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Prevention and Management of Venous Thromboembolic Events in Patients With Multiple Myeloma.

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Presentation on theme: "Prevention and Management of Venous Thromboembolic Events in Patients With Multiple Myeloma."— Presentation transcript:

1 Prevention and Management of Venous Thromboembolic Events in Patients With Multiple Myeloma

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10 Anticoagulation Regimen Use unfractionated heparin or LMWH at a prophylactic dose for as long as the patient is on therapy

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15 Patient With Renal Failure Use full-dose warfarin

16 Patient With a History of VTE If > 1 VTE evaluate for a possible thrombophilia; in more difficult cases seek a multidisciplinary consult

17 Bortezomib-based (IMiD-less) Regimens No need for prophylaxis unless there are additional risk factors

18 Relapse Setting Prophylaxis for Patients on Pomalidomide-based Therapy

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20 IMiD-only Regimens No prophylaxis or use low-dose aspirin

21 Patient on IMiD-based Regimen Who Develops a DVT or PE Continue or stop therapy while increasing level of anticoagulation?

22 Patient Who Develops a Catheter-related Thrombosis Interrupt therapy while the patient is appropriately managed, then resume therapy

23 Patients on IMiDs The risk for thrombosis is greatest during the first few months of therapy

24 Patients on IMiDs Need for routine screening in the absence of symptoms

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