1. Biotechnology in North Carolina

2. Biotechnology in N.C. What is biotechnology ? A collection of technologies that use living cells and/or biological molecules to solve problems and make useful products.

3. Biotechnology in N.C.  The making of these products is called biomanufacturing or bioprocessing.

4. Biotechnology in N.C.  More than 600+ biotechnology companies  Companies involved in industries such as aquaculture, biodefense, medical devices, nutrition, pharmaceutical development and manufacturing, diagnostics and medical devices  Together, they employ more than 60,000 people. Taken from http://ncbioscience.net/about-us/MemberList.aspx.http://ncbioscience.net/about-us/MemberList.aspx

5. Biotechnology in N.C. Types of products made in N.C. include:  Vaccines for humans and animals  Biopharmaceuticals  Amino acids  Industrial enzymes  Therapeutics isolated from blood  Diagnostic kits  Biofuels

6. Biogen Idec Produces biopharmaceuticals to treat neurodegenerative diseases, hemophilia, and autoimmune disorders. Its large-scale manufacturing in Research Triangle Park is one of the largest Biologics manufacturing facilities of its kind in the world.

7. Ajinomoto Is a world leader in the production of amino acids, the building blocks of proteins. Like many bioprocessing facilities, the Raleigh plant operates at full capacity 24 hours a day, 365 days a year.

8. Is a world leader in production of recombinant protein biopharmaceuticals. Its state-of-the- art facilities are located in Research Triangle Park. Fujifilm Diosynth Biotechnologies

9. AlphaVax Is developing a new vaccine technology with broad applications against infectious disease, cancer and biodefense threats.

10. Novozymes North America Is located on 1,600 acres in Franklinton. It is the largest multi- purpose enzyme manufacturing plant in the United States. Novozymes is the biotech-based world leader in industrial enzymes and microorganisms.

11. Greer Labs Is a leading supplier of allergy testing and treatment materials. Its manufacturing facility is located in Lenoir.

12. KBI BioPharma Is a contract biomanufacturer in Durham. The company produces a variety of biopharmaceuticals for other companies.

13. Argos Therapeutics Is developing personalized immunotherapies for the treatment of cancer and infectious diseases in Durham.

14. Takes plasma and develops life saving therapies for immune deficiencies, hemophilia and other blood disorders. Talecris Plasma Resources

15. Archer Daniels Midland Is one of the largest agricultural processors in the world. The plant, in Southport, N.C., produces citric acid.

16. Ingredion Produces high-fructose corn syrup and starch in Winston- Salem.

17. Merck & Co. The Durham facility manufactures bulk varicella for use in vaccines for chicken pox and shingles.

18. GlaxoSmithKline The Research Triangle Park campus is one of the two administrative headquarters in the U.S. It houses research and development facilities, sales and marketing.

19. BASF Plant Science BASF at Research Triangle Park focuses on insecticide and serves as the headquarters for the BASF Crop Protection NAFTA division.

20. Pfizer Pfizer Global Supply site is located in Sanford, North Carolina. The site produces vaccines for consumers around the world.

21. Novartis Novartis has a facility located in Holly Spring which has a 430,000- square-foot facility for producing flu vaccine using cell culture techniques.

22. Liquidia Liquidia uses PRINT technology to manufacture specifically engineered particles.