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Percentage of patients with RA achieving DAS28(CRP)<2

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Presentation on theme: "Percentage of patients with RA achieving DAS28(CRP)<2"— Presentation transcript:

1 Percentage of patients with RA achieving DAS28(CRP)<2
Percentage of patients with RA achieving DAS28(CRP)<2.6 (left panel) or SDAI≤3.3 (right panel) at week 24 or 26 who subsequently met criteria for CDC, clinical remission, non-progression of joint damage or normal physical function at week 52 in (A) DE019, (B) PREMIER and (C) the Rescue ADA arm of OPTIMA. The last observation carried forward imputation method was used for patients with missing DAS28(CRP) and HAQ-DI data. Percentage of patients with RA achieving DAS28(CRP)<2.6 (left panel) or SDAI≤3.3 (right panel) at week 24 or 26 who subsequently met criteria for CDC, clinical remission, non-progression of joint damage or normal physical function at week 52 in (A) DE019, (B) PREMIER and (C) the Rescue ADA arm of OPTIMA. The last observation carried forward imputation method was used for patients with missing DAS28(CRP) and HAQ-DI data. Linear extrapolation was conducted for patients with missing mTSS data. The non-responder imputation method was used for patients without any postbaseline DAS28(CRP), HAQ-DI or mTSS data. ADA, adalimumab; CDC, comprehensive disease control; DAS28(CRP), 28-joint Disease Activity Score based on C-reactive protein; HAQ-DI, Health Assessment Questionnaire Disability Index; IR, inadequate response; ΔmTSS, change in modified total Sharp score; MTX, methotrexate; PBO, placebo; RA, rheumatoid arthritis; SDAI, Simplified Disease Activity Index. Edward C Keystone et al. RMD Open 2017;3:e000445 Copyright © BMJ Publishing Group & EULAR. All rights reserved.

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