1. Chronotherapy of asthma with inhaled steroids: The effect of dosage timing on drug efficacy 
Diane J. Pincus, MD, Stanley J. Szefler, MD, Lynn M. Ackerson, PhD, Richard J. Martin, MD 
Journal of Allergy and Clinical Immunology 
Volume 95, Issue 6, Pages (June 1995)
DOI: /S (95)
Copyright © 1995 Mosby, Inc. Terms and Conditions

2. FIG. 1
FEV 1 at baseline and after 4 weeks of treatment for QD and QID groups. Both groups demonstrate significant improvement after inhaled steroid therapy. Between groups there are no significant differences at baseline or after 4 weeks of treatment.
Journal of Allergy and Clinical Immunology  , DOI: ( /S (95) )
Copyright © 1995 Mosby, Inc. Terms and Conditions

3. FIG. 2
Morning (AM) PEFR is shown at baseline and after 4 weeks of treatment for QD and QID groups. Both groups demonstrate significant improvement after inhaled steroid therapy. Between groups there are no significant differences at baseline or after 4 weeks of treatment.
Journal of Allergy and Clinical Immunology  , DOI: ( /S (95) )
Copyright © 1995 Mosby, Inc. Terms and Conditions

4. FIG. 3
Evening (PM) PEFR is shown at baseline and after 4 weeks of treatment for QD and QID groups. Both groups demonstrate significant improvement after inhaled steroid therapy. Between groups there are no significant differences at baseline or after 4 weeks of treatment.
Journal of Allergy and Clinical Immunology  , DOI: ( /S (95) )
Copyright © 1995 Mosby, Inc. Terms and Conditions

5. FIG. 4
The improvement in morning (AM) PEFR and evening (PM) PEFR is compared for the QD and QID groups. The improvement in morning PEFR was similar for each treatment group. There was a trend toward more improvement in evening PEFR for the QD group compared with the QID group.
Journal of Allergy and Clinical Immunology  , DOI: ( /S (95) )
Copyright © 1995 Mosby, Inc. Terms and Conditions