1. The Cell Cycle 5A How eukaryotic cells divide to make new cells

2. Just like people have phases of development,

3. Cells have phases too.

4. In somatic (body) cells, a parent cell produces 2 daughter cells. The purpose of mitosis is for growth and repair of tissue.

5. Three Phases or Stages 1. Interphase 2. M (Mitosis) phase 3.Cytokinesis

6. Interphase

7. DNA and organelles replicate Cell spends most of its life in this stage

9. Stages of Interphase G1 (growth) S (synthesis) G2 (growth)

10. G1 (growth) Aka First Gap The cell grow larger Makes proteins and organelles

11. S (synthesis) DNA replication occurs - genetic material is duplicated so each daughter cell contains the same amount of genetic material as the parent cell Chromosomes duplicate to form sister chromatids

14. G2 (growth) Aka Second Gap More growth & protein synthesis occurs preparing for cell division

16. M phase Aka Mitosis Shortest of all phases Division of the nucleus

17. Mitosis Nucleus divides Duplicated DNA is divided into two new nuclei

19. Mitosis Animation

20. Stages of Mitosis Prophase Metaphase Anaphase Telophase

21. Prophase

22. Nuclear membrane breaks down Genetic material (chromosomes) enlarges, thickens &condenses In the cytoplasm, Centrioles migrate to opposite ends of poles Microtubules attach to centrioles

23. Prophase

24. Metaphase

25. Duplicated chromosomes line up on the equator of the cell Spindles attach to chromosomes at the centromere & pull the sister chromatids into a line in the center of the cell

26. Metaphase

27. Anaphase

28. Shortest phase As the spindle contracts, the sister chromatids separate and are pulled to opposite sides of the cell

29. Anaphase

30. Telophase

31. New nuclear membranes form to separate the genetic material Chromosomes shrink Spindle breaks apart

32. Telophase

33. Mitosis

34. Cytokinesis

35. Occurs AFTER telophase and BEFORE interphase Cytoplasm divides Forms 2 new cells

36. Cytokinesis

39. http://outreach.mcb.harvard.edu/animations/ cellcycle.swf

41. Identify the stage of the cell cycle…

45. http://bio.rutgers.edu/~gb101/lab2_mitosis/in dex2.html

46. What happens when cells divide at an uncontrollable rate? CANCER 5D

48. Cancer Animation

52. Cancer is caused by the loss of cell’s ability to control division. Cancer cells divide uncontrollably.

53. Causes of Cancer Tobacco Radiation exposure Viral infections (HPV) Genetics

54. http://www.mhhe.com/biosci/genbio/virtual_l abs/BL_23/BL_23.html