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THE HUMAN GENOME PROJECT. Gene Myers Let’s sequence the human genome with the shotgun strategy That is impossible, and a bad idea anyway Phil Green 1997.

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Presentation on theme: "THE HUMAN GENOME PROJECT. Gene Myers Let’s sequence the human genome with the shotgun strategy That is impossible, and a bad idea anyway Phil Green 1997."— Presentation transcript:

1 THE HUMAN GENOME PROJECT

2 Gene Myers Let’s sequence the human genome with the shotgun strategy That is impossible, and a bad idea anyway Phil Green 1997 History of Whole Genome Assembly Thanks to Serafim Batzoglou

3 Public Human Genome Project Strategy http://www.genome.gov/ http://www.genome.gov/

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30 Finished Sequence in 2004 (Build 35) http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15496913 http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15496913

31 Finishing Strategy for the Public Genome Project http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed& dopt=Citation&list_uids=15496913

32 Synteny Between Human and Mouse http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citatio n&list_uids=11237011 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citatio n&list_uids=11237011

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