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Published byNoreen Richards Modified over 5 years ago
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Implementation and use of whole exome sequencing for metastatic solid cancer
Manon Réda, Corentin Richard, Aurelie Bertaut, Julie Niogret, Thomas Collot, Jean David Fumet, Julie Blanc, Caroline Truntzer, Isabelle Desmoulins, Sylvain Ladoire, Audrey Hennequin, Laure Favier, Leila Bengrine, Julie Vincent, Alice Hervieu, Jean-Florian Guion Dusserre, Come Lepage, Pascal Foucher, Christophe Borg, Juliette Albuisson, Laurent Arnould, Sophie Nambot, Laurence Faivre, Romain Boidot, Francois Ghiringhelli EBioMedicine Volume 51, (January 2020) DOI: /j.ebiom Copyright © 2019 The Authors Terms and Conditions
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Fig. 1 a. Flow chart. b. Main tumor types in the trial.
EBioMedicine , DOI: ( /j.ebiom ) Copyright © 2019 The Authors Terms and Conditions
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Fig. 2 Genomic characteristics. a. List of top mutated genes. b. top mutated genes in main cancers. c. Tumor mutational burden value across tumor type. d. relation between Tumor mutational burden and alterations in DNA repair pathways. e. List of constitutional alterations in actionable genes. (d,e: Lines represent median and interquartile ranges); for panel d * mean p value< 0.05 (Mann-Whitney test). EBioMedicine , DOI: ( /j.ebiom ) Copyright © 2019 The Authors Terms and Conditions
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