1. DementiaBank Progress and Future Plans
Michelle S. Bourgeois, PhD, CCC-SLP
University of South Florida

2. Project Description: Pitt Corpus https://dementia.talkbank.org/
The transcripts and audio files were gathered as part of a larger protocol administered by the Alzheimer and Related Dementias Study at the University of Pittsburgh School of Medicine.
The original acquisition of the DementiaBank data was supported by NIH grants AG and AG to the University of Pittsburgh, and NIH- NIDCD grant R01-DC for to Carnegie Mellon University.
Participants included elderly controls, people with probable and possible Alzheimer’s Disease, and people with other dementia diagnoses.
Data were gathered longitudinally, on a yearly basis.
Demographic data and test results from the rest of the protocol that was administered to all participants are included on the Data Spreadsheet for the Pitt Corpus available from the DementiaBank homepage.

3. 104 controls, 208 dementia, 85 unknown diagnosis
Participants:
104 controls, 208 dementia, 85 unknown diagnosis
Type of Study:
Longitudinal neuropsychological assessments
Location:
USA
Media type:
audio
Becker, J. T., Boller, F., Lopez, O. L., Saxton, J., & McGonigle, K. L. (1994). The natural history of Alzheimer's disease: description of study cohort and accuracy of diagnosis. Archives of Neurology, 51(6),

4. Tasks in the Alzheimer and Related Dementias Study protocol
Cookie Theft Picture Description
Repeat sentences after investigator  He is fishing with George.  Why don’t you give them some candy? 
How many…  days in a year?  inches in a foot?  eggs in a dozen?  senators to a state?  ounces in a pound? 
Word fluency  Name any thing you can find in a supermarket. (Timed)  Name all the items I (investigator) am wearing.  Things that begin with the letter “F”
Yes/No Questions (from Western Aphasia Battery)  Is your name Smith (Brown, Matthews)?  Do you live in Toronto (Pittsburgh, Windsor)?  Are you a woman (man)?  Are the lights on?  Is the door closed?  Do you eat a banana before you peel it? 
Name the item that…  you use to drink coffee/tea.  you use to fix your hair.  you use to tell the time.
What do you do with…  a razor?  soap?  a pencil? 
Read given sentences
Name the word that is being described  A prickly plant in the desert  An item used to hit a tennis ball  etc.

5. How are the following words alike
How are the following words alike?  Apple/banana (& Are these words names of fruits or animals?)  Coat/suit (& Are these words names of clothing or fruit?) 
Tell me a short, simple sentence using the given word(s)  Pencil  Child/hospital 
Name the word that does not belong  Dog, cat, car  Fish, car, train  Boy, door, man
Recall a story – Immediate and Delayed and Probe Questions  Sometimes the story is about a July 4th event with Uncle Bill and John fishing;  sometimes it’s about Thanksgiving with George, Melanie, and a trip to the city.
Does this sentence make sense? (If not, tell me why or correct the sentence.)  He drank some coffee.  Where's in the package?  I’m not as tall am I am.
Name the item (picture)  Maze  Toboggan 

6. Media and Transcript Database
Audio files were managed via Adobe Soundbooth software;
From ~100 volunteer undergraduate students from the Ohio State University and University of South Florida clipped audio segments from each file and transcribed them using the CLAN program and CHAT coding conventions.
Students’ transcriptions were checked for reliability within the lab (minimun 85% agreement); then linked to the audio file.
Transcripts were uploaded to Davida Fromm, TalkBank, who re-checked reliability and made corrections to the coding.
Transcripts and linked audio files were uploaded to DementiaBank.

7. Protocol Tasks transcribed
A. Cookie  These are responses to the Cookie Theft stimulus photo for the Control group and the Dementia group.
B. Fluency  These are responses to the Word Fluency task for the Dementia group only. These audio files have been transcribed by undergraduate student volunteers. The CHAT transcripts are in the process of being reviewed by an experienced transcriber (July 2016).
C. Recall  These are responses to the Story Recall task for the Dementia group only. These audio files have been transcribed by undergraduate student volunteers. The CHAT transcripts have not been reviewed by an experienced transcriber and should be considered rough first drafts.
D. Sentence  These are responses to the Sentence Construction task for the Dementia group only.

8. Dementia
Cookie Theft
Word Fluency
Sentence Recall
Sentence
Construction
Control
Cookie
Theft
Visit - 0
143
105
117
109 54
Visit - 1 56 41 48 40
Visit - 2 23 17 19 37
Visit - 3 9 8 21
Visit - 4 1 -- 4
Total
232
171
192
174
170

9. All of the current samples on DementiaBank.
Corpus
Description
Contributor
English Holland
Two individuals with Alzheimer's disease -- language tasks from a Telerounds presentation.
Audrey Holland
English Kempler
Six individuals with Alzheimer's disease -- conversation and Cookie Theft picture descriptions.
Dan Kempler
English Lanzi
Six individuals with mild neurocognitive disorder -- semi-structured interviews 1.5 years after group external memory aid treatment.
Alyssa Lanzi
English Pitt
Dementia and control data for four language tasks from a large longitudinal study.
Francois Boller and James Becker
English PPA DePaul
Primary Progressive Aphasia longitudinal data -- 1 participant
Roxanne DePaul
English PPA Hopkins
Primary Progressive Aphasia data
Argye Hillis
German PPA
Fedor Jalvingh
Mandarin_Lu
Dementia data participants.
Ching-ching Lu
Spanish PerLA
Dementia data individuals with Alzheimer's disease.
José Luis Mantero and Beatriz Gallardo-Pauls
Taiwanese_Lu
Dementia data participants.

10. Use of the DementiaBank data
161 DementiaBank Members from 30 countries
Publications and Presentations
84 total to date
Publications and Conference Proceedings: 74
Dissertation: 1
Master’s theses: 2
Undergraduate theses: 3
Posters: 4

11. Conference posters using DementiaBank data
Year - Conference
Authors
Title
Society for Personality and Social Psychology
Williams & Ireland
Linguistic cues to dementia in spontaneous speech: A dictionary-based analysis
CAC
Sung, Lee, DeDe, Oh, Shin, & Lee
Semantic-phonemic discrepancy and its changes over time in Alzheimer's disease: Evidence from clustering and switching analyses
Academy of Aphasia
Van der Woude, Faroqi-Shah, Ficek, Webster, & Tsapkini
Connected language in Primary Progressive Aphasia: Testing the utility of linguistic measures in differentially diagnosing PPA and its variants
AAIC
Field, Masrani, Murray & Carenini
Automatic detection of Alzheimer's from speech using spatial neglect markers
ASHA
DePaul, Busch, & Alfredson
Semantic Feature Analysis treatment using Spaced Retrieval in a case of semantic PPA
Lanzi, Lyndsay, & Bourgeois
Verbal fluency in dementia: Changes over time

12. Future Directions Limitation of current data set
Outdated Diagnostic parameters
Only Ad-probable, AD-possible, MCI.
Collection of new data
Define new dementia patient populations
Primary Progressive Aphasia (PPA; 3 subtypes), Frontotemporal (FTD), Lewy Body dementia, Parkinson’s dementia, Huntington’s dementia, LATE (TDP-43 protein)
Development of new Protocol
Consensus conference to develop common protocol
Develop Training/reliability procedures
Download new data for analysis