1. NRP2 expression is associated with prostate cancer progression.
NRP2 expression is associated with prostate cancer progression. A, normal (PNT1A, PZ-HPV7, and RWPE-1) or prostate cancer (LNCaP, C4-2, PC3, and PC3-M) cell lines were immunoblotted (IB) using antibodies to NRP2 or actin. B, expression of NRP2 mRNA was quantified by quantitative PCR (qPCR) in microdissected sections from normal glands, PIN, grade 3 and 5 prostate cancer specimens. C, specimens of normal prostate gland, Gleason grade 3 and 5 carcinoma, and lymph node metastases were immunostained with an NRP2 antibody or a control immunoglobulin G (IgG).
Hira Lal Goel et al. Cancer Discovery 2012;2:
©2012 by American Association for Cancer Research