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Evacuation of microscopic air bubbles from Dacron reduces complement activation and platelet aggregation  Peter G. Kalman, MD, FRCS(C), Denise A. McCullough,

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Presentation on theme: "Evacuation of microscopic air bubbles from Dacron reduces complement activation and platelet aggregation  Peter G. Kalman, MD, FRCS(C), Denise A. McCullough,"— Presentation transcript:

1 Evacuation of microscopic air bubbles from Dacron reduces complement activation and platelet aggregation  Peter G. Kalman, MD, FRCS(C), Denise A. McCullough, Charles A. Ward, PhD  Journal of Vascular Surgery  Volume 11, Issue 4, Pages (April 1990) DOI: / (90)90308-W Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

2 Fig. 1 Platelet aggregation assay. The incubated plasma samples have been added to a platelet suspension. The vertical deflection in centimeters on the recording is related to the light transmitted through the platelet suspension; the greater the aggregation, the greater the deflection. The height of deflection after 30 seconds is read in centimeters above the baseline and is noted for each sample. Journal of Vascular Surgery  , DOI: ( / (90)90308-W) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

3 Fig. 2 C3a des-Arg and C5a des-Arg concentration comparing air bubble stimulated plasma with plasma control. There was no difference observed for C4a des-Arg. Journal of Vascular Surgery  , DOI: ( / (90)90308-W) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

4 Fig. 3 Platelet aggregation comparing plasma stimulated with air bubbles with plasma control. Journal of Vascular Surgery  , DOI: ( / (90)90308-W) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

5 Fig. 4 C3a des-Arg concentration comparing denucleated Dacron with control Dacron pieces (2, 4, 6 cm2) (different at all sizes, p = 0.042, p = 0.019, 0.027, respectively). Journal of Vascular Surgery  , DOI: ( / (90)90308-W) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

6 Fig. 5 C5a des-Arg concentration comparing denucleated Dacron with control Dacron pieces (2, 4, 6 cm2) (different at all sizes, p = 0.012, p = 0.023, p = 0.003, respectively). Journal of Vascular Surgery  , DOI: ( / (90)90308-W) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

7 Fig. 6 Platelet aggregation comparing denucleated Dacron with control Dacron pieces (2, 6 cm2) (different at all sizes, p = 0.001, p = , respectively). Journal of Vascular Surgery  , DOI: ( / (90)90308-W) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

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