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Epidermal thymic stromal lymphopoietin predicts the development of atopic dermatitis during infancy  Jihyun Kim, MD, PhD, Byung Eui Kim, MD, PhD, Jeongok.

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Presentation on theme: "Epidermal thymic stromal lymphopoietin predicts the development of atopic dermatitis during infancy  Jihyun Kim, MD, PhD, Byung Eui Kim, MD, PhD, Jeongok."— Presentation transcript:

1 Epidermal thymic stromal lymphopoietin predicts the development of atopic dermatitis during infancy 
Jihyun Kim, MD, PhD, Byung Eui Kim, MD, PhD, Jeongok Lee, PhD, Youngshin Han, PhD, Hyun-Young Jun, MS, Hyunmi Kim, MS, Jaehee Choi, MD, Donald Y.M. Leung, MD, PhD, Kangmo Ahn, MD, PhD  Journal of Allergy and Clinical Immunology  Volume 137, Issue 4, Pages e4 (April 2016) DOI: /j.jaci Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Flowchart of study population during the study period. The number of infants with AD indicates the cumulative number of patients who have developed AD at the time of evaluation. mo, Months. Journal of Allergy and Clinical Immunology  , e4DOI: ( /j.jaci ) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 Multivariable analysis for factors influencing AD development by age 24 months. When TSLP expression was dichotomized into low or high levels according to its median value and added to family history, the predictive value for AD development was further increased in subjects with family history and high TSLP expression than in those with family history alone. Male gender was independently linked with AD development. Multivariable analysis was done after adjustment for factors with P < .1 in univariable analysis. Journal of Allergy and Clinical Immunology  , e4DOI: ( /j.jaci ) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4 Fig E1 Comparison of the incidence of AD by age 24 months between the risk group and the control group. Statistical analysis was done using the Fisher exact test. *P < .05. Journal of Allergy and Clinical Immunology  , e4DOI: ( /j.jaci ) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5 Fig E2 Univariable analysis for epidermal proteins influencing AD development by age 24 months. OR, Odds ratio. Journal of Allergy and Clinical Immunology  , e4DOI: ( /j.jaci ) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

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