Presentation is loading. Please wait.

Presentation is loading. Please wait.

Implementation and use of whole exome sequencing for metastatic solid cancer  Manon Réda, Corentin Richard, Aurelie Bertaut, Julie Niogret, Thomas Collot,

Published byNoreen Richards Modified over 5 years ago

Similar presentations

Presentation on theme: "Implementation and use of whole exome sequencing for metastatic solid cancer  Manon Réda, Corentin Richard, Aurelie Bertaut, Julie Niogret, Thomas Collot,"— Presentation transcript:

1 Implementation and use of whole exome sequencing for metastatic solid cancer 
Manon Réda, Corentin Richard, Aurelie Bertaut, Julie Niogret, Thomas Collot, Jean David Fumet, Julie Blanc, Caroline Truntzer, Isabelle Desmoulins, Sylvain Ladoire, Audrey Hennequin, Laure Favier, Leila Bengrine, Julie Vincent, Alice Hervieu, Jean-Florian Guion Dusserre, Come Lepage, Pascal Foucher, Christophe Borg, Juliette Albuisson, Laurent Arnould, Sophie Nambot, Laurence Faivre, Romain Boidot, Francois Ghiringhelli  EBioMedicine  Volume 51, (January 2020) DOI: /j.ebiom Copyright © 2019 The Authors Terms and Conditions

2 Fig. 1 a. Flow chart. b. Main tumor types in the trial.
EBioMedicine  , DOI: ( /j.ebiom ) Copyright © 2019 The Authors Terms and Conditions

3 Fig. 2 Genomic characteristics. a. List of top mutated genes. b. top mutated genes in main cancers. c. Tumor mutational burden value across tumor type. d. relation between Tumor mutational burden and alterations in DNA repair pathways. e. List of constitutional alterations in actionable genes. (d,e: Lines represent median and interquartile ranges); for panel d * mean p value< 0.05 (Mann-Whitney test). EBioMedicine  , DOI: ( /j.ebiom ) Copyright © 2019 The Authors Terms and Conditions

Download ppt "Implementation and use of whole exome sequencing for metastatic solid cancer  Manon Réda, Corentin Richard, Aurelie Bertaut, Julie Niogret, Thomas Collot,"

Similar presentations

Waging War on Cancer with the Sword of Immunity Cell Volume 158, Issue 2, (July 2014) DOI: 10.1016/j.cell.2014.07.006 Copyright © 2014 Terms and Conditions.

Waging War on Cancer with the Sword of Immunity Cell Volume 158, Issue 2, (July 2014) DOI: /j.cell Copyright © 2014 Terms and Conditions.
2015 Alzheimer's disease facts and figures Alzheimer's & Dementia: The Journal of the Alzheimer's Association Volume 11, Issue 3, Pages 332-384 (March.

2015 Alzheimer's disease facts and figures Alzheimer's & Dementia: The Journal of the Alzheimer's Association Volume 11, Issue 3, Pages (March.
Volume 12, Pages (October 2016)

Volume 12, Pages (October 2016)
Multiplex Ultrasensitive Genotyping of Patients with Non-Small Cell Lung Cancer for Epidermal Growth Factor Receptor (EGFR) Mutations by Means of Picodroplet.

Multiplex Ultrasensitive Genotyping of Patients with Non-Small Cell Lung Cancer for Epidermal Growth Factor Receptor (EGFR) Mutations by Means of Picodroplet.
PIKHER2: A phase IB study evaluating buparlisib in combination with lapatinib in trastuzumab-resistant HER2-positive advanced breast cancer  Mathilde.

PIKHER2: A phase IB study evaluating buparlisib in combination with lapatinib in trastuzumab-resistant HER2-positive advanced breast cancer  Mathilde.
Volume 15, Issue 3, Pages (March 2014)

Volume 15, Issue 3, Pages (March 2014)
Gemcitabine plus cisplatin versus chemoradiotherapy in locally advanced biliary tract cancer: Fédération Francophone de Cancérologie Digestive 9902 phase.

Gemcitabine plus cisplatin versus chemoradiotherapy in locally advanced biliary tract cancer: Fédération Francophone de Cancérologie Digestive 9902 phase.
Combined Mass Spectrometry Imaging and Top-down Microproteomics Reveals Evidence of a Hidden Proteome in Ovarian Cancer  Vivian Delcourt, Julien Franck,

Combined Mass Spectrometry Imaging and Top-down Microproteomics Reveals Evidence of a Hidden Proteome in Ovarian Cancer  Vivian Delcourt, Julien Franck,
Volume 2, Issue 8, Pages (August 2015)

Volume 2, Issue 8, Pages (August 2015)
Volume 2, Issue 12, Pages (December 2015)

Volume 2, Issue 12, Pages (December 2015)
Alcohol Consumption as a Risk Factor for Acute and Chronic Pancreatitis: A Systematic Review and a Series of Meta-analyses  Andriy V. Samokhvalov, Jürgen.

Alcohol Consumption as a Risk Factor for Acute and Chronic Pancreatitis: A Systematic Review and a Series of Meta-analyses  Andriy V. Samokhvalov, Jürgen.
Juan W. Valle, Sandrine Faivre, Richard A

Juan W. Valle, Sandrine Faivre, Richard A
Volume 3, Pages (January 2016)

Volume 3, Pages (January 2016)
High-Throughput Gene Expression and Mutation Profiling: Current Methods and Future Perspectives Breast Care 2013;8:401-406 - DOI:10.1159/000357461 Fig.

High-Throughput Gene Expression and Mutation Profiling: Current Methods and Future Perspectives Breast Care 2013;8: DOI: / Fig.
Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: A systematic review  Christian Thoma, Christopher P. Day, Michael.

Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: A systematic review  Christian Thoma, Christopher P. Day, Michael.
Whole Exome Sequencing Reveals Severe Thrombophilia in Acute Unprovoked Idiopathic Fatal Pulmonary Embolism  Matt Halvorsen, Ying Lin, Barbara A. Sampson,

Whole Exome Sequencing Reveals Severe Thrombophilia in Acute Unprovoked Idiopathic Fatal Pulmonary Embolism  Matt Halvorsen, Ying Lin, Barbara A. Sampson,
Volume 45, Pages (January 2018)

Volume 45, Pages (January 2018)
New Views into the Prostate Cancer Genome

New Views into the Prostate Cancer Genome
Volume 152, Issue 5, Pages (April 2017)

Volume 152, Issue 5, Pages (April 2017)
Assessing Copy Number Alterations in Targeted, Amplicon-Based Next-Generation Sequencing Data  Catherine Grasso, Timothy Butler, Katherine Rhodes, Michael.

Assessing Copy Number Alterations in Targeted, Amplicon-Based Next-Generation Sequencing Data  Catherine Grasso, Timothy Butler, Katherine Rhodes, Michael.

Similar presentations

Ads by Google