1. Bio 465 Summary

2. Overview Conserved DNA Conserved DNA Drug Targets, TreeSAAP Drug Targets, TreeSAAP Next Generation Sequencing Next Generation Sequencing Assembly Assembly Gene Finding Gene Finding Hidden Markov Models Hidden Markov Models Secondary Structure Secondary Structure Neural Networks Neural Networks Tertiary Structure Tertiary Structure Pymol, Structural Alignment Pymol, Structural Alignment Systems Biology Systems Biology

3. TreeSAAP

4. Conservation

5. Next Generation Sequencing Assembly for de-novo projects Assembly for de-novo projects Expression for human genome Expression for human genome

6. Gene finding

7. Secondary Structure Prediction

8. Neural Networks

9. Tertiary Structure Alignment

10. Systems Biology

11. Pathway Analysis

12. SNPs

13. Goal Improve the human condition Improve the human condition