1. Endoluminal Closure Device
February 6, 2006
Braham Dhillon
Ali Hales
Laura Mattaliano
John Sticklen
John

2. Problem Statement: Close Gastrotomy Incision
John

3. NOTES: Natural Orifice Transluminal Endoscopic Surgery
Using an endoscope, create a gastrotomy to gain access to peritoneal cavity to perform surgery
JPStick

4. Endoscope
Laura

5. Design Parameters Endoscope Incision Port Diameter Length: 110 cm
One Channel: mm
Two Channels: 2.8/3.4mm
Length: 110 cm
Incision
Length: 2 cm
Stomach wall thickness: 3-5 mm
Heal within 7-14 days
Laura

6. Nitinol Mixture of nickel and titanium Thermal Shape Memory
Shape dependent on temperature
Biocompatibility
Several FDA approved devices
High corrosion resistance
Intermetallic, not an alloy
Bonding force between nickel and titanium strong
Elastic Deployment
Pass through narrow canal
Return to original shape
Laura

7. Current Design Ideas: Nitinol Coil
Braham

8. Current Designs Ideas: Suturing Mechanism (based on Bard EndoCinch Suturing System)1 2 3
Braham 4 5

9. Current Design Ideas: “Dhillon’s Grab & Pull”
Braham

10. Heart Patch CardioSEAL® AMPLATZER® Braham
The AMPLATZER® device consists of two wire mesh discs filled with polyester fabric (see photo above). When the device is in proper position, the device is slowly pushed out the catheter until the discs of the device sit on each side of the hole (like a sandwich).
The CardioSEAL® device consists of small double umbrella arms attached to Dacron fabric (see photo above), with special springs. When the device is in proper position, the device is slowly pushed out of the special catheter, the umbrella springs open, and covers each side of the hole (like a sandwich).
CardioSEAL®
AMPLATZER®
pub/guide/tests/procedures/closuredevice.htm

11. Accessories
Braham
Typical accessory device
Forceps pictured here

12. Current Accomplishments
Contacted Dr. Wittig
Access to Nitinol
Determined the final dimensions of endoscope
Scheduled appointment with Dr. Holzman
Patent Search
Hales

13. Current Plan Dr. Holzman Meeting Develop prototype Today, 4pm
Discuss design options and determine final design to work with
Determine Final Budget
Develop prototype
Materials
Exact Dimensions
Hales

14. Future Plans Develop functioning prototype
Ordering Necessary materials
Requesting access to necessary equipment
Determine methods of testing procedure
- Materials with properties of stomach
- Testing on animal stomachs
Hales

15. Questions?

16. References www.gensurg.co.uk ntroi.stanford.edu