1. STARLIMS Goes Live in 2009! Stuart Bayliss Regional Molecular Genetics Service St Mary’s Hospital, Manchester on behalf of the STARLIMS NHS Genetics Project Consortium

2. Summary Why Our development pathway Current status What the future holds Strategic issues

3. Why 2003: UK Government White Paper: “Our Inheritance, Our Future” 2004: NGRL Manchester Survey of Molecular, Cytogenetic and Clinical Services RMGS deemed systems inadequate for future use 2005: NHS Genetic Service Information Output Based Specification (NGRL, Manchester)

4. Our Development Pathway March 2006 –Evaluation by group of RMGS placed STARLIMS number 1 contender for functionality and value June 2006 - December 2007 –7 RMGS laboratories involved STARLIMS development on a consortium basis holding monthly meetings –Employ UKGTN adopted data dictionary –Agree shared development of functional toolkit which now defines the ‘core’ genetics module within STARLIMS –Non stringent project management December 2007 –Establish Project Steering Group –Prioritise local implementation order

5. Our Development Pathway January 2008 –Rolling localisation efforts mapped out –Site specific work began in Salisbury and Oxford Labs –Target ‘go live’ date of 1 st April 2008… … January 2009 –Oxford lab goes live! Development Complexity The development cycle Resource requirements (Lab & STARLIMS UK)

6. The Development Cycle Lab Testing STARLIMS Development Issues reporting Requirements gathering

7. Current Status Oxford lab live Salisbury lab –parallel running, go live 30 th March 2009 Sheffield lab –intense localisation development –2 week lab prioritisation in order to facilitate go-live –expected go-live in mid-April Exeter and Nottingham labs –undergoing local gap analysis work –begin localisation work with STARLIMS once Sheffield completes Birmingham and Manchester –due gap analysis over summer, localisation work in Autumn –expected go live dates October to December 2009

8. Current Status/What the future holds ‘ Core’ deliverables –Sample lifecycle (booking-in to reporting) –Diseases and Tests –Sample workflows –Test parameters and sample information are used to drive processes –Dynamic and Template based plate mapping –Triggers –Instrument and Software Integration Shift away from disease specialisation to process specialisation where required Improved laboratory performance and patient experience

9. What the future holds Standardisation Integrated instruments & software Better audit data Enriched management information Cytogenetics development (Clinical development) Continued iterative development (local vs core) Better project management Communications –Lab to lab –UKGTN catalogue –Clinical coding: ICD10 revision – Rare Disease Taskforce, WHO, SNOMED CT via NGRL(M)

10. Strategic Issues Project approach Requirements, Requirements, Requirements! Project creep People, time and money Be realistic Engage

11. Acknowledgements Colleagues in the consortium (development and steering) Rick Jones, Yorkshire Centre for Health Informatics, SG Chair Exeter RMGS Manchester RMGS Nottingham RMGS Oxford RMGS Salisbury RMGS Sheffield RMGS West Midlands RMGS STARLIMS (UK & US Offices) NGRL, Manchester