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Updates in Triple-Negative Breast Cancer
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Introduction to TNBC
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Effects of BRCA Mutations and PARP Inhibitors on DNA Repair Mechanisms in TNBC
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Effects of BRCA Mutations and PARP Inhibitors on DNA Repair Mechanisms in TNBC (cont)
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OlympiAD Olaparib in Patients With mBC and Germline BRCA Mutations
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OlympiAD Olaparib in Patients With mBC and Germline BRCA Mutations (cont)
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EMBRACA Talazoparib in Patients With mBC and Germline BRCA Mutations
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EMBRACA Talazoparib in Patients With mBC and Germline BRCA Mutations (cont)
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PARP Inhibitor AEs
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Drug-Drug Interactions With PARP Inhibitors
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Guidelines for Testing in TNBC
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IMpassion130 First Phase 3 Trial to Show Benefit With IO in TNBC
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Overview of irAEs
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Single-Agent Chemotherapy for PD-L1-Negative, BRCA-WT mTNBC[a]
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Sacituzumab Govitecan Breakthrough Therapy in Heavily Treated Patients
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Current Standard of Care for Locally Advanced TNBC
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Platinum Agents in Neoadjuvant TNBC Therapy Yes or No?
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Platinum Agents in Neoadjuvant TNBC Therapy Yes or No? (cont)
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GeparOLA PARP Inhibition in TNBC Neoadjuvant Therapy
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Emerging Anti-PD-1 Therapy in Neoadjuvant Treatment
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KEYNOTE-522 Confirming Benefit of Pembrolizumab-Containing Neoadjuvant Therapy
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KEYNOTE-522 Study Pathological Complete Response
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Clinical Pearls for Practice
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Abbreviations
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Abbreviations (cont)
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Abbreviations (cont)
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