase cortical phase plane scan

12 Normal Manifestations
CT– without/with contrast ~cortical phase, parenchymal phase, excrete phase ~profile, density, enhancement… Parenchymal phase excretive phase cortical phase

13 Normal Manifestations
Angiography– ~no routine method, with interventional therapy ~arterial ph. parenchymal ph. Veinal ph.

14 Normal Manifestations
MRI- T1WI higher SI with cortex T2WI homogeneous high SI (signal intensity) T2WI T1WI

15 Renal pathologies pathologies of Parenchymal
Solid -benign: angiomyolipoma -malignant: carcinoma Cystic inside kidney: renal cyst      outside kidney: sub capsule hematoma pathologies of Urinary tract of the wall –transitional cell carcinoma of the lumen –calculus Inflammatory change-tuberculosis Hydronephrosis –differentiate diagnosis

16 Renal pathologies pathologies of Parenchymal
Solid -benign: angiomyolipoma -malignant: carninoma Cystic inside kidney: renal cyst      outside kidney: sub capsule hematoma pathologies of Urinary tract of the wall –transitional cell carcinoma of the lumen –calculus Inflammatory change-tuberculosis Hydronephrosis –differentiate diagnosis

17 Renal solid malignant renal carcinoma neoplasm, vascularity, necrosis

18 Renal solid malignant pathologic features correlate to imaging
neoplasm-mass effect neoplastic vascularity necrosis & bleeding in side the mass

19 Renal solid malignant renal carcinoma neoplasm, vascularity, common with necrosis plain film: profile change-helpless with diag. urography: elongated & deformed pelvic- poor specification BUS: substantial, hypo/inhomogeneous echoic angiography: vessel shift, tumor flashing, neo-vessel Staging CT high specific & sensitive Staging MRI Seldom used

20 Renal solid malignant renal carcinoma
plain film: profile change-helpless with diag.

21 Renal solid malignant renal carcinoma
urography: elongated & deformated pelvic-poor specification

22 Renal solid malignant renal carcinoma
BUS: substantial, hypo/inhomog eneous echoic

23 Renal solid malignant renal carcinoma
CT high specific & sensitive Staging plain scan delay scan With enhancemnet

24 Renal solid malignant renal carcinoma
CT high specific & sensitive Staging delay scan plain scan with enhancement

25 Renal solid malignant renal carcinoma
angiography: vessel shift, tumor flashing, neo-vessel. Staging parenchymal phase post ia adrenalin arterial phase

26 Renal solid malignant renal carcinoma
CT high specific & sensitive Staging renal vein, IVC invaded by RCC

27 Renal solid malignant renal carcinoma
CT high specific & sensitive Staging renal vein, IVC invaded by RCC

28 Renal solid malignant renal carcinoma
angiography: vessel shift, tumor flashing, neo-vessel. Staging Arterial phase Parenchymal phase

29 Renal s solid malignant
renal carcinoma angiography: vessel shift, tumor flashing, neo-vessel. Staging post embolizing of RA IVC angiography

30 Renal solid malignant renal carcinoma MRI seldom use

31 Renal solid benign Renal hamartoma (angiomyolipoma) - ratio of tree elements various, bleeding often

32 Renal solid malignant Angiomyolipoma
pathologic features correlate to imaging neoplasm-mass effect adipose tissue, smooth muscle, vessels hypo-developed neoplastic vessels-bleeding

33 Renal solid benign renal angiomyolipoma
plain film: profile change-helpless with diag. urography: elongated & deformed pelvic-poor specification sonography: hyperechoic substantial mass mostly CT: high specific with fat density, high sensitive, bleeding might be seen MRI inhomogeneous signal, signal of fat & old bleeding

34 Renal solid benign renal angiomyolipoma
sonography: hyperechoic substantial mass mostly

35 Renal solid benign renal angiomyolipoma
CT high specific with fat density, high sensitive, bleeding might be seen CT plain scan with enhancement

36 Renal solid benign renal angiomyolipoma
CT high specific with fat density, high sensitive, bleeding might be seen with enhancement CT plain scan

37 Renal solid benign renal angiomyolipoma
CT high specific with fat density, high sensitive, bleeding might be seen with enhancement Coronal MPR

38 Renal pathologies pathologies of Parenchymal
Solid -benign: angiomyolipoma -malignant: carninoma Cystic inside kidney: renal cyst      outside kidney: sub capsule hematoma pathologies of Urinary tract of the wall –transitional cell carcinoma of the lumen –calculus Inflammatory change-tuberculosis Hydronephrosis –differentiate diagnosis

39 Renal pathologies pathologies of Parenchymal
Solid -benign: angiomyolipoma -malignant: carninoma Cystic inside kidney: renal cyst      outside kidney: sub capsule hematoma pathologies of Urinary tract of the wall –transitional cell carcinoma of the lumen –calculus Inflammatory change-tuberculosis Hydronephrosis –differentiate diagnosis

40 cystic, inside kidney-renal cyst
pathologic features correlate to imaging with thin, even wall, flat epithelium clear fluid inside & no blood flow

41 cystic, inside kidney-renal cyst
plain film: profile changing urography: pelvix & calix deforming, no specific BUS: anechoic lesion, high specific CT: clear appearance, high sen. & spe. for calcification of the wall or septation MRI:cystic, signal of fluids, different diagnosis needed if signal be non-specific

42 cystic, inside kidney-renal cyst
Urography deforming of pelvic & calculi, low specific

43 cystic, inside kidney-renal cyst C
BUS, high specific anechoic lesion, echo enhancement post.

44 cystic, inside kidney-renal cyst C
CT: clear appearance, high sen. & spe. for calcification of the wall or septation Waterlike, no enhancement, “no wall”

45 cystic, inside kidney-renal cyst C
CT: clear appearance, high sen. & spe. for calcification of the wall or septation

46 cystic, inside kidney-renal cyst C
CT: clear appearance, high sen. & spe. for calcification, differentiation with high density cyst Enhancement scan Plain scan

47 cystic, inside kidney-renal cyst C
MRI, atypical signal-differentiate cystic, sig. of fluid

48 cystic, inside kidney-renal cyst
Multicystic kidney

49 cystic, inside kidney-multycystic kidney
plain film: enlargement & shift of renal shadow urography: elongation/deformation of the pelvic BUS: renal enlargement of both sides with multi-cyst ~ diagnosed CT: manifest clear, with multi-cystic liver often

50 cystic, inside kidney-multycystic kidney
plain film: enlargement & shift of renal shadow urography: elongation/deformation of the pelvic BUS: renal enlargement of both sides with multi-cyst ~ diagnosed CT: manifest clear, with multi-cystic liver often

51 cystic, inside kidney-multycystic kidney
urography: elongation/ deformation of the pelvic

52 cystic, inside kidney-multycystic kidney
BUS: renal enlargement of both sides with multi-cyst ~ diagnosed

53 cystic, inside kidney-multycystic kidney
CT: manifest clear, with multi-cystic liver often

54 Renal pathologies pathologies of Parenchymal
Solid -benign: angiomyolipoma -malignant: carninoma Cystic inside kidney: renal cyst      outside kidney: sub capsule hematoma pathologies of Urinary tract of the wall –transitional cell carcinoma of the lumen –calculus Inflammatory change-tuberculosis Hydronephrosis –differentiate diagnosis

55 Renal pathologies pathologies of Parenchymal
Solid -benign: angiomyolipoma -malignant: carninoma Cystic inside kidney: renal cyst      outside kidney: sub capsule hematoma pathologies of Urinary tract of the wall –transitional cell carcinoma of the lumen –calculus Inflammatory change-tuberculosis Hydronephrosis –differentiate diagnosis

56 cystic, outside-sub capsule hematoma
Imaging character: out of kidney, no blood perfusion, fluid inside, partial solid if clot inside KUB: useless BUS: crescent anechoic area outside kidney adjacent kidney deform echoic if clot in hematoma

57 cystic, outside-sub capsule hematoma
CT: crescent, low density, high density if clot within hematoma, no enhancement, kidney deform

58 cystic, outside-sub capsule hematoma
Angiography: renal vessel compressed & shifted find source of bleeding

59 Renal pathologies pathologies of Parenchymal
Solid -benign: angiomyolipoma -malignant: carninoma Cystic inside kidney: renal cyst      outside kidney: sub capsule hematoma pathologies of Urinary tract of the wall –transitional cell carcinoma of the lumen –calculus Inflammatory change-tuberculosis Hydronephrosis –differentiate diagnosis

60 Renal pathologies pathologies of Parenchymal
Solid -benign: angiomyolipoma -malignant: carninoma Cystic inside kidney: renal cyst      outside kidney: sub capsule hematoma pathologies of Urinary tract of the wall –transitional cell carcinoma of the lumen –calculus Inflammatory change-tuberculosis Hydronephrosis –differentiate diagnosis

61 pathologies of Urinary tract wall
carcinoma of renal pelvis

62 pathologies of Urinary tract wall
carcinoma of renal pelvis neoplasm, often small, seldom necrosis plain film: helpless urography: filling defect, high sensitive sonography: hypoechoic substantial mass in pelvic/ureter CT: slight/medial enhancement, filling defect in hydronephrostic pelvic/ureter in excrete phase Staging MRI equivalent SI in T1 & T2WI

63 pathologies of Urinary tract wall
carcinoma of renal pelvis neoplasm, often small, seldom necrosis plain film: helpless urography: filling defect, high sensitive sonography: hypoechoic substantial mass in pelvic/ureter CT: slight/medial enhancement, filling defect in hydronephrostic pelvic/ureter in excrete phase Staging MRI equivalent SI in T1 & T2WI

64 pathologies of Urinary tract wall
carcinoma of renal pelvis urography: filling defect, high sensitive

65 pathologies of Urinary tract wall
carcinoma of renal pelvis CT: slight/medial enhancement, filling defect in hydronephrostic pelvic/ureter in excrete phase Staging with enhancement plain scan delay scan

66 pathologies of Urinary tract wall
carcinoma of renal pelvis CT: slight/medial enhancement, filling defect in hydronephrostic pelvic/ureter in excrete phase Staging

67 pathologies of Urinary tract wall
carcinoma of renal pelvis MRI equivalent SI in T1 & T2WI T2WI T1WI STAGE

68 pathologies of Urinary tract wall
carcinoma of renal pelvis urography: filling defect, high sensitive

69 pathologies of Urinary tract wall
carcinoma of ureter CT: slight/medial enhancement, filling defect in hydronephrostic pelvic/ureter in excrete phase Staging delay scan with enhancement plain scan

70 pathologies of Urinary tract wall
carcinoma of ureter MRI equivalent SI in T1 & T2WI, hydrography

71 Renal pathologies pathologies of Parenchymal
Solid -benign: angiomyolipoma -malignant: carinoma Cystic inside kidney: renal cyst      outside kidney: sub capsule hematoma pathologies of Urinary tract of the wall –transitional cell carcinoma of the lumen –calculus Inflammatory change-tuberculosis Hydronephrosis –differentiate diagnosis

72 Renal pathologies pathologies of Parenchymal
Solid -benign: angiomyolipoma -malignant: carninoma Cystic inside kidney: renal cyst      outside kidney: sub capsule hematoma pathologies of Urinary tract of the wall –transitional cell carcinoma of the lumen –calculus Inflammatory change-tuberculosis Hydronephrosis –differentiate diagnosis

73 pathologies of Urinary tract lumen- lithiasis
90% X-ray positive, diagnose considering clinical data KUB: renal calculi-pelvic/calix (staghorn stone) ureter calculi-? CT: high sensitive, exact positioning USG: high specific but low sensitive with ureter calculi

74 pathologies of Urinary tract lumen- lithiasis
KUB: renal calculi-pelvic/calix (staghorn stone) ureter calculi-?

75 pathologies of Urinary tract lumen- lithiasis
Sonography: renal calculi-pelvic/calix (staghorn stone) ureter calculi-?

76 pathologies of Urinary tract lumen- lithiasis
CT: high sensitive, exact positioning Enhancement scan slab MIP plane scan

77 pathologies of Urinary tract lumen- lithiasis
KUB: Urography: renal calculi-pelvic/calix ureter calculi-?

78 pathologies of Urinary tract lumen- lithiasis
CT: high sensitive, exact positioning Enhancement scan MIP plane scan

79 pathologies of Urinary tract lumen- lithiasis
MRI: no routine, low SI both T1WI & T2WI

80 pathologies of Urinary tract lumen- lithiasis
CT: high sensitive, exact positioning

81 pathologies of Urinary tract lumen- lithiasis
USG: high specific but low sensitive with ureter calculi

82 pathologies of Urinary tract lumen- lithiasis
CT: high sensitive, exact positioning plane scan Enhancement scan

83 pathologies of Urinary tract lumen- lithiasis
Soft tissue around cal., hydronephrosis proximately

84 pathologies of Urinary tract lumen- lithiasis
Soft tissue around cal., hydronephrosis proximately

85 Renal pathologies pathologies of Parenchymal
Solid -benign: angiomyolipoma -malignant: carinoma Cystic inside kidney: renal cyst      outside kidney: sub capsule hematoma pathologies of Urinary tract of the wall –transitional cell carcinoma of the lumen –calculus Inflammatory change-tuberculosis Hydronephrosis –differentiate diagnosis

86 Renal pathologies pathologies of Parenchymal
Solid -benign: angiomyolipoma -malignant: carninoma Cystic inside kidney: renal cyst      outside kidney: sub capsule hematoma pathologies of Urinary tract of the wall –transitional cell carcinoma of the lumen –calculus Inflammatory change-tuberculosis Hydronephrosis –differentiate diagnosis

87 Inflammatory change-renal tuberculosis
nephropyelitis  renal papilla ulcer  necrosis, cavitation  pyonephrosiscalcification, renal self- resection imaging KUB: (-) /calcification Urography: edge irregular (insect bite), cavitation, pelvic/ureter deform CT: sensitive with cal. but pelvic/ureter deform MRI insensitive diag. – consider clinical data

88 Inflammatory change-renal tuberculosis
imaging KUB (-) / calcification Self-resection

89 Inflammatory change-renal tuberculosis
imaging Urography: edge irregular (insect bite), cavitation, pelvic/ureter deform ulcer of renal papillae cavitation

90 Inflammatory change-renal tuberculosis
imaging CT sensitive with cal. but with pelvic/ureter deform plain CTscan enhancement

91 Inflammatory change-renal tuberculosis
imaging CT sensitive with cal. also with pelvic/ureter deform -MSCT enhancement delayed plain CTscan

92 Inflammatory change-renal tuberculosis
imaging CT sensitive with cal. also with pelvic/ureter deform -MSCT enhancement plain CTscan

93 Inflammatory change-renal tuberculosis
imaging CT sensitive with cal. also with pelvic/ureter deform -MSCT

94 Inflammatory change-renal tuberculosis
imaging CT sensitive with cal. also with pelvic/ureter deform -MSCT

95 Hydronephrosis-summary

96 Hydronephrosis - summary
Obstruction of the urinary tract malformation, calculi, tuberculosis, inflammation, compression from outside-retroperitoneal fibrosis… imaging-various dilatation of pelvis/uriter plain film: renal shadow enlarged, no cause be diagnosis except calculi of urinary tract urography: some causes can be diagnosed sonography: high sensitivity and cause-diagnositic CT: cause-diagnostic, sensitivity relatively high MRI: seldom used, urography partly rapalced by uro- hydrography

97 Hydronephrosis - summary
Obstruction of the urinary tract malformation, calculi, tuberculosis, inflammation, compression from outside-retroperitoneal fibrosis… imaging-various dilatation of pelvis/uriter plain film: renal shadow enlarged, no cause be diagnosis except calculi of urinary tract urography: some causes can be diagnosed sonography: high sensitivity and cause-diagnositic CT: cause-diagnostic, sensitivity relatively high MRI: seldom used, urography partly rapalced by uro- hydrography

98 Hydronephrosis - summary
Obstruction of the urinary tract malformation, calculi, tuberculosis, inflammation, compression from outside-retroperitoneal fibrosis… imaging-various dilatation of pelvis/ureter plain film: renal shadow enlarged, no cause be diagnosis except calculi of urinary tract urography: some causes can be diagnosed sonography: high sensitivity and cause-diagnositic CT: cause-diagnostic, sensitivity relatively high MRI: seldom used, urography partly rapalced by uro- hydrography

99 Hydronephrosis urography (retrograde ) Ureteral carcinoma

100 Hydronephrosis urography: (IVP, retro, percutaneous ) some causes can be diagnosed

101 Hydronephrosis - summary
Obstruction of the urinary tract malformation, calculi, tuberculosis, inflammation, compression from outside-retroperitoneal fibrosis… imaging-various dilatation of pelvis/uriter plain film: renal shadow enlarged, no cause be diagnosis except calculi of urinary tract urography: some causes can be diagnosed sonography: high sensitivity and cause-diagnositic CT: cause-diagnostic, sensitivity relatively high MRI: seldom used, urography partly rapalced by uro- hydrography

102 Hydronephrosis - summary
Obstruction of the urinary tract malformation, calculi, tuberculosis, inflammation, compression from outside-retroperitoneal fibrosis… imaging-various dilatation of pelvis/uriter plain film: renal shadow enlarged, no cause be diagnosis except calculi of urinary tract urography: some causes can be diagnosed sonography: high sensitivity and cause-diagnositic CT: cause-diagnostic, sensitivity relatively high MRI: seldom used, urography partly rapalced by uro- hydrography

103 Hydronephrosis-summary
sonography: high sensitivity and cause-diagnositic

104 Hydronephrosis-summary
sonography: high sensitivity and cause-diagnositic

105 Hydronephrosis - summary
Obstruction of the urinary tract malformation, calculi, tuberculosis, inflammation, compression from outside-retroperitoneal fibrosis… imaging-various dilatation of pelvis/uriter plain film: renal shadow enlarged, no cause be diagnosis except calculi of urinary tract urography: some causes can be diagnosed sonography: high sensitivity and cause-diagnositic CT: cause-diagnostic, sensitivity relatively high MRI: seldom used, urography partly rapalced by uro- hydrography

106 Hydronephrosis - summary
Obstruction of the urinary tract malformation, calculi, tuberculosis, inflammation, compression from outside-retroperitoneal fibrosis… imaging-various dilatation of pelvis/uriter plain film: renal shadow enlarged, no cause be diagnosis except calculi of urinary tract urography: some causes can be diagnosed sonography: high sensitivity and cause-diagnositic CT: cause-diagnostic, sensitivity relatively high MRI: seldom used, urography partly replaced by uro- hydrography

107 Hydronephrosis-summary
CT: cause-diagnostic, sensitivity relatively high delay scan plain scan enhanced

108 Hydronephrosis-summary
CT: cause-diagnostic, sensitivity relatively high ureteral carcinoma

109 Hydronephrosis-summary
CT: cause-diagnostic, sensitivity relatively high retroperitoneal fibrosis

110 Hydronephrosis-summary
CT: cause-diagnostic, sensitivity relatively high retroperitoneal fibrosis

111 Hydronephrosis - summary
Obstruction of the urinary tract malformation, calculi, tuberculosis, inflammation, compression from outside-retroperitoneal fibrosis… imaging-various dilatation of pelvis/uriter plain film: renal shadow enlarged, no cause be diagnosis except calculi of urinary tract urography: some causes can be diagnosed sonography: high sensitivity and cause-diagnositic CT: cause-diagnostic, sensitivity relatively high MRI: seldom used, urography partly rapalced by uro- hydrography

112 Hydronephrosis - summary
Obstruction of the urinary tract malformation, calculi, tuberculosis, inflammation, compression from outside-retroperitoneal fibrosis… imaging-various dilatation of pelvis/uriter plain film: renal shadow enlarged, no cause be diagnosis except calculi of urinary tract urography: some causes can be diagnosed sonography: high sensitivity and cause-diagnositic CT: cause-diagnostic, sensitivity relatively high MRI: seldom used, urography partly rapalced by uro- hydrography

113 Hydronephrosis-summary
MRI: seldom used, urography partly rapalced by uro-hydrography retroperitoneal fibrosis

114 Prostate: imaging diagnosis

115 Prostate-imaging anatomy
Characteristics: soft-tissue, poor natural X-ray contrast central zone-rich in muscle fiber periphery zone-rich in loose CT & glands

116 Prostate-imaging anatomy
MRI-USG-CT,not shown with plain film

117 Prostate-imaging anatomy
MRI-USG-CT,not shown with plain film T1WI T2WI

118 Prostate-imaging anatomy
MRI-USG-CT,not shown with plain film

119 Prostate-imaging anatomy
MRI-USG-CT,not shown with plain film

120 prostate BHP benign hypertrophy of prostate
sup. border 10mm over the pubis / diameter > 5cm no abnormal signal/echo/density inside

121 prostate BHP MPR with enhancement plain CT scan

122 prostate BHP T2WI T1WI

123 prostate prostate carcinoma
low signal lesion in periphery zone in T2WI staging

124 prostate prostate carcinoma stage C stage B

125 prostate prostate carcinoma with enhancement plain CT scan

126 prostate prostate carcinoma plain CT scan MPR with enhancement

127 Questions after lecture
How to chose imaging exam for the patient with gross hematuria (how to determine the method and purpose of next exam according to the result of pre-exam)? What is the pathologic underlying of the various manifestations of renal carcinoma with different imaging method? What imaging method is the first chosen for the prostate exam?


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