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Antibacterial activity, antibiotic retention, and infection resistance of a rifampin- impregnated gelatin-sealed Dacron graft  Kevin Lachapelle, MD, Alan.

Published byBjörn Eklund Modified over 5 years ago

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Presentation on theme: "Antibacterial activity, antibiotic retention, and infection resistance of a rifampin- impregnated gelatin-sealed Dacron graft  Kevin Lachapelle, MD, Alan."— Presentation transcript:

1 Antibacterial activity, antibiotic retention, and infection resistance of a rifampin- impregnated gelatin-sealed Dacron graft  Kevin Lachapelle, MD, Alan M. Graham, MD, James F. Symes, MD  Journal of Vascular Surgery  Volume 19, Issue 4, Pages (April 1994) DOI: /S (94) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

2 Fig. 1 Mean concentrations of rifampin in serum, perigraft fluid, and homogenized aorta in four pigs after administration of 15 mg/kg intravenous rifampin. Journal of Vascular Surgery  , DOI: ( /S (94) ) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

3 Fig. 2 Mean concentration of rifampin per gram of graft for 4 days after graft implantation in pigs. Journal of Vascular Surgery  , DOI: ( /S (94) ) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

4 Fig. 3 Mean concentration of rifampin in serum and perigraft fluid for 4 days after graft implantation in pigs. Journal of Vascular Surgery  , DOI: ( /S (94) ) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

5 Fig. 4 Infection rate in control pigs (group I), pigs given intravenous (IV) rifampin for 3 days after surgery (group II), and pigs with grafts impregnated with rifampin (group III). Journal of Vascular Surgery  , DOI: ( /S (94) ) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

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