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Mean ± SEM concentration of insulin in plasma and CSF and glucose in plasma 30 min after the intraperitoneal administration of DET or NPH insulin at different.

Published byClement Moore Modified over 4 years ago

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Presentation on theme: "Mean ± SEM concentration of insulin in plasma and CSF and glucose in plasma 30 min after the intraperitoneal administration of DET or NPH insulin at different."— Presentation transcript:

1 Mean ± SEM concentration of insulin in plasma and CSF and glucose in plasma 30 min after the intraperitoneal administration of DET or NPH insulin at different doses in rats. Mean ± SEM concentration of insulin in plasma and CSF and glucose in plasma 30 min after the intraperitoneal administration of DET or NPH insulin at different doses in rats. Intraperitoneal NPH insulin and DET produced similar levels as a function of dose in plasma (A and D). Likewise, there were dose-dependent increases of CSF insulin with both NPH insulin and DET, with apparent saturation of the CSF insulin levels occurring by the 3 units/kg dose (B and E). Plasma glucose decreased in a dose-dependent manner after intraperitoneal NPH insulin or DET (C and F). Significant differences are described in the text. Denovan P. Begg et al. Diabetes 2015;64: ©2015 by American Diabetes Association

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