1. Origin and fate of phagocytes: a brief overview of the differentiation pathways of phagocytes and their fate.
Origin and fate of phagocytes: a brief overview of the differentiation pathways of phagocytes and their fate. Details are given in the text. Abbreviations: CFU-GEMM/GM/G/M: colony-forming unit granulocyte-erythrocyte-monocyte-megakaryocyte/granulocyte-monocyte/granulocyte/monocyte; AMP/MP alveolar macrophage/macrophage; Pox+/− gr, peroxidase-positive/negative granules; hl, half-life; BMR, bone marrow reserve; cGp/mGp, circulating/marginated granulocyte pool;, decrease; solid arrowheads, factors involved in cell maturation (for example, CSF and cytokines); open arrowheads, influence of the microenvironment in cell maturation (cell receptors and matrix proteins); dashed curved lines, self-renewal potential of phagocyte precursors.
Marie-Thérése Labro Clin. Microbiol. Rev. 2000; doi: /CMR