2. Age Management

3. Relative Impact of Curing Diseases and Slowing Aging

4. Calorie Restriction and Life Extension

5. CR Longevity Biomarkers Decreased insulin level. Improved insulin sensitivity. Reduced body fat. Reduced blood pressure. Reduction of hardening of arteries. Less clogging of arteries. Decreased inflammation. Reduction in body temperature. Reduced energy production.

6. Fat Cells

7. Calorie Restriction the proof is present The only proven way documented by science to slow the aging process and increase the health-span in mammals and primates. The genes involved, documented by gene chip analysis can be grouped into 5 main categories: 1. Insulin sensitivity & Blood sugar control 2. Inflammation 3. Anti-oxidant production 4. DNA Repair 5. Gene Expression

8. Our genes, and the environment in which they exist, dictate our health and longevity. Positive Environment + Optimal Gene Function = Improved Aging plus Optimal Health and Quality of Life

9. Genes +Environment = Longevity GENES 25% ENVIRONMENT LIFESTYLE STRESS 75%

11. Human Cell

12. Chromosomes

13. DNA

14. DNA Nucleotides

15. SNP

16. Types Of Mutations

17. Genes

18. Genes & Protein Production

19. I AM HEALTHY I AM HEALTTY I AM HEELTTY Effects of DNA Damage

20. Changing Gene Expression During Aging Positive Aging Active Genes Inactive Genes Inactive Fetal Genes Childhood Profile ASAAAA Developmental Status +S Developmental Status OPTIMAL DNA REPAIR

21. Active Genes Inactive Genes After Age 30 Adult Profile SSAASA Stable Health +S Stable Health DNA DAMAGE ACCELERATES FASTER THAN DNA REPAIR Damage Changing Gene Expression During Aging

22. Active Genes Inactive Genes Active Oncogene Old Age Old Age Profile SSSSA +S Cancer+Disease RAPID ACCELERATION OF DNA DAMAGE AND DECREASING REPAIR CAPACITY Damage Changing Gene Expression During Aging

23. Why Do We Age? Aging is the result of genetic inheritance and the body reproducing DNA that has been damaged by environmental pollution, harmful lifestyle choices and the overall stress of life in the 21 st century.

24. What is Age Management? Age Management is the science of utilizing the genes we have inherited at their most optimal potential, in order to improve our health and quality of life. It is Biological Age, not Chronological Age, that determines the rate of deterioration of the body and its ability to maintain and repair itself.

25. Age Management Therapy Goals 1) Improve Environmental Effects Environment defined as diet, exercise, mind state, toxic elements, pollution, local radiation. 2) Improve the Function of the Aging Equation Control Glycation, Inflammation, Oxidation/Free Radical Levels and Methylation at the cellular level. 3) Improve DNA Replication and Gene Expression –Improve the ratio of DNA repair over DNA damage therefore resulting in less cell mutations and more accurate cell copies during cell replication. This preserves adult stem cell pools. 4) Utilize Personally Directed Genetic Nutrients Optimize genetic expression and health-span.

26. 1.Reduce stress 2.Nourish the genes 3.Exercise the genes 4.Supplement the genes 5.Optimize skin renewal 5 Steps to Looking and Feeling Younger

27. Age Management Food Pyramid

28. Aerobic Exercise

29. Resistive Exercise

32. Personalized Genetic Health & Age Management starts with a Personal Genetic Profile 1. A cheek swab SNPs test to identify genetic weakness How we go from a cheek sample to your genetic profile:

33. Personalized Genetic Health & Age Management starts with a Personal DNA Analysis. 2.A home-based urine test to measure DNA damage and free radical level at the start of the program and to monitor ongoing progress 3. A scientific analysis to develop a personalized program to optimize inherited genetic function for optimal health

34. CORE THERAPEUTIC APPROACH FOR AGE MANAGEMENT PROGRAMS URINE SAMPLE 8 Hydroxy Guanosine = DNA Damage 8 EpiPGF-2alpha = Oxidative Stress

35. Personal DNA Analysis Heart and Vascular Health (Methylation Management) Bone and Joint Health (Inflammation Management) Blood Sugar and Body Fat Control (Glycation Management) Detoxification and Free Radical Control (Oxidation Management) Optimal Cell Function Formula (DNA Repair)